ChemicalBook >> CAS DataBase List >>1-(3-Methoxypropyl)-4-piperidinamine

1-(3-Methoxypropyl)-4-piperidinamine

CAS No.
179474-79-4
Chemical Name:
1-(3-Methoxypropyl)-4-piperidinamine
Synonyms
Prucalopride intermediateB;4-AMino-1-(3-Methoxypropy...;Prucalopride Succinate iMpuritO;3-methoxy propyl piperidinamine;1-(3-methoxypropyl) -4-piperidine;1-(3-Methoxypropyl)-4-piperidimine;1-(3-Methoxypropyl)-4-piperidinamine;1-(3-Methoxypropyl)piperidin-4-aMine;Prucalopride Succinate interMediate B;4-AMino-1-(3-Methoxypropyl)piperidine
CBNumber:
CB62589756
Molecular Formula:
C9H20N2O
Molecular Weight:
172.27
MDL Number:
MFCD11104531
MOL File:
179474-79-4.mol
MSDS File:
SDS
Last updated:2024-07-09 21:58:15

1-(3-Methoxypropyl)-4-piperidinamine Properties

Boiling point 249℃
Density 0.946
Flash point 105℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Oil
pka 10.49±0.20(Predicted)
color Colourless to Pale Yellow
InChI InChI=1S/C9H20N2O/c1-12-8-2-5-11-6-3-9(10)4-7-11/h9H,2-8,10H2,1H3
InChIKey HIXAJGFVNMKLML-UHFFFAOYSA-N
SMILES N1(CCCOC)CCC(N)CC1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

1-(3-Methoxypropyl)-4-piperidinamine price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific Y1133 1-(3-methoxypropyl)piperidin-4-amine 179474-79-4 1g $95 2021-12-16 Buy
AK Scientific Y1133 1-(3-methoxypropyl)piperidin-4-amine 179474-79-4 10g $236 2021-12-16 Buy
Matrix Scientific 115680 4-Amino-1-(3-methoxypropyl)piperidine 95+% 179474-79-4 1g $572 2021-12-16 Buy
Matrix Scientific 115680 4-Amino-1-(3-methoxypropyl)piperidine 95+% 179474-79-4 5g $1580 2021-12-16 Buy
Matrix Scientific 115680 4-Amino-1-(3-methoxypropyl)piperidine 95+% 179474-79-4 10g $2222 2021-12-16 Buy
Product number Packaging Price Buy
Y1133 1g $95 Buy
Y1133 10g $236 Buy
115680 1g $572 Buy
115680 5g $1580 Buy
115680 10g $2222 Buy

1-(3-Methoxypropyl)-4-piperidinamine Chemical Properties,Uses,Production

Uses

1-(3-Methoxypropyl)-4-piperidinamine is a useful synthetic intermediate in the synthesis of Prucalopride Succinate (P838950); a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.

Synthesis

N-(1-(3-methoxypropyl)piperidin-4-yl)acetamide (10.72g, 0.05mol) was added to HCl-methanol solution (0.5M, 180ml), and the temperature was controlled at 2025°C After the reaction was detected, it was filtered, and the filter cake was washed with dichloromethane and dried to obtain 1-(3-Methoxypropyl)-4-piperidinamine with a yield of 96.4% and a purity of 99.7%.

519147-89-8
179474-79-4
Synthesis of 1-(3-Methoxypropyl)-4-piperidinamine from Prucalopride Impurity 11

1-(3-Methoxypropyl)-4-piperidinamine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 165)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Innopharm Industrial Co., Ltd.
+86-21-59960785 +86-17701845089 sales@hoyaopharm.com China 314 58
Hefei TianRui Pharmaceutical Chemical Co., Ltd.
+86-0551-68665055 +86-+86-18616906106 sales@trywchem.com China 129 58
Sach biotech Co.,Ltd
+8615888865902 sales@hzsqchem.com China 26 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20361 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29798 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21676 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32760 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29901 58
Jinan Shengqi pharmaceutical Co,Ltd
86+18663751872 christine@shengqipharm.com CHINA 491 58

View Lastest Price from 1-(3-Methoxypropyl)-4-piperidinamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(3-Methoxypropyl)-4-piperidinamine pictures 2024-07-09 1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
US $0.00-0.00 / KG 1KG 98% 800KGS/month Sach biotech Co.,Ltd
	1-(3-Methoxypropyl)-4-piperidinamine pictures 2024-03-29 1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
US $6.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
1-(3-Methoxypropyl)-4-piperidinamine pictures 2019-07-06 1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
US $100.00 / KG 1KG 98% 100KG Career Henan Chemical Co

1-(3-Methoxypropyl)-4-piperidinamine Spectrum

1-(3-Methoxypropyl)-4-piperidinamine 4-AMino-1-(3-Methoxypropyl)piperidine 4-AMino-1-(3-Methoxypropy... 4-PiperidinaMine, 1-(3-Methoxypropyl)- 1-(3-Methoxypropyl)piperidin-4-aMine Prucalopride Succinate interMediate B 1-(3-Methoxypropyl)-4-piperidimine Prucalopride intermediateB 1-(3-Methoxypropyl)-4-piperidinamine (Plucabili impurity) PRUCALOPRIDE SUCCINATE CAS 179474-85-2 INTERMEDIATES Prucalopride Succinate iMpuritO 3-methoxy propyl piperidinamine 1-(3-methoxypropyl) -4-piperidine 1- (3-methoxypropyl) -4-piperidine amine 179474-79-4 179474-97-4