ChemicalBook >> CAS DataBase List >>USNIC ACID

USNIC ACID

CAS No.
125-46-2
Chemical Name:
USNIC ACID
Synonyms
usno;Usnic;USNEIN;USNIACIN;UNSICACID;SNIC ACID;USNIC ACID;Usnea acid;usninsaeure;2-USNICACID
CBNumber:
CB6237422
Molecular Formula:
C18H16O7
Molecular Weight:
344.32
MDL Number:
MFCD00065294
MOL File:
125-46-2.mol
MSDS File:
SDS
Last updated:2024-04-22 15:59:48

USNIC ACID Properties

Melting point 200°C
alpha D16 +509.4° (c = 0.697 in chloroform)
Boiling point 399.43°C (rough estimate)
Density 1.2869 (rough estimate)
refractive index 495 ° (C=0.7, CHCl3)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMF:2.5(Max Conc. mg/mL);7.26(Max Conc. mM)
form A crystalline solid
pka 4.00±0.40(Predicted)
Merck 9893
LogP 2.880
CAS DataBase Reference 125-46-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 0W584PFJ77
EPA Substance Registry System Usnic acid (125-46-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H335
Precautionary statements  P261
Hazard Codes  T,N
Risk Statements  25-50/53
Safety Statements  22-24/25-61-60-45
RTECS  HP5270000
Toxicity LD50 i.v. in mice: 25 mg/kg (Gottlieb, Shaw)
NFPA 704
0
2 0

USNIC ACID price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22585 Usnic Acid ≥98% 125-46-2 1g $25 2024-03-01 Buy
Cayman Chemical 22585 Usnic Acid ≥98% 125-46-2 5g $61 2024-03-01 Buy
Cayman Chemical 22585 Usnic Acid ≥98% 125-46-2 10g $107 2024-03-01 Buy
Cayman Chemical 22585 Usnic Acid ≥98% 125-46-2 25g $202 2024-03-01 Buy
TRC U850153 UsnicAcid 125-46-2 10g $100 2021-12-16 Buy
Product number Packaging Price Buy
22585 1g $25 Buy
22585 5g $61 Buy
22585 10g $107 Buy
22585 25g $202 Buy
U850153 10g $100 Buy

USNIC ACID Chemical Properties,Uses,Production

Chemical Properties

Crystalline, yellow solid. Insoluble in water; slightly soluble in alcohol and ether.

Uses

antibacterial

Uses

Usnic acid is an enzyme inhibiting antitumor agent.

Uses

Usnic acid is a major metabolite from a number of lichen and fungal species and is perhaps one of the longest known microbial metabolites, first isolated in 1844. Usnic acid exhibits a broad range of biological activity, indeed it is easier to list the bioassays in which it does not exhibit activity. More often than not, potency is low and of limited value. Usnic acid is an important metabolite for dereplication in discovery research programs.

Definition

ChEBI: A member of the class of dibenzofurans that is dibenzo[b,d]furan-1(9bH)-one substituted by acetyl groups at positions 2 and 6, hydroxy groups at positions 3 and 7 and methyl groups at positions 8 and 9b.

Contact allergens

Usnic acid is a component of lichens, also used as a topical antibiotic. Allergic contact dermatitis from lichens occurs mainly occupationally in forestry and horticultural workers, and in lichen pickers.

Purification Methods

This very weak acid is the natural form which is recrystallised from Me2CO, MeOH or *C6H6. At 25o it is soluble in H2O (<0.01%), Me2CO (0.77%), EtOAc (0.88%), MeOCH2CH2OH (0.22%) and furfural (7.32%). [Curd & Robertson J Chem Soc 894 1937, Barton & Brunn J Chem Soc 603 1953, resolution: Dean et al. J Chem Soc 1250 1953, synthesis: Barton et al. J Chem Soc 538 1956, Beilstein 18/5 V 586.]

USNIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 296)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Hangzhou ICH Biofarm Co., Ltd
+undefined8613073685410 sales@ichemie.com China 985 58
Ouhuang Engineering Materials (Hubei) Co., Ltd
+8617702722807 admin@hbouhuang.com China 1696 58
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691 yklbiotech@163.com CHINA 296 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58

View Lastest Price from USNIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
USNIC ACID pictures 2024-04-23 USNIC ACID
125-46-2
US $0.00-0.00 / kg 1kg 1-98% 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
Usnea acid  pictures 2024-04-23 Usnea acid
125-46-2
US $0.00-0.00 / kg 1kg 98% 10000 Changsha Staherb Natural Ingredients Co., Ltd.
(±)-Usnic acid pictures 2024-04-22 (±)-Usnic acid
125-46-2
US $15.00 / kg 1kg 99.912% 10ton Ouhuang Engineering Materials (Hubei) Co., Ltd
  • USNIC ACID pictures
  • USNIC ACID
    125-46-2
  • US $0.00-0.00 / kg
  • 1-98%
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • Usnea acid  pictures
  • Usnea acid
    125-46-2
  • US $0.00-0.00 / kg
  • 98%
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • (±)-Usnic acid pictures
  • (±)-Usnic acid
    125-46-2
  • US $15.00 / kg
  • 99.912%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
(+-)-uanicacid 2,6-diacetyl-1, 2,6-diacetyl-1,2,3,9b-tetrahydro-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2h,9bh)-dibenzofurandione Usnic acid, usinic acid 10 GM and 25 GM Carbonusninic acid 2,6-diacetyl-7,9-dihydroxy-8,9b-diMethyldibenzo[b,d]furan-1,3(2H,9bH)-dione Usninic acid, Carbonusninic acid, Usno Usnic acid/Usnic acid sodium D-2,6-Diacetyl-7 3(2H,9bH)-Dibenzofurandione,2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1 9bh)-dibenzofurandione,2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-3(2h usninsaeure usno Usnic 1,3(2H,9bH)-Dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl- USNIC ACID, (+)-(RG) Usnein,Usniacin,Usninicacid UNSICACID 2-hydroxy-6-methylanisic acid USNINIC ACID USNEIN USNIACIN USNIC ACID Antibiotic lichen acid 2,6-DIACETYL-7,9-DIHYDROXY-8,9B-DIMETHYL-9BH-DIBENZOFURAN-1,3-DIONE Usnea acid Pine nut acid 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione 2-USNICACID USNIC ACID USP/EP/BP SNIC ACID Usnic Acid, ≥ 98.0% 125-46-2 C18H16O7 CH3OC6H2OHCH3COOH Inhibitors chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Miscellaneous Natural Products 231-456-0