(+/-)-EvodiaMine
- CAS No.
- 518-18-3
- Chemical Name:
- (+/-)-EvodiaMine
- Synonyms
- (+/-)-Evodiamine;(+/-)-Evodiamine>TXDUTHBFYKGSAH-UHFFFAOYSA-N;14-Methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one;14-Methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
- CBNumber:
- CB62673316
- Molecular Formula:
- C19H17N3O
- Molecular Weight:
- 303.36
- MDL Number:
- MFCD00016673
- MOL File:
- 518-18-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2939.80.0000 |
(+/-)-EvodiaMine price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | E1012 | (+/-)-Evodiamine >98.0%(HPLC)(N) | 518-18-3 | 1g | $137 | 2024-03-01 | Buy |
| TRC | E975133 | (+/-)-Evodiamine | 518-18-3 | 10mg | $45 | 2021-12-16 | Buy |
| Chem-Impex | 32473 | (±)-Evodiamine,98%(HPLC) 98%(HPLC) | 518-18-3 | 250MG | $56 | 2021-12-16 | Buy |
| Chem-Impex | 32473 | (±)-Evodiamine,98%(HPLC) 98%(HPLC) | 518-18-3 | 1G | $100.8 | 2021-12-16 | Buy |
| Chem-Impex | 32473 | (±)-Evodiamine,98%(HPLC) 98%(HPLC) | 518-18-3 | 5G | $476 | 2021-12-16 | Buy |
(+/-)-EvodiaMine Chemical Properties,Uses,Production
Description
Evodiamine is extracted and isolated from the fruit of Evodiarutaecarpa (Juss.) Benth., a rutaceae plant. It is converted into Isoevodiamine after being boiled with hydrochloric acid alcohol solution.
Definition
ChEBI: LSM-6483 is a member of beta-carbolines.
Pharmacokinetics
1. Antitumor activity
Evodiamine can inhibit the proliferation of various tumor cells, including cervical cancer, colon cancer, lung cancer, melanoma, T lymphocyte-like leukemia, prostate cancer Inhibition of proliferation of various tumor cells including cancer and breast cancer.
2. Anti-senile dementia effect
3. Effects on endocrine system
Evodiamine can inhibit 3β-hydroxysteroid dehydrogenase by reducing the activity of intracellular cyclic adenosine monophosphate (cAMP) related pathways (3β-HSD) and other steroid hormone production-related enzymes, reduce and affect the expression of signal transduction and RNA activation protein (StAR), and directly act on rat adrenal cortex reticulum cells to inhibit the secretion of corticosterone.
4. Weight loss and hypoglycemic effect
5.Anti-inflammatory and analgesic effect
6. Effects on the cardiovascular system
(+/-)-EvodiaMine Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)-EvodiaMine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24539 | 81 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28398 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23680 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23662 | 75 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22519 | 55 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15878 | 55 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20810 | 60 |
| Shandong Ono Chemical Co., Ltd. | 0539-6362799 20） | China | 10007 | 58 |