(S)-Ketorolac
- CAS No.
- 66635-92-5
- Chemical Name:
- (S)-Ketorolac
- Synonyms
- Ketorolac S-IsoMer;(S)-Ketorolac ISO 9001：2015 REACH;Ketorolac impurity 2/Ketorolac S-Isomer;Phosphorousacid,tris(1,5-dimethylethyl)ester;1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1S)-
- CBNumber:
- CB62485724
- Molecular Formula:
- C15H13NO3
- Molecular Weight:
- 255.27
- MDL Number:
- MFCD00871493
- MOL File:
- 66635-92-5.mol
| Melting point | 160-167?C |
|---|---|
| Boiling point | 493.2±40.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform: Slightly; Ethanol: >1mg/ml; Methanol: Slightly |
| form | A crystalline solid |
| pka | 4.29±0.20(Predicted) |
| FDA UNII | 5H3TJ0A81K |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P405-P501 |
(S)-Ketorolac price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML3299 | S-Ketorolac ≥98% (HPLC) | 66635-92-5 | 5MG | $116 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML3299 | S-Ketorolac ≥98% (HPLC) | 66635-92-5 | 25MG | $469 | 2023-06-20 | Buy |
| Cayman Chemical | 11348 | (S)-Ketorolac ≥98% | 66635-92-5 | 1mg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 11348 | (S)-Ketorolac ≥98% | 66635-92-5 | 5mg | $414 | 2024-03-01 | Buy |
| TRC | K235605 | (S)-Ketorolac | 66635-92-5 | 2mg | $155 | 2021-12-16 | Buy |
(S)-Ketorolac Chemical Properties,Uses,Production
Description
(S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 μM for COX-1 and COX-2, respectively). (S)-Ketorolac is approximately twice as potent as the racemic mixture and 60 times more potent than (R)-ketorolac in a rat pain assay. (S)-Ketorolac is cleared from rat kidney and liver more quickly than (R)-ketorolac. Formulations containing ketorolac have been used to manage postoperative pain as well as an ophthalmic solution to treat ocular pain and inflammation.
Chemical Properties
Off-White Solid
Uses
The R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
Uses
(S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
Definition
ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known s mply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
(S)-Ketorolac Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9553 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29474 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3582 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
View Lastest Price from (S)-Ketorolac manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-17 | (S)-Ketorolac
66635-92-5
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2021-10-22 | (S)-Ketorolac
66635-92-5
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- (S)-Ketorolac
66635-92-5
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- (S)-Ketorolac
66635-92-5
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
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