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1-(3-Methoxypropyl)-4-piperidinamine

1-(3-Methoxypropyl)-4-piperidinamine structure

CAS No.: 179474-79-4

Chemical Name:: 1-(3-Methoxypropyl)-4-piperidinamine

Synonyms: Prucalopride intermediateB;4-AMino-1-(3-Methoxypropy...;Prucalopride Succinate iMpuritO;3-methoxy propyl piperidinamine;1-(3-Methoxypropyl)-4-piperidimine;1-(3-Methoxypropyl)-4-piperidinamine;1-(3-Methoxypropyl)piperidin-4-aMine;Prucalopride Succinate interMediate B;4-AMino-1-(3-Methoxypropyl)piperidine;4-PiperidinaMine, 1-(3-Methoxypropyl)-

CBNumber:: CB62589756

Molecular Formula:: C9H20N2O

Molecular Weight:: 172.27

MDL Number:: MFCD11104531

MOL File:: 179474-79-4.mol

MSDS File:: SDS

Modify Date:2023-05-15

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1-(3-Methoxypropyl)-4-piperidinamine Properties

Boiling point	249℃
Density	0.946
Flash point	105℃
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Oil
pka	10.49±0.20(Predicted)
color	Colourless to Pale Yellow
InChI	InChI=1S/C9H20N2O/c1-12-8-2-5-11-6-3-9(10)4-7-11/h9H,2-8,10H2,1H3
InChIKey	HIXAJGFVNMKLML-UHFFFAOYSA-N
SMILES	N1(CCCOC)CCC(N)CC1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338

1-(3-Methoxypropyl)-4-piperidinamine price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AK Scientific	Y1133	1-(3-methoxypropyl)piperidin-4-amine	179474-79-4	1g	$95	2021-12-16	Buy
AK Scientific	Y1133	1-(3-methoxypropyl)piperidin-4-amine	179474-79-4	10g	$236	2021-12-16	Buy
Matrix Scientific	115680	4-Amino-1-(3-methoxypropyl)piperidine 95+%	179474-79-4	1g	$572	2021-12-16	Buy
Matrix Scientific	115680	4-Amino-1-(3-methoxypropyl)piperidine 95+%	179474-79-4	5g	$1580	2021-12-16	Buy
Matrix Scientific	115680	4-Amino-1-(3-methoxypropyl)piperidine 95+%	179474-79-4	10g	$2222	2021-12-16	Buy

Product number	Packaging	Price	Buy
Y1133	1g	$95	Buy
Y1133	10g	$236	Buy
115680	1g	$572	Buy
115680	5g	$1580	Buy
115680	10g	$2222	Buy

1-(3-Methoxypropyl)-4-piperidinamine Chemical Properties,Uses,Production

Uses

1-(3-Methoxypropyl)-4-piperidinamine is a useful synthetic intermediate in the synthesis of Prucalopride Succinate (P838950); a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.

Synthesis

N-(1-(3-methoxypropyl)piperidin-4-yl)acetamide (10.72g, 0.05mol) was added to HCl-methanol solution (0.5M, 180ml), and the temperature was controlled at 2025°C After the reaction was detected, it was filtered, and the filter cake was washed with dichloromethane and dried to obtain 1-(3-Methoxypropyl)-4-piperidinamine with a yield of 96.4% and a purity of 99.7%.

1-(3-Methoxypropyl)-4-piperidinamine synthesis

Synthesis of 1-(3-Methoxypropyl)-4-piperidinamine from Prucalopride Impurity 11

1-(3-Methoxypropyl)-4-piperidinamine Preparation Products And Raw materials

Raw materials

Prucalopride Impurity 11

Preparation Products

1-(3-Methoxypropyl)-4-piperidinamine Suppliers

Global( 147)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Innopharm Industrial Co., Ltd.	+86-21-59960785 +86-17701845089	sales@hoyaopharm.com	China	259	58
Hefei TianRui Pharmaceutical Chemical Co., Ltd.	+86-0551-68665055 +86-+86-18616906106	sales@trywchem.com	China	110	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29810	60
Henan DaKen Chemical CO.,LTD.	+86-371-66670886	info@dakenchem.com	China	18267	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21975	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	31813	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29922	58
Jinan Shengqi pharmaceutical Co,Ltd	86+18663751872	christine@shengqipharm.com	CHINA	491	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58

Supplier	Advantage
Shanghai Innopharm Industrial Co., Ltd.	58
Hefei TianRui Pharmaceutical Chemical Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Henan DaKen Chemical CO.,LTD.	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Shengqi pharmaceutical Co,Ltd	58
Accela ChemBio Inc.	58

View Lastest Price from 1-(3-Methoxypropyl)-4-piperidinamine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-03-11	1-(3-Methoxypropyl)-4-piperidinamine 179474-79-4	US $10.00-15.00 / g	10g	99%	10t	Shanghai CRM New Material Technology Co., LTD
2019-07-06	1-(3-Methoxypropyl)-4-piperidinamine 179474-79-4	US $7.00 / kg	1kg	99%	100kg	Career Henan Chemical Co
2019-07-06	1-(3-Methoxypropyl)-4-piperidinamine 179474-79-4	US $100.00 / KG	1KG	98%	100KG	Career Henan Chemical Co

1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
US $10.00-15.00 / g
99%
Shanghai CRM New Material Technology Co., LTD

1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
US $7.00 / kg
99%
Career Henan Chemical Co

1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
US $100.00 / KG
98%
Career Henan Chemical Co

1-(3-Methoxypropyl)-4-piperidinamine Spectrum

1-(3-Methoxypropyl)-4-piperidinamine(179474-79-4)¹HNMR

1-(3-Methoxypropyl)-4-piperidinamine 4-AMino-1-(3-Methoxypropyl)piperidine 4-AMino-1-(3-Methoxypropy... 4-PiperidinaMine, 1-(3-Methoxypropyl)- 1-(3-Methoxypropyl)piperidin-4-aMine Prucalopride Succinate interMediate B 1-(3-Methoxypropyl)-4-piperidimine Prucalopride intermediateB 1-(3-Methoxypropyl)-4-piperidinamine (Plucabili impurity) PRUCALOPRIDE SUCCINATE CAS 179474-85-2 INTERMEDIATES Prucalopride Succinate iMpuritO 3-methoxy propyl piperidinamine 179474-79-4 179474-97-4