ChemicalBook >> CAS DataBase List >>S 18986
S 18986
- CAS No.
- 175340-20-2
- Chemical Name:
- S 18986
- Synonyms
- S 18986;(3aS)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide;1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aS)-
- CBNumber:
- CB62565929
- Molecular Formula:
- C10H12N2O2S
- Molecular Weight:
- 224.28
- MDL Number:
- MFCD00952956
- MOL File:
- 175340-20-2.mol
- MSDS File:
- SDS
Last updated:2025-04-17 18:22:24
| Boiling point | 399.9±45.0 °C(Predicted) |
|---|---|
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble to 50 mM in DMSO |
| form | Powder |
| pka | 9.88±0.20(Predicted) |
| color | White to light yellow |
| FDA UNII | IA262432Y9 |
| UNSPSC Code | 12352200 |
S 18986 price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 5.04983 | S18986 - CAS 175340-20-2 - Calbiochem | 175340-20-2 | 5MG | $246 | 2023-01-07 | Buy |
| Cayman Chemical | 14937 | S18986 ≥98% | 175340-20-2 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 14937 | S18986 ≥98% | 175340-20-2 | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 14937 | S18986 ≥98% | 175340-20-2 | 10mg | $214 | 2024-03-01 | Buy |
| Cayman Chemical | 14937 | S18986 ≥98% | 175340-20-2 | 25mg | $456 | 2024-03-01 | Buy |
S 18986 Chemical Properties,Uses,Production
Uses
S 18986 is a novel cognitive enhancer.
Biological Activity
Primary Target
AMPA', 'Reversible: yes
in vivo
S 18986 is robust memory-enhancing effects in middle-aged animals compared with aged ones. S 18986 shows antiamnesic properties in middle-aged rodents in spatial memory models [1].
S 18986 (5-50 mg/kg; i.p.) significantly increases both the induction and the maintenance of 4 and 20 bursts tetanus-evoked potentiation[1].
| Animal Model: | Middle-aged (14-15-months-old) mice[1] |
| Dosage: | 0.3, 1, and 10 mg/kg |
| Administration: | p.o. |
| Result: | Showed antiamnesic properties in middle-aged rodents. |
S 18986 Preparation Products And Raw materials
Raw materials
Preparation Products
S 18986 Suppliers
Global( 44)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3512 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| PURE SYNMR INGREDIENTS LIMITED | 021-26015538 | sven_shi@puresynmr.com | China | 50 | 50 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
S 18986
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aS)-
(3aS)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide
175340-20-2