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5-Ethynyl-2'-deoxycytidine

5-Ethynyl-2'-deoxycytidine structure

CAS No.: 69075-47-4

Chemical Name:: 5-Ethynyl-2'-deoxycytidine

Synonyms: 5-Ethynyl-2'-dC;-Ethynyl-2’5-Ethynyl-2'-deoxycytidine;5-Ethynyl-2'-deoxycytidine;2'-Deoxy-5-ethynylcytidine;5-Ethynyl-2'-deoxycytidine>Cytidine, 2'-deoxy-5-ethynyl-;5-Ethynyl-2′-deoxycytidine, (EdC);5-Ethynyl-2'-deoxycytidine 69075-47-4;5-Ethynyl-2'-deoxycytidine, (EdC) AldrichCPR

CBNumber:: CB62682226

Molecular Formula:: C11H13N3O4

Molecular Weight:: 251.24

MDL Number:: MFCD22417249

MOL File:: 69075-47-4.mol

MSDS File:: SDS

Last updated:2023-06-08 17:06:35

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5-Ethynyl-2'-deoxycytidine Properties

Melting point	191 °C (decomp)(Solv: dichloromethane (75-09-2); methanol (67-56-1))
Boiling point	475.7±55.0 °C(Predicted)
Density	1.54±0.1 g/cm3(Predicted)
storage temp.	Store at 2-8°C, protect from light, stored under nitrogen
solubility	DMF: 5 mg/ml; DMSO: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
pka	14.03±0.60(Predicted)
form	powder to crystal
color	White to Light yellow to Light orange
λmax	292nm(H2O)(lit.)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
WGK Germany	3
HS Code	2934.99.4400

5-Ethynyl-2'-deoxycytidine price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T511307	5-Ethynyl-2′-deoxycytidine, (EdC) AldrichCPR	69075-47-4	5mg	$180	2024-03-01	Buy
TCI Chemical	E1093	5-Ethynyl-2'-deoxycytidine >98.0%(N)	69075-47-4	50mg	$203	2021-12-16	Buy
TCI Chemical	E1093	5-Ethynyl-2'-deoxycytidine >98.0%(N)	69075-47-4	200mg	$712	2024-03-01	Buy
Cayman Chemical	11581	5'-Ethynyl-2'-deoxycytidine ≥98%	69075-47-4	1mg	$32	2024-03-01	Buy
Cayman Chemical	11581	5'-Ethynyl-2'-deoxycytidine ≥98%	69075-47-4	5mg	$116	2024-03-01	Buy

Product number	Packaging	Price	Buy
T511307	5mg	$180	Buy
E1093	50mg	$203	Buy
E1093	200mg	$712	Buy
11581	1mg	$32	Buy
11581	5mg	$116	Buy

5-Ethynyl-2'-deoxycytidine Chemical Properties,Uses,Production

Description

5''-Ethynyl-2''-deoxycytidine (EdC) is a nucleoside analog that inhibits replication of the herpes simplex virus-1 (HSV-1) KOS strain (ID₅₀ = 0.2 μg/mL). It also reduces virus-induced cytopathogenicity of HSV-1, HSV-2, and vaccinia virus strains in PRK cells (MICs = 0.2-0.4, 1-2, and 5 μg/ml, respectively). EdC is an inhibitor of thymidylate synthetase, selectively reducing DNA incorporation of [1'',2''-³H]deoxyuridine over [CH₃-³H]deoxythymidine in PRK cells (ID₅₀s = 3 and 120 μg/ml, respectively). It inhibits thymidine synthetase in and reduces proliferation of L1210 cells, an effect which is reversed by addition of deoxythymidine (ID₅₀s = 4.4 and 1,000 μg/ml, respectively). EdC has been used to monitor DNA synthesis and cellular replication via click chemistry conjugation of the ethynyl group to an azido group of various fluorochromes.

Uses

5-Ethynyl-2’-deoxycytidine is an lower toxicity analog of 2’-deoxycytidine, a metabolic labeling probe for DNA synthesis. 5-Ethynyl-2’-deoxycytidine is most commonly used when thymidine analogs is undesirable.

Uses

A relatively nontoxic 2′-deoxycytidine analog for metabolic labeling of newly synthesized DNA in vivo. Especially suitable if the use of thymidine analogs is undesirable.

5-Ethynyl-2'-deoxycytidine Preparation Products And Raw materials

Raw materials

Preparation Products

5-Ethynyl-2'-deoxycytidine Suppliers

Global( 53)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Wuhan Fortuna Chemical Co., Ltd	+86-27-59207850 +86-13986145403	info@fortunachem.com	China	5988	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10026	58
Wuhu Nuowei chemistry Co., Ltd.	+86-0553-2911116-802 +undefined17756524438	sales1@nuowei-chem.com	China	1642	58
Henan Aochuang Chemical Co.,Ltd.	+86-0371-63689365 +8618638391208	sales@aochuangchem.com	China	9425	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58

Supplier	Advantage
Chongqing Chemdad Co., Ltd	58
career henan chemical co	58
Wuhan Fortuna Chemical Co., Ltd	58
BOC Sciences	58
NewCan Biotech Limited	58
Wuhu Nuowei chemistry Co., Ltd.	58
Henan Aochuang Chemical Co.,Ltd.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from 5-Ethynyl-2'-deoxycytidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-09-27	5-Ethynyl-2'-deoxycytidine 69075-47-4	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-09-29	5-Ethynyl-2'-deoxycytidine 69075-47-4	US $0.00-0.00 / g	10g	98%min	1000g	WUHAN FORTUNA CHEMICAL CO., LTD
2020-03-05	5-Ethynyl-2'-deoxycytidine 69075-47-4	US $1.00 / KG	1KG	98% HPLC	10 tons	Career Henan Chemical Co

5-Ethynyl-2'-deoxycytidine
69075-47-4
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

5-Ethynyl-2'-deoxycytidine
69075-47-4
US $0.00-0.00 / g
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

5-Ethynyl-2'-deoxycytidine
69075-47-4
US $1.00 / KG
98% HPLC
Career Henan Chemical Co

5-Ethynyl-2′-deoxycytidine, (EdC) Cytidine, 2'-deoxy-5-ethynyl- 2'-Deoxy-5-ethynylcytidine 5-Ethynyl-2'-deoxycytidine, (EdC) AldrichCPR 5-Ethynyl-2'-deoxycytidine 5-Ethynyl-2'-dC 4-Amino-5-ethynyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one -Ethynyl-2&rsquo 5-Ethynyl-2'-deoxycytidine> 5-Ethynyl-2'-deoxycytidine 69075-47-4 5-Ethynyl-2'-deoxycytidine 69075-47-4 Carbohydrates & Derivatives, Heterocycles, Nucleotides, Bases & Related Reagents