Dynasore hydrate

Dynasore hydrate structure

CAS No.: 1202867-00-2

Chemical Name:: Dynasore hydrate

Synonyms: Dynasore hydrate

CBNumber:: CB62750338

Molecular Formula:: C18H16N2O5

Molecular Weight:: 340.33004

MDL Number:: MFCD11045288

MOL File:: 1202867-00-2.mol

Last updated:2023-04-23 13:52:06

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Dynasore hydrate Properties

storage temp.	-20°C
solubility	DMSO: ≥10mg/mL
form	powder
color	off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS09
Signal word	Warning
Hazard statements	H400
Precautionary statements	P273
Hazard Codes	N
Risk Statements	50
Safety Statements	22-24/25-61
RIDADR	UN 3077 9 / PGIII
WGK Germany	3

Dynasore hydrate price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D7693	Dynasore hydrate	1202867-00-2	5mg	$120	2024-03-01	Buy
Sigma-Aldrich	D7693	Dynasore hydrate	1202867-00-2	25mg	$489	2024-03-01	Buy
American Custom Chemicals Corporation	INB0000994	DYNASORE HYDRATE 95.00%	1202867-00-2	10MG	$583	2021-12-16	Buy
American Custom Chemicals Corporation	INB0000994	DYNASORE HYDRATE 95.00%	1202867-00-2	0.025G	$768	2021-12-16	Buy
American Custom Chemicals Corporation	INB0000994	DYNASORE HYDRATE 95.00%	1202867-00-2	50MG	$1136	2021-12-16	Buy

Product number	Packaging	Price	Buy
D7693	5mg	$120	Buy
D7693	25mg	$489	Buy
INB0000994	10MG	$583	Buy
INB0000994	0.025G	$768	Buy
INB0000994	50MG	$1136	Buy

Dynasore hydrate Chemical Properties,Uses,Production

Uses

Dynasore hydrate has been used:

for priming fetal mesenchymal stem/stromal cells (fMSC)
in confocal microscopy
in wound healing/scratch and tube-formation assay
to analyse its effects on Coxsackievirus A9 (CAV9) infection
to inhibit clathrin-mediated endocytosis and caveolin-mediated endocytosis
in live imaging of cells

General Description

Dynasore is a small molecule GTPase inhibitor that targets dynamin-1, dynamin-2 and Drp1 (mitochondrial). Dynasore blocks dynamin-dependent endocytosis, scission of endocytic vesicles. Dynosore is profibrotic, induces PAI-1 in pleural mesothelial cells, and may be an effective pleurodesing (pleurodesis) agent. Dynasor blocks human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.
Dynasore hydrate lowers labile cholesterol in the plasma membrane and distorts lipid raft organization. Dynasore exhibits pleotropic effects on herpes simplex virus (HSV)-1 and HSV-2 infection. It hinders viral entry, trafficking of viral proteins and capsid formation.

Biochem/physiol Actions

Dynasore is a cell-permeable, reversible noncompetitive dynamin 1 and dynamin 2 GTPase activity inhibitor.

Dynasore hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Dynasore hydrate Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58

Supplier	Advantage
Sigma-Aldrich	80
Energy Chemical	58

Dynasore hydrate 1202867-00-2