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SINOMENINE HYDROCHLORIDE

CAS No.
6080-33-7
Chemical Name:
SINOMENINE HYDROCHLORIDE
Synonyms
Sinomenin HCl;SINOMENINE HCL;Cucoline hydrochloride;Kukoline hydrochloride;Sinomenine Hydrocloride;SINOMENINE HYDROCHLORIDE;Tuduranine Hydrochloride;Sinomenine HCl Dihydrate;Sabianine A hydrochloride;Sinomenine Hydrochloride >
CBNumber:
CB6245173
Molecular Formula:
C19H24ClNO4
Molecular Weight:
365.85
MDL Number:
MFCD01714307
MOL File:
6080-33-7.mol
Last updated:2023-07-28 17:44:41

SINOMENINE HYDROCHLORIDE Properties

Melting point 231.0 to 235.0 °C
storage temp. Inert atmosphere,2-8°C
solubility H2O: soluble20mg/mL, clear
form powder
color white to beige
optical activity [α]/D -70 to -90°, c = 1 in H2O
Water Solubility Soluble to 100 mM in water
FDA UNII 2J34HRJ45S

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335-H351
Precautionary statements  P201-P280-P301+P312+P330-P302+P352+P312-P304+P340+P312-P308+P313
Safety Statements  24/25
WGK Germany  3
RTECS  QD2163000
HS Code  29334900
NFPA 704
0
3 0

SINOMENINE HYDROCHLORIDE price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1002 Sinomenine hydrochloride ≥98% (HPLC) 6080-33-7 50mg $118 2024-03-01 Buy
TCI Chemical S0926 Sinomenine Hydrochloride >98.0%(HPLC)(T) 6080-33-7 1g $117 2023-01-07 Buy
TCI Chemical S0926 Sinomenine Hydrochloride >98.0%(HPLC)(T) 6080-33-7 5g $402 2022-04-27 Buy
Cayman Chemical 16143 Sinomenine (hydrochloride) ≥98% 6080-33-7 50mg $32 2024-03-01 Buy
Cayman Chemical 16143 Sinomenine (hydrochloride) ≥98% 6080-33-7 100mg $44 2024-03-01 Buy
Product number Packaging Price Buy
SML1002 50mg $118 Buy
S0926 1g $117 Buy
S0926 5g $402 Buy
16143 50mg $32 Buy
16143 100mg $44 Buy

SINOMENINE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Sinomenine is a natural plant alkaloid commonly used to alleviate inflammation associated with rheumatoid arthritis. It activates histamine release, reduces joint stiffness and pain, and alters cytokine generation without producing gastrointestinal adverse events. Sinomenine also impairs signaling through NF-κB, resulting in immunosuppression as well as reduced inflammation and pain. It enhances the bioavailability of some compounds, at least in part through an inhibition of drug export by transporters like P-glycoprotein.

Chemical Properties

White Solid

Uses

Sinomenine is an optical isomer of Methoxythebainone. Sinomenine was extracted from root of Sinomenium acutum. Sinomenine has anti-inflammatory and analgesic effect.

Purification Methods

Crystallise the salt from water (1g/1.5mL) or EtOH. The free base [115-53-7] M 329.4, has m 161o (from EtOH) (and again at 182o) after crystallisation from *C6H6, and [] D 20 -78.9o (c 1, EtOH). The picrate has m 159-162o(dec) (from H2O). [Beilstein 21 II 470, 21 III/IV 6670.]

SINOMENINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 205)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691 yklbiotech@163.com CHINA 296 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58

View Lastest Price from SINOMENINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SINOMENINE HYDROCHLORIDE pictures 2024-04-09 SINOMENINE HYDROCHLORIDE
6080-33-7
US $0.00 / KG 1KG ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
SINOMENINE HYDROCHLORIDE pictures 2023-07-29 SINOMENINE HYDROCHLORIDE
6080-33-7
US $0.00-0.00 / kg 1kg 0.99 50000kg Hebei Yibangte Import and Export Co. , Ltd.
Sinomenine Hydrochloride pictures 2023-02-24 Sinomenine Hydrochloride
6080-33-7
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.

SINOMENINE HYDROCHLORIDE Spectrum

(9a,13a,14a)-4-Hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochloride SINOMENINE HYDROCHLORIDE SINOMENINE HCL (9α,13α,14α)- 7,8-Didehydro-4- hydroxy-3,7-diMet 7,8-Didehydro-4-hydroxy-3,7-diMethoxy-17-Methyl- 9α,13α,14α-Morphinan-6-one Hydrochloride Tuduranine Hydrochloride hydroxy-dimethoxy-methyl-BLAH-azatetracyclo[BLAH]hexadeca-BLAH,BLAH,BLAH,BLAH-tetraenone Sinomenine Hydrocloride Cucoline hydrochloride Sinomenine hydrochloride (Cucoline hydrochloride) Sinomenine Hydrochloride > Kukoline hydrochloride Sabianine A hydrochloride TIANFU-CHEM CAS:6080-33-7 SINOMENINE HYDROCHLORIDE 9α,13α,14α-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, hydrochloride Sinomenine hydrochloride (Cucoline) Sinomenine HCl Dihydrate Sinomenine hydrochloride (6CI, 7CI) Sinomenin HCl 98% Sinomenine Hydrochloride Powder Sinomenine Hydrochloride, ≥ 98.0% 6080-33-7 C19H23NO4HCl Alkaloids Inhibitors pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract chemical reagent Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals APIs