ChemicalBook >> CAS DataBase List >>3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile

3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile

3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile structure

CAS No.: 1092578-46-5

Chemical Name:: 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile

Synonyms: (3R,4S)-Tofacitinib;Tofacitinib-14;Tofacitib impurity A;Tofatinib Impurity A;Tofacitinib IMpurity E;RS-tofacitinib citirate;Tofacitinib Impurity A(3R,4S);Azilsartan medoxomil impurity340;Tofacitinib Impurity A (3R,4S)-Tofacitinib;(3R,4S)-Tofacitinib (Tofacitinib Impurity)

CBNumber:: CB62642729

Molecular Formula:: C16H20N6O

Molecular Weight:: 312.3696

MDL Number:: MFCD23160057

MOL File:: 1092578-46-5.mol

Last updated:2023-05-18 11:31:17

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3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile Properties

Melting point	>108°C (dec.)
Density	1.296
storage temp.	Refrigerator
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	6.04±0.60(Predicted)
color	Pale Yellow to Yellow
FDA UNII	B64WR5WNB7

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H302-H360
Precautionary statements	P201-P202-P264-P270-P281-P301+P312-P308+P313-P330-P405-P501

3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	T528000	(3R,4S)-Tofacitinib	1092578-46-5	2.5mg	$305	2021-12-16	Buy
TRC	T528000	(3R,4S)-Tofacitinib	1092578-46-5	10mg	$790	2021-12-16	Buy
Medical Isotopes, Inc.	42411	(3R,4S)-Tofacitinib	1092578-46-5	1mg	$290	2021-12-16	Buy
Crysdot	CD31004611	(3R,4S)-Tofacitinib 98+%	1092578-46-5	5mg	$1628	2021-12-16	Buy

Product number	Packaging	Price	Buy
T528000	2.5mg	$305	Buy
T528000	10mg	$790	Buy
42411	1mg	$290	Buy
CD31004611	5mg	$1628	Buy

3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile Chemical Properties,Uses,Production

Uses

(3R,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.

Definition

ChEBI: (3r,4s)-Tofacitinib is a N-acylpiperidine.

3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile Preparation Products And Raw materials

Raw materials

Preparation Products

3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile Suppliers

Global( 95)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3149	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19994	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Standardpharm Co. Ltd.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
TargetMol Chemicals Inc.	58
Hangzhou Huarong Pharm Co., Ltd.	58
Labnetwork lnc.	58
China National Standard Pharmaceutical Corporation Limited	58

View Lastest Price from 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile 1092578-46-5	US $8.00 / KG	1KG	99%	10tons	Career Henan Chemical Co

3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile
1092578-46-5
US $8.00 / KG
99%
Career Henan Chemical Co

1092578-46-5(3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile)Related Search:

3-PiperidinaMine, 1-acetyl-N,4-diMethyl-N-1H-pyrrolo[2,3-d]pyriMidin-4-yl-, (3R,4R)- (9CI) 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE 3-((3S,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile Methyl (4-Methylpiperidin-3-yl)carbaMate 7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]-7-[(4-Met hylphenyl)sulfonyl]-

1-[2-(2-methoxyphenoxy)ethylamino]-3-(9-methylcarbazol-4-yl)oxypropan-2-ol:hydrochloride 3-METHOXYCARBONYLAMINO-4-METHYLPYRIDINE N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 13-Deoxyepirubicin Methyl (1-benzyl-4-Methylpiperidin-3-yl)carbaMate

N-((3S,4S)-1-benzyl-4-Methylpiperidin-3-yl)-N-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine 3-Amino-4-methylpyridine Tofacitinib Impurity 6 Tofacitinib Impurity 3 Tofacitinib Impurity 2

3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyriMidin-4-yl)(Methyl)aMino)-4-Methylpiperidin-1-yl)-3-oxopropanenitrile 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine

1of4

3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile 1-Piperidinepropanenitrile, 4-Methyl-3-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-β-oxo-, (3R,4S)- RS-tofacitinib citirate Tofacitinib IMpurity E Tofacitinib Impurity A(3R,4S) (3R,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile (3R,4S)-4-Methyl-3-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-beta-oxo-1-piperidinepropanenitrile Tofacitinib impurity 10/(3R,4S)-Tofacitinib/3-((3R,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino) piperidin-1-yl)-3-oxopropanenitrile Tofacitinib Impurity A (3R,4S)-Tofacitinib Tofacitinib-14 Tofacitib impurity A Azilsartan medoxomil impurity340 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitr (3R,4S)-Tofacitinib Tofatinib Impurity A 1-Piperidinepropanenitrile, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, (3R,4S)- (3R,4S)-Tofacitinib (Tofacitinib Impurity) (3R,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile 1092578-46-5