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3-Chloroisonicotinic acid

CAS No.
88912-27-0
Chemical Name:
3-Chloroisonicotinic acid
Synonyms
3-CHLOROISONICOTINIC ACID;3- chlorineisonicotinic acid;3-Chloroisonicotinic Acid >3-Chloro-4-pyridine carboxlic acid;3-CHLORO-4-PYRIDINECARBOXYLIC ACID;3-CHLOROPYRIDINE-4-CARBOXYLIC ACID;3-Chloropyridin-4-ylcarboxylic acid;4-Pyridinecarboxylic acid, 3-chloro-;3-Chloropyridine-4-carboxylic acid 97%;3-Chloropyridine-4-carboxylic Acid, 97+%
CBNumber:
CB6249797
Molecular Formula:
C6H4ClNO2
Molecular Weight:
157.55
MDL Number:
MFCD03094685
MOL File:
88912-27-0.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:47
Product description Number Pack Size Price
3-Chloropyridine-4-carboxylic acid 97% 633410 1g $31.7
3-Chloropyridine-4-carboxylic acid 97% 633410 5g $38.4
3-Chloroisonicotinic Acid >98.0%(GC)(T) C2983 5g $78
3-Chloroisonicotinic Acid >98.0%(GC)(T) C2983 25g $308
3-Chloroisonicotinic Acid C367378 5g $75
More product size

3-Chloroisonicotinic acid Properties

Melting point 227-231 °C (dec.)(lit.)
Boiling point 387.0±22.0 °C(Predicted)
Density 1.470±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form Solution
pka 0.12±0.25(Predicted)
color Brown to dark green to black
InChIKey MYAZXWFEMDJTFE-UHFFFAOYSA-N
CAS DataBase Reference 88912-27-0(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22
Safety Statements  36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29333999
NFPA 704
0
1 0

3-Chloroisonicotinic acid price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 633410 3-Chloropyridine-4-carboxylic acid 97% 88912-27-0 1g $31.7 2023-06-20 Buy
Sigma-Aldrich 633410 3-Chloropyridine-4-carboxylic acid 97% 88912-27-0 5g $38.4 2023-06-20 Buy
TCI Chemical C2983 3-Chloroisonicotinic Acid >98.0%(GC)(T) 88912-27-0 5g $78 2025-07-31 Buy
TCI Chemical C2983 3-Chloroisonicotinic Acid >98.0%(GC)(T) 88912-27-0 25g $308 2025-07-31 Buy
TRC C367378 3-Chloroisonicotinic Acid 88912-27-0 5g $75 2021-12-16 Buy
Product number Packaging Price Buy
633410 1g $31.7 Buy
633410 5g $38.4 Buy
C2983 5g $78 Buy
C2983 25g $308 Buy
C367378 5g $75 Buy

3-Chloroisonicotinic acid Chemical Properties,Uses,Production

Synthesis

3-Chloropyridine

626-60-8

3-Chloroisonicotinic acid

88912-27-0

A. Synthesis of 3-chloro-N-(4-chlorophenyl)pyridine-4-carboxamide. At -78 °C, 3-chloropyridine (1.00 mL, 10.5 mmol) was dissolved in THF and a freshly prepared lithium diisopropylammonium THF solution [prepared by the reaction of butyl lithium (7.21 mL, 11.5 mmol) with diisopropylamine (11.5 mmol)] was slowly added. After 0.25 h of reaction, carbon dioxide gas was passed into the mixture and slowly warmed to room temperature. After completion of the reaction, the mixture was concentrated and subsequently partitioned between EtOAc and water. The aqueous layer was washed twice with EtOAc. The pH of the aqueous layer was adjusted to about 3 by adding 1N HCl and extracted three more times with EtOAc. The organic phases were combined, dried with magnesium sulfate and concentrated. The residue was recrystallized by EtOAc to give 200 mg (12% yield) of 3-chloroisonicotinic acid.

References

[1] Patent: US6610704, 2003, B1

3-Chloroisonicotinic acid Preparation Products And Raw materials

Global( 215)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
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career henan chemical co
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Neostar United (Changzhou) Industrial Co., Ltd.
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View Lastest Price from 3-Chloroisonicotinic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Chloroisonicotinic acid  pictures 2025-11-18 3-Chloroisonicotinic acid
88912-27-0
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
3-Chloroisonicotinic acid pictures 2019-07-06 3-Chloroisonicotinic acid
88912-27-0
US $1.00 / kg 1kg 99% Customized Career Henan Chemical Co

3-Chloroisonicotinic acid Spectrum

3-Chloro-4-pyridinecarboxylic acid, 3-Chloroisonicotinic acid 4-Pyridinecarboxylic acid, 3-chloro- 3-Chloropyridine-4-carboxylic acid, 4-Carboxy-3-chloropyridine 3- chlorineisonicotinic acid 3-Chloropyridine-4-carboxylic acid 97% 3-Chloropyridine-4-carboxylic Acid, 97+% 3-CHLOROISONICOTINIC ACID 3-CHLOROPYRIDINE-4-CARBOXYLIC ACID 3-CHLORO-4-PYRIDINECARBOXYLIC ACID 3-Chloro-4-pyridine carboxlic acid 3-Chloropyridin-4-ylcarboxylic acid 3-Chloroisonicotinic Acid > 3-Chloroisonicotinic acid ISO 9001:2015 REACH 88912-27-0 Building Blocks Heterocyclic Building Blocks Halogenated Heterocycles Pyridines Pyridines Pyridine pharmacetical Building Blocks Carboxy