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2'-O-MOE-5MeU-3'-phosphoramidite

2'-O-MOE-5MeU-3'-phosphoramidite structure

CAS No.: 163878-63-5

Chemical Name:: 2'-O-MOE-5MeU-3'-phosphoramidite

Synonyms: 5-Me-DMT-2'-O-Me-Ur;5'-O-DMT-2'-O-MOE-T-CE;5-Me-DMT-2'-O-MOE-U-CE;2'-MOE Thymidine Amidite;2'-MOE-U CE Phosphoramidite;5-Methyl-2 '- Methoxyuridine;2'-O-MOE-T-CE Phosphoramidite;2'-O-MOE-5-Me-U Phosphoramidite;2’-O-MOE-5MeU-3’-phosphoramidit;2'-O-MOE-5MeU-3'-phosphoramidite

CBNumber:: CB62459682

Molecular Formula:: C43H55N4O10P

Molecular Weight:: 818.89

MDL Number:: MFCD11505865

MOL File:: 163878-63-5.mol

MSDS File:: SDS

Last updated:2023-12-13 11:34:41

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2'-O-MOE-5MeU-3'-phosphoramidite Properties

pka	9.55±0.10(Predicted)
InChIKey	YFRRKZDUDXHJNC-UHDLEJOUNA-N
SMILES	O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N \|&1:25,27,37,43,r\|

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P330-P501

2'-O-MOE-5MeU-3'-phosphoramidite Chemical Properties,Uses,Production

Chemical Properties

white to off-white powder

Uses

5''-O-DMT-2''-O-methyl-5-methyluridine is a uridine-derived oligonucleoside (U829910) used in the synthetic preparation of nucleic acids.

General Description

2'-O-MOE-5MeU-3'-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

General Description

Like the very similar 2’-OMe backbone, the 2’-O-methoxyethyl-RNA (2’-MOE) backbone provides enhanced duplex stability, significant nuclease resistance and relatively low toxicity. As a result, 2’-MOE has been an attractive backbone for many therapeutic candidates, several of which have been approved by the FDA. These drugs have included 1) 2’-MOE/DNA chimeras to facilitate RNase H cleavage of target RNA sequences as well as 2) steric blocking oligonucleotides to alter the splicing of mRNA. The standard 2’-MOE nucleotides are A, 5-Me-C, G and 5-Me-U.

2'-O-MOE-5MeU-3'-phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

2'-O-MOE-5MeU-3'-phosphoramidite Suppliers

Global( 91)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hefei Huana Biomedical Technology Co.,Ltd.	+86-15900695956	shiqin.he@huanaok.com.cn	China	96	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15932	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10026	58
Zhejiang Hengkang Pharmaceutical Co., Ltd.	+86-576-83372028 +86-18868723926	bd1@hengkangpharm.cn	China	119	58
Wuhu Nuowei chemistry Co., Ltd.	+86-0553-2911116-802 +undefined17756524438	sales1@nuowei-chem.com	China	1642	58
Henan Aochuang Chemical Co.,Ltd.	+86-0371-63689365 +8618638391208	sales@aochuangchem.com	China	9425	58
Chemtour Biotech Co., Ltd	+8617327281506	market@chemtour.com	China	1472	58
SHANGHAI NOVRIBO BIOTECH	17821030819	June.Liu@Desano.com	China	73	58

Supplier	Advantage
Hefei Huana Biomedical Technology Co.,Ltd.	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Shenzhen Nexconn Pharmatechs Ltd	58
BOC Sciences	58
NewCan Biotech Limited	58
Zhejiang Hengkang Pharmaceutical Co., Ltd.	58
Wuhu Nuowei chemistry Co., Ltd.	58
Henan Aochuang Chemical Co.,Ltd.	58
Chemtour Biotech Co., Ltd	58
SHANGHAI NOVRIBO BIOTECH	58

View Lastest Price from 2'-O-MOE-5MeU-3'-phosphoramidite manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-04-04	DMT-2′O-MOE-rMeU Phosphoramidite 163878-63-5	US $0.00-0.00 / kg	1kg	98%	500kg per month	Zhejiang Hengkang Pharmaceutical Co., Ltd.
2023-03-21	2'-MOE-U CE Phosphoramidite 163878-63-5	US $100.00 / kg	0.009999999776482582kg	99%	5tons	SHANGHAI NOVRIBO BIOTECH
2023-03-14	5'-O-DMT-2'-O-MOE-T-CE 163878-63-5	US $0.00 / mg	100mg	≥98%	20tons	Hefei Huana Biomedical Technology Co.,Ltd.

DMT-2′O-MOE-rMeU Phosphoramidite
163878-63-5
US $0.00-0.00 / kg
98%
Zhejiang Hengkang Pharmaceutical Co., Ltd.

2'-MOE-U CE Phosphoramidite
163878-63-5
US $100.00 / kg
99%
SHANGHAI NOVRIBO BIOTECH

5'-O-DMT-2'-O-MOE-T-CE
163878-63-5
US $0.00 / mg
≥98%
Hefei Huana Biomedical Technology Co.,Ltd.

163878-63-5(2'-O-MOE-5MeU-3'-phosphoramidite)Related Search:

N2-iso-Butyroyl-5'-(4,4'-dimethoxytrityl)-2'-O-propargylguanosine 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine 2'-O-TBDMS-5'-O-DMT-N4-Ac cytidin 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyl-D-adenosine

5'-O-DMT-2'-O-methyl-5-methyluridine 5-Me-DMT-2'-O-Me-Ur 5-Methyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-uridine 2'-O-MOE-5MeU-3'-phosphoramidite 5'-O-DMTR-2'-O-(2-METHOXYETHYL)-5-METHYLURIDINE-3'-CED-PHOSPHORAMIDITE 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyluridine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] (2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-4-(2-METHOXYETHOXY)-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE 2-O-MOE-5-Methyl-Uridine Phosphoramidite 2'-O-MOE-T-CE Phosphoramidite 5-methyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-uridine-3'-cyanoethyl Phosphoramidite DMT-2'-O-MOE-T-CE-Phosphoramidite Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] 5’-O-DMTr-2’-O-(2-methoxyethyl)-5-methyluridine-3’-CED-phosphoramidite, 2’-O-MOE -5MeU-3’-phosphoramidite 5'-O-DMT-5-Methy-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite 2'-O-MOE-5-Me-U Phosphoramidite 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-uridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite DMT-2′O-MOE-rMeU Phosphoramidite 5'-O-DMT-2’-MOE-5-methyluridine-CE-Phosphoramidite 5-Me-DMT-2'-O-MOE-U-CE-Phosphoramidite 2’-O-MOE-5MeU-3’-phosphoramidite,5’-O-DMTr-2’-O-(2-methoxyethyl)-5-methyl uridine-3’-CED-phosphoramidite MOE-5MeU-PAM 2’-O-MOE-5MeU-3’-phosphoramidit 2'-O-MOE-5-Me-U -CE Phosphoramidite 5'-O-DMT-2'-O-MOE-T-CE 2'-MOE-U CE Phosphoramidite 5'-O-DMT-2'-O-MOE- 5-Me-Uridine -3’-Cyanoethyl Phosphoramidite 2'-MOE Thymidine Amidite 5-Me-DMT-2'-O-MOE-U-CE DMT-2''O-MOE-rMeU Amidite，septum 5-Methyl-2 '- Methoxyuridine DMTr-2'-O-MOE-rT-3'-CE-Phosphoramidite 2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE 5’-O-(4, 4’-Dimethoxytrityl)-5-methyl-2’-O-(2-methoxyethyl)uridine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-ODMT-2'-OMOE-5-methyluridine-3'-OCEPA 2’-O-MOE-5MeU-3’-phospho ramidite DMT-2'-O-MOE-T-CE-Phosphoramidite 163878-63-5 C43H55N4O10P Amidite