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ML 161

ML 161 Structure
ML 161 structure
CAS No.
423735-93-7
Chemical Name:
ML 161
Synonyms
ML 161;CS-1106;Parmodulin 2;ML161, >=98%;ML161;ML-161;ML161 (Parmodulin 2);2-Bromo-N-(3-butanamidophenyl)benzamide;2-BroMo-N-(3-butyraMidophenyl)benzaMide;2-BroMo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide;Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-
CBNumber:
CB62629267
Molecular Formula:
C17H17BrN2O2
Molecular Weight:
361.23
MDL Number:
MFCD03063772
MOL File:
423735-93-7.mol
Last updated:2023-05-18 11:31:16
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ML 161 Properties

Boiling point 465.7±30.0 °C(Predicted)
Density 1.441±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble5mg/mL (clear solution)
pka 12.37±0.70(Predicted)
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS09
Signal word  Warning
Hazard statements  H410
Precautionary statements  P273-P501
RIDADR  UN 3077 9 / PGIII
WGK Germany  3

ML 161 price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0418 ML-161 ≥98% (HPLC) 423735-93-7 5mg $111 2024-03-01 Buy
Sigma-Aldrich SML0418 ML-161 ≥98% (HPLC) 423735-93-7 25mg $347 2024-03-01 Buy
Cayman Chemical 15179 ML-161 ≥95% 423735-93-7 1mg $32 2024-03-01 Buy
Cayman Chemical 15179 ML-161 ≥95% 423735-93-7 5mg $86 2024-03-01 Buy
Cayman Chemical 15179 ML-161 ≥95% 423735-93-7 10mg $153 2024-03-01 Buy
Product number Packaging Price Buy
SML0418 5mg $111 Buy
SML0418 25mg $347 Buy
15179 1mg $32 Buy
15179 5mg $86 Buy
15179 10mg $153 Buy

ML 161 Chemical Properties,Uses,Production

Description

ML-161 is an allosteric, reversible inhibitor of proteinase-activated receptor 1 (PAR1) on platelets, preventing surface expression of P-selectin induced by the peptide SFLLRN with an IC50 value of 0.26 μM. It blocks platelet activation induced by thrombin as well as by SFLLRN but not by PMA , U-46619 , or collagen.

Uses

ML 161 is a diaminobenzene derivative that acts as a selective inhibitor of platelet activation at protease-activated receptor 1 (PAR1). ML 161 has also been shown to inhibit thrombin-induced platelet activation.

Uses

ML 161 is a diaminobenzene derivative that acts as a selective inhibitor of platelet activation at protease-activated receptor 1 (PAR1). ML 161 has also been shown to inhibit thrombin-induced platelet activation.

Definition

ChEBI: 2-bromo-N-[3-(1-oxobutylamino)phenyl]benzamide is a member of benzamides.

References

[1]. dockendorff, c., et al., discovery of 1,3-diaminobenzenes as selective inhibitors of platelet activation at the par1 receptor. acs med chem lett, 2012. 3(3): p. 232-237.
[2]. verplank, l., et al., chemical genetic analysis of platelet granule secretion-probe 3, in probe reports from the nih molecular libraries program. 2010, national center for biotechnology information (us): bethesda (md).

ML 161 synthesis

99-09-2
423735-93-7
Synthesis of ML 161 from 3-Nitroaniline

ML 161 Preparation Products And Raw materials

Raw materials

N-(3-nitrophenyl)butanamide N-(3-AMINOPHENYL)BUTANAMIDE 3-Nitroaniline 2-Bromobenzoic acid

Preparation Products

ML 161 Suppliers

Global( 91)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
InvivoChem 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58

View Lastest Price from ML 161 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ML 161 pictures 2019-09-04 ML 161
423735-93-7
 US $5.00 / KG 1KG 99% 1ton Career Henan Chemical Co
  • ML 161 pictures
  • ML 161
    423735-93-7
  • US $5.00 / KG
  • 99%
  • Career Henan Chemical Co

ML 161 Spectrum

ML 161(423735-93-7)1HNMR

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ML 161 2-BroMo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide 2-BroMo-N-(3-butyraMidophenyl)benzaMide Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]- ML 161 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide ML161;ML-161 ML161, >=98% Parmodulin 2 CS-1106 2-Bromo-N-(3-butanamidophenyl)benzamide ML161 (Parmodulin 2) 423735-93-7 Inhibitors