1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal
- CAS No.
- 474922-84-4
- Chemical Name:
- 1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal
- Synonyms
- 16:0 PEG1000 PE;16:0 PEG2000 PE;16:0 PEG5000 PE;16:0 PEG3000 PE;16:0 PEG PE, MW 350;DipalmitoylphosphatidylethanolamineN-[methoxy(polyethylene glycol)-2000];1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal;1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt);alpha-[(9R)-6-Hydroxy-6-oxido-1,12-dioxo-9-[(1-oxohexadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphaheptacos-1-yl]-omega-methoxypoly(oxy-1,2-ethanediyl) ammonium salt
- CBNumber:
- CB62602464
- Molecular Formula:
- (C2H4O)n.C39H76NO10P.NH3
- Molecular Weight:
- 0
- MDL Number:
- MFCD02262261
- MOL File:
- Mol file
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Chemical Properties,Uses,Production
Description
16:0 PEG PE, MW 1,100 is a PEG-modified phospholipid conjugate used in liposome formation of sterically stabilized liposomes with low reticuloendothelial system uptake and increased circulation duration to target cells.
Uses
16:0 PEG3000 PE is suitable for the preparation of liposome and advanced drug delivery nano liposomal system.
Uses
16:0 PEG5000 PE or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in preparation of lipid bilayer. It has also been used in liposome preparation.
Uses
16:0 PEG2000 PE, or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been used in liposome preparation. It has also been used in preparation of tripeptide arginine-glycine-aspartic acid magnetoliposomes (RGD-MLPs) and poly(ethylene glycol) (PEG)- MLPs.
General Description
16:0 PEG5000 PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 (DPPE-PEG 5000), is a mPEG phospholipid conjugate. Poly(ethylene glycol) (PEG)-based liposomal formulations are widely used in preparation of biocompatible self-assembled drug-delivery systems. These systems have an ability to escape the recognition and uptake by cells in the immune system at the same time it extends the residence time of the liposomes and allows continuous drug release into the targeted cells.
Biochem/physiol Actions
Polyethylene glycol (PEG) conjugated phospholipids are useful in liposome formulation for maintaining their stereochemistry. They also serve as drug carriers. PEGylated lipids aid in the formation of mixed micelles at high concentration.
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Preparation Products And Raw materials
Raw materials
Preparation Products
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9900 | 58 | |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Shochem(Shanghai)Co.,Ltd | +86-021-51783479 +86-13816874662 | info@shochem.com | China | 307 | 58 |
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
Guangzhou Weihua Biotechnology Co., Ltd | 020-020-37239396 18922492046 | weihuasw@foxmail.com | China | 2198 | 58 |
Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18306209933 | joyce@highfine.com | China | 1392 | 58 |
Shanghai Easy CDMO Co.,Ltd | 021-61734564 | August@easycdmo.com | China | 10010 | 58 |
Shochem (Shanghai) Co.,Ltd | 13611745246 13816874662 | sales@shochem.com | China | 540 | 58 |