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ASPERULOSIDE

CAS No.
14259-45-1
Chemical Name:
ASPERULOSIDE
Synonyms
Nsc 31760;Asperulosid;ASPERULOSIDE;Einecs 238-137-5;RUBICHLORIC ACID;Asperuloside >=95% (LC/MS-ELSD);(2aS)-2a,4aα,5,7bα-Tetrahydro-4-acetoxymethyl-5α-(β-D-glucopyranosyloxy)-1H-2,6-dioxacyclopent[cd]inden-1-one;1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(β-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)-;1H-2,6-Dioxacyclopentcdinden-1-one, 4-(acetyloxy)methyl-5-(.beta.-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)-;1H-2,6-Dioxacyclopent(cd)inden-1-one, 4-((acetyloxy)methyl)-5-(beta-D-glucopyranosyloxy)-2A,4A,5,7B-tetrahydro-, (2as-(2aalpha,5alpha,7balpha))-
CBNumber:
CB6272515
Molecular Formula:
C18H22O11
Molecular Weight:
414.36
MDL Number:
MFCD31725921
MOL File:
14259-45-1.mol
Last updated:2023-05-18 11:31:08

ASPERULOSIDE Properties

Melting point 131-132°
alpha D25 -198.6° (c = 1.44 in water)
Boiling point 704.2±60.0 °C(Predicted)
Density 1.62±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in methanol and water
form powder
pka 12.76±0.70(Predicted)
color White
FDA UNII V3CFI02X39
EPA Substance Registry System 1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(?-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)- (14259-45-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3

ASPERULOSIDE price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SMB00085 Asperuloside ≥95% (LC/MS-ELSD) 14259-45-1 1mg $303 2024-03-01 Buy
Sigma-Aldrich PHL83229 Asperuloside phyproof Reference Substance 14259-45-1 10mg $574 2024-03-01 Buy
Cayman Chemical 29439 Asperuloside 14259-45-1 5mg $382 2024-03-01 Buy
Cayman Chemical 29439 Asperuloside 14259-45-1 10mg $556 2024-03-01 Buy
Cayman Chemical 29439 Asperuloside 14259-45-1 1mg $139 2024-03-01 Buy
Product number Packaging Price Buy
SMB00085 1mg $303 Buy
PHL83229 10mg $574 Buy
29439 5mg $382 Buy
29439 10mg $556 Buy
29439 1mg $139 Buy

ASPERULOSIDE Chemical Properties,Uses,Production

Description

Asperuloside is an iridoid glycoside that has been found in G. tunetanum and has diverse biological activities, including anti-angiogenic, anti-inflammatory, and anti-obesity properties. It reduces microvessel formation by 67% in a chick embryo chorioallantoic membrane assay when used at a concentration of 2 μg/egg. Asperuloside (20, 40, and 80 mg/L) inhibits LPS-induced increases in TNF-α, IL-1β, and IL-6 production in RAW 264.7 macrophages in a concentration-dependent manner. It reduces lung myeloperoxidase (MPO) activity and bronchoalveolar lavage fluid (BALF) levels of TNF-α, IL-1β, and IL-6 in a mouse model of LPS-induced acute lung injury when administered at doses of 20, 40, and 80 mg/kg. Dietary administration of asperuloside decreases body weight gain, white adipose tissue (WAT) weight, and the ratio of WAT weight to body weight in a high-fat diet-induced mouse model of metabolic syndrome.

Uses

Asperuloside is an iridoid found in Paederia foetida and is an inhibitor of xanthine oxidase and is used in the treatment of various disorders including inflammatory and cardiovascular diseases.

Definition

ChEBI: A iridoid monoterpenoid glycoside isolated from Galium verum.

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View Lastest Price from ASPERULOSIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Asperuloside pictures 2023-02-24 Asperuloside
14259-45-1
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
ASPERULOSIDE pictures 2020-01-13 ASPERULOSIDE
14259-45-1
US $9.80 / KG 1KG ≥98% 20 tons Career Henan Chemical Co
  • Asperuloside pictures
  • Asperuloside
    14259-45-1
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • ASPERULOSIDE pictures
  • ASPERULOSIDE
    14259-45-1
  • US $9.80 / KG
  • ≥98%
  • Career Henan Chemical Co
ASPERULOSIDE RUBICHLORIC ACID [2aS-(2aalpha,4aalpha,5alpha,7balpha)]-5-(beta-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-1-oxo-1H-2,6-dioxacyclopent[cd]inden-4-ylmethyl acetate 1H-2,6-Dioxacyclopentcdinden-1-one, 4-(acetyloxy)methyl-5-(.beta.-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)- (2aS)-2a,4aα,5,7bα-Tetrahydro-4-acetoxymethyl-5α-(β-D-glucopyranosyloxy)-1H-2,6-dioxacyclopent[cd]inden-1-one (2As-(2aalpha,4aalpha,5alpha,7balpha))-5-(beta-D-glucopyranosyloxy)-2A,4A,5,7B-tetrahydro-1-oxo-1H-2,6-dioxacyclopent(cd)inden-4-ylmethyl acetate 1H-2,6-Dioxacyclopent(cd)inden-1-one, 4-((acetyloxy)methyl)-5-(beta-D-glucopyranosyloxy)-2A,4A,5,7B-tetrahydro-, (2as-(2aalpha,5alpha,7balpha))- Einecs 238-137-5 Nsc 31760 Asperulosid 1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(β-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)- Asperuloside >=95% (LC/MS-ELSD) 14259-45-1 14529-45-1 Miscellaneous Natural Products