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Cinacalcet Impurity D

Cinacalcet Impurity D Structure
Cinacalcet Impurity D structure
CAS No.
1271930-15-4
Chemical Name:
Cinacalcet Impurity D
Synonyms
Cinacalcet USP RC B;CicalcetImpurity1HCl;CicalcetImpurityDHCl;cinacalcet iMpurity 8;Cinacalcet Impurity D;Cinacalcet Impurity D HCL;Cinacalcet tertiary amine;Cinacalcet USP Related Compound B;Cinacalcet Hydrochloride iMpuritX;Cinacalcet Impurity 5(Cinacalcet USP RC B)
CBNumber:
CB62671079
Molecular Formula:
C32H31F6N
Molecular Weight:
543.59
MDL Number:
MFCD27980107
MOL File:
1271930-15-4.mol
Last updated:2023-09-07 13:41:17
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Cinacalcet Impurity D Properties

Boiling point 552.2±50.0 °C(Predicted)
Density 1.203±0.06 g/cm3(Predicted)
pka 8.40±0.50(Predicted)
InChIKey BMWNEBVDXWCUKG-CRPMJUFNNA-N
SMILES C(N([C@@H](C1=C2C(C=CC=C2)=CC=C1)C)CCCC1=CC=CC(C(F)(F)F)=C1)CCC1=CC=CC(C(F)(F)F)=C1 |&1:2,r|

Cinacalcet Impurity D price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T791425 N-[(3-Trifluoromethyl)phenyl)propyl]Cinacalcet 1271930-15-4 50mg $1320 2021-12-16 Buy
Medical Isotopes, Inc. 53292 N-[(3-Trifluoromethyl)phenyl)propyl]Cinacalcet 1271930-15-4 50mg $2200 2021-12-16 Buy
Medical Isotopes, Inc. 53292 N-[(3-Trifluoromethyl)phenyl)propyl]Cinacalcet 1271930-15-4 5mg $650 2021-12-16 Buy
Product number Packaging Price Buy
T791425 50mg $1320 Buy
53292 50mg $2200 Buy
53292 5mg $650 Buy

Cinacalcet Impurity D Chemical Properties,Uses,Production

Description

Cinacalcet Impurity D is a potential byproduct or impurity in the synthesis of the drug. It is essential to study the properties and potential implications of Cinacalcet Impurity D for pharmaceutical research. Cinacalcet is a drug commonly used for the treatment of hyperparathyroidism in patients with chronic kidney disease.

Uses

N-[(3-Trifluoromethyl)phenyl)propyl] Cinacalcet (Cinacalcet USP Related Compound B) is an impurity of Cinacalcet Hydrochloride (C441800). Cinacalcet is used in clinical trial in secondary hyperparathyroidism.

Preparation

Cinacalcet hydrochloride (11 g, 0.028 mol) in toluene (150 mL) was added to potassium carbonate (7.74 g, 0.056 mol) followed by 1-(3-bromopropyl)-3-(trifluoromethyl)benzene (14.95 g, 0.056 mol) under stirring at 25-30 °C. The reaction was heated and stirred at 110-111 °C for 48 h. Upon completion of the reaction (by TLC), the reaction was cooled and quenched with water (100 mL). The organic layer was separated, washed with water (100 mL), and concentrated under reduced pressure to obtain a thick oil. The crude oil was then purified by column chromatography on silica gel by eluting with chloroform to afford Cinacalcet Impurity D as a thick transparent oil. Cinacalcet Impurity D

Cinacalcet Impurity D Preparation Products And Raw materials

Raw materials

Preparation Products

Cinacalcet Impurity D Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15185 58
Nanjing XiZe Biotechnology CO., Ltd. 025-58362220 15250997978 1511893459@qq.com China 7715 55
Tonichem Pharmaceutical Technology Co., Ltd. +86 (0752) 222-7171, +86 15815821171 China 1120 58
Roark Standards 0755-83552066 15986688328 service@roarkstandards.com China 1443 58
Supplier Advantage
BOC Sciences
58
Standardpharm Co. Ltd. 		58
sgtlifesciences pvt ltd 		58
China National Standard Pharmaceutical Corporation Limited 		58
Haoyuan Chemexpress Co., Ltd. 61
ChemStrong Scientific Co.,Ltd 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Nanjing XiZe Biotechnology CO., Ltd. 55
Tonichem Pharmaceutical Technology Co., Ltd. 58
Roark Standards 58

1271930-15-4(Cinacalcet Impurity D)Related Search:

N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide (αR)-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl)propyl]-1-napthaleneMethanaMine-N-oxide 1-NaphthaleneMethanaMine, 7,8-dihydro-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)- 1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride Cinacalcene Impurity I
Cinacalcet impurity C Cinacalcet Impurity 22 N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide Cinacalcet Impurity 21 (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoroMethyl)phenyl)propan-1-aMine
Cinacalcet IMpurity 6 Cinacalcet IMpurity 3 (E)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide Cinacalcet IMpurity 9 (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(M-tolyl)propan-1-aMine
N-(1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide 1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethan-1-amine hydrochloride Cinacalcet Impurity H

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cinacalcet iMpurity 8 1-NaphthaleneMethanaMine, α-Methyl-N,N-bis[3-[3-(trifluoroMethyl)phenyl]propyl]-, (αR)- (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)propan-1-amine N-[(3-Trifluoromethyl)phenyl)propyl] Cinacalcet N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]-N-[3-[3-(trifluoromethyl)phenyl]propyl]propan-1-amine Cinacalcet Impurity D HCL Cinacalcet USP RC B Cinacalcet Impurity 5(Cinacalcet USP RC B) "(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl) Cinacalcet USP Related Compound B Cinacalcet impurity 20/(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)propan-1-amine hydrochloride [(1R)-1-(naphthalen-1-yl)ethyl]bis({3-[3-(trifluoromethyl)phenyl]propyl})amine (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(2-(trifluoromethyl)phenyl)propan-1-amine hydrochloride (R)-(1-naphthalen-1-ylethyl)-N,N-bis[3-(3-trifluoromethylphenyl)propyl]amine, hydrogen chloride Cinacalcet Hydrochloride iMpuritX Cinacalcet Related Compund B (Cinacalcet Impurity D) Cinacalcet Impurity DQ: What is Cinacalcet Impurity D Q: What is the CAS Number of Cinacalcet Impurity D Q: What is the storage condition of Cinacalcet Impurity D Q: What are the applications of Cinacalcet Impurity D Cinacalcet tertiary amine CicalcetImpurity1HCl CicalcetImpurityDHCl 1-Naphthalenemethanamine, α-methyl-N,N-bis[3-[3-(trifluoromethyl)phenyl]propyl]-, (αR)- Cinacalcet Impurity D 1271930-15-4 C32H31F6N