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ISOCORYDINE HYDROCHLORIDE

CAS No.
475-67-2
Chemical Name:
ISOCORYDINE HYDROCHLORIDE
Synonyms
luteanin;LUTEANINE;artabotrin;Aids138466;Uzokoridin;Isocorydine;Aids-138466;d-isocorydine;l-(+)-isocorydine;S-ISOCORYDINE (+)
CBNumber:
CB6238999
Molecular Formula:
C20H23NO4
Molecular Weight:
341.4
MDL Number:
MFCD00075905
MOL File:
475-67-2.mol
Last updated:2023-09-04 16:42:00

ISOCORYDINE HYDROCHLORIDE Properties

Melting point 216-220 °C(lit.)
alpha D20 +195° (chloroform)
Boiling point 477.03°C (rough estimate)
Density 1.2064 (rough estimate)
refractive index 1.5614 (estimate)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Cryst.
pka 9.41±0.20(Predicted)
FDA UNII 3B5E87JEOX

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  CE1057950
Toxicity LD50 intraperitoneal in mouse: 104mg/kg

ISOCORYDINE HYDROCHLORIDE price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30101 Isocorydine 475-67-2 10mg $56 2024-03-01 Buy
Cayman Chemical 30101 Isocorydine 475-67-2 25mg $116 2024-03-01 Buy
Cayman Chemical 30101 Isocorydine 475-67-2 5mg $37 2024-03-01 Buy
Cayman Chemical 30101 Isocorydine 475-67-2 50mg $178 2024-03-01 Buy
Usbiological 361810 Isocorydine 475-67-2 20mg $546 2021-12-16 Buy
Product number Packaging Price Buy
30101 10mg $56 Buy
30101 25mg $116 Buy
30101 5mg $37 Buy
30101 50mg $178 Buy
361810 20mg $546 Buy

ISOCORYDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Isocorydine is an aporphine alkaloid that has been found in A. squamosa that has vasodilatory and anticancer activities. It reduces the action potential duration and increases the effective refractory period in isolated canine Purkinje fibers when used at a concentration of 30 μM. Isocorydine induces relaxation of norepinephrine-precontracted isolated rabbit aortic strips with an EC50 value of 12.6 μM. It is cytotoxic to A549 lung cancer cells (IC50 = 197.7 μM), as well as Huh7, HepG2, SNU-449, and SNU-387 hepatic cancer cells (IC50s = 161.3, 148, 262.2, and 254.1 μg/ml, respectively). Isocorydine, in combination with doxorubicin, reduces tumor growth in a Huh7 mouse xenograft model.

Uses

Isocorydine is an alkaloid inhibitor of eukaryotic kinases.

Uses

sedative, cholinergic

Uses

Isocorydine Hydrochloride is the hydrochloric acid of Isocorydine(I797000) which is an alkaloid inhibitor of eukaryotic kinases.

Definition

ChEBI: Isocorydine is an aporphine alkaloid.

target

Dopamine Receptor | P450 (e.g. CYP17)

References

See Isocorydine

ISOCORYDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 146)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253 jancyzheng@gcgreenpure.com China 952 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10326 58

View Lastest Price from ISOCORYDINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isocorydine pictures 2023-02-24 Isocorydine
475-67-2
US $0.00 / mg 20mg ≥98%(HPLC) 100 g Shanghai Standard Technology Co., Ltd.
ISOCORYDINE HYDROCHLORIDE pictures 2020-01-10 ISOCORYDINE HYDROCHLORIDE
475-67-2
US $9.80 / KG 1KG ≥98% 20 tons Career Henan Chemical Co
  • Isocorydine pictures
  • Isocorydine
    475-67-2
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.

ISOCORYDINE HYDROCHLORIDE Spectrum

LUTEANINE LUTEANINE HYDROCHLORIDE 1,2,10-trimethoxy-6a-alpha-aporphin-11-o 4h-dibenzo(de,g)quinolin-11-ol,5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methy artabotrin d-isocorydine l-(+)-isocorydine luteanin luteanine(aporphine) D-ISOCORYDINE HYDROCHLORIDE (+)-ISOCORYDINE HCL ISOCORYDINE HCL, (+)- (+)-ISOCORYDINE HYDROCHLORIDE ISOCORYDINE HYDROCHLORIDE (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE HYDROCHLORIDE (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol [6aS,(+)]-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol Isocorydine S-ISOCORYDINE (+) 1,2,10-Trimethoxy-6-methyl-5,6,6A,7-tetrahydro-4H-dibenzo[de,G]quinolin-11-ol Aids138466 Aids-138466 Aporphin-11-ol, 1,2,10-trimethoxy- (+)-isocorynoline (+)-Isocorynoline hydrochloride Uzokoridin 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6aS)- 475-67-2 Analytical Chromatography Product Catalog Analytical Standards Asymmetric Synthesis Chiral Building Blocks Others Drug Standards Chromatography Forensic and Veterinary Standards Heterocyclic Building Blocks Inhibitors Miscellaneous Natural Products Alkaloids