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ChemicalBook >> CAS DataBase List >>5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Structure
5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile structure
CAS No.
330792-70-6
Chemical Name:
5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
Synonyms
IbrutinibN-3;Ibrutinib intermediate3;Zanubrutinib Impurity 8;Zanubrutinib impurity-20;Ibrutinib intermediates N-3;Zanubrutinib Related Compound 6;3-AMino-4-cyano-5-(4-phenoxyphenyl)pyrazole;3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile;3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile;5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
CBNumber:
CB62604963
Molecular Formula:
C16H12N4O
Molecular Weight:
276.29
MDL Number:
MFCD20270361
MOL File:
330792-70-6.mol
Last updated:2024-04-18 11:03:49
Request For Quotation

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Properties

Boiling point 585.3±50.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
refractive index 1.699
Flash point 307.8℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly)
pka 10.83±0.50(Predicted)
LogP 3.25298

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A603990 3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole 330792-70-6 100mg $165 2021-12-16 Buy
TRC A603990 3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole 330792-70-6 1g $1320 2021-12-16 Buy
ChemScene CS-M2596 1H-Pyrazole-4-carbonitrile,3-amino-5-(4-phenoxyphenyl)- 99.89% 330792-70-6 10g $165 2021-12-16 Buy
American Custom Chemicals Corporation CHM0390612 5-AMINO-3-(4-PHENOXYPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 95.00% 330792-70-6 5MG $496.69 2021-12-16 Buy
ChemScene CS-M2596 1H-Pyrazole-4-carbonitrile,3-amino-5-(4-phenoxyphenyl)- 99.89% 330792-70-6 25g $340 2021-12-16 Buy
Product number Packaging Price Buy
A603990 100mg $165 Buy
A603990 1g $1320 Buy
CS-M2596 10g $165 Buy
CHM0390612 5MG $496.69 Buy
CS-M2596 25g $340 Buy

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Chemical Properties,Uses,Production

Chemical Properties

Light yellow to off-white powder.

Uses

3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole has been used as a reactant in the preparation of ring-fused pyrazole derivatives to be used a inhibitors of lymphocyte-specific kinase (Lck)

Application

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is an intermediate of Ibrutinib (PCI-32765). it is a heterocyclic intermediate that typically used in the preparation of ACP-196, a selective second-generation BTK inhibitor.

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile synthesis

330792-69-3
330792-70-6
Synthesis of 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile from Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]-

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Preparation Products And Raw materials

Raw materials

4-PHENOXYBENZOYL CHLORIDE Propanedinitrile, 2-[hydroxy(4-phenoxyphenyl)Methylene]- Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]- Methyl 4-iodobenzoate 4-PHENOXYBENZOIC ACID
4-Phenoxybenzoic acid methyl ester Phenol Malononitrile

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Preparation Products

3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Suppliers

Global( 182)Suppliers
Supplier Tel Email Country ProdList Advantage
SyncoZymes (Shanghai) Co., Ltd.,
+86-021-68187180-811 +86-13681683526 lchen@syncozymes.com China 188 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
Jinan Jianfeng Chemical Co., Ltd 		0531-88110457; +8615562555968 info@pharmachemm.com China 222 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shanghai Yingrui Biopharma Co.,Ltd 		21-33585366 export01@shyrchem.com CHINA 1320 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
Supplier Advantage
SyncoZymes (Shanghai) Co., Ltd.,
58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Yingrui Biopharma Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Jinan Jianfeng Chemical Co., Ltd 		58
Chongqing Chemdad Co., Ltd 		58
Shanghai Yingrui Biopharma Co.,Ltd 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58

View Lastest Price from 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile pictures 2024-04-29 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
330792-70-6
 US $10.00-3.00 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile pictures 2023-12-28 5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
330792-70-6
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile pictures 2022-09-08 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
330792-70-6
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

330792-70-6(5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile)Related Search:

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5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile 3-AMino-4-cyano-5-(4-phenoxyphenyl)pyrazole 1H-Pyrazole-4-carbonitrile, 3-aMino-5-(4-phenoxyphenyl)- 3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile Ibrutinib intermediates N-3 Zanubrutinib Related Compound 6 Zanubrutinib Impurity 8 Ibrutinib intermediate3 IbrutinibN-3 CAS330792-70-6 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Zanubrutinib KSM-II : (4-isocyano-3-(4-phenoxyphenyl)-1H-pyrazol-5-amine) Zanubrutinib impurity-8 (3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole Zanubrutinib impurity-20 330792-70-6 330790-70-6 330792-70-6