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4-Nitrotoluene structure
Chemical Name:
PNT;4NT;nci9579;4-Nitrotol;NCI-C60537;'LGC' (2401);nitrotoluenos;p-Nitrotoluol;4-Nitrotoluol;p-nitro-toluen
Molecular Formula:
Formula Weight:
MOL File:

4-Nitrotoluene Properties

Melting point:
52-54 °C(lit.)
Boiling point:
238 °C(lit.)
1.392 g/mL at 25 °C(lit.)
vapor density 
4.7 (vs air)
vapor pressure 
5 mm Hg ( 85 °C)
refractive index 
Flash point:
223 °F
storage temp. 
Crystalline Solid
Specific Gravity
explosive limit
Water Solubility 
0.35 g/L (20 ºC)
Stability May be shock sensitive. Incompatible with sulfuric acid, strong bases, reducing agents, strong oxidizing agents.
CAS DataBase Reference
99-99-0(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-methyl-4-nitro-(99-99-0)
EPA Substance Registry System
Benzene, 1-methyl-4-nitro-(99-99-0)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  T,N,F,Xn
Risk Statements  23/24/25-33-51/53-36/37/38-11-36-20/21/22
Safety Statements  28-37-45-61-28A-27-16-36/37-26
RIDADR  UN 3446 6.1/PG 2
WGK Germany  2
RTECS  XT3325000
Autoignition Temperature 734 °F
HazardClass  6.1
PackingGroup  II
HS Code  29042000
Hazardous Substances Data 99-99-0(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 1960 mg/kg LD50 dermal Rat > 16000 mg/kg
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P309 IF exposed or if you feel unwell:
P310 Immediately call a POISON CENTER or doctor/physician.
P311 Call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P235 Store in a well-ventilated place. Keep cool.

NFPA 704

Diamond Hazard Value Description
Flammability   1 Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
Instability   1 Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene)

(NFPA, 2010)

4-Nitrotoluene price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N27322 4-Nitrotoluene 99% 99-99-0 100g $21.2 2018-11-13 Buy
Sigma-Aldrich N27322 4-Nitrotoluene 99% 99-99-0 1kg $58.9 2018-11-13 Buy
TCI Chemical N0276 4-Nitrotoluene >99.0%(GC) 99-99-0 25g $14 2018-11-22 Buy
TCI Chemical N0276 4-Nitrotoluene >99.0%(GC) 99-99-0 500g $32 2018-11-22 Buy
Sigma-Aldrich 8.06807 4-Nitrotoluene for synthesis. CAS 99-99-0, chemical formula 4-(NO )C H CH ., for synthesis 99-99-0 8068071000 $58.5 2018-11-23 Buy

4-Nitrotoluene Chemical Properties,Uses,Production

Chemical Properties

light yellow crystals

Chemical Properties

Nitrotoluene is formed in 3 isomeric forms. The o-and m-forms are yellow liquids or solids. The p-form is a pale yellow crystalline solid. All have weak aromatic odors. The Odor Thresholds are: 0.05 mg/L (o-isomer); 1.74 ppm (m-isomer).


manufacture of dyes, toluidines, nitrobenzoic acids, agricultural and rubber chemicals.

General Description

A yellow liquid with a weak aromatic odor. Toxic. Insoluble in water. Combustible but may take some effort to ignite. Produces toxic oxides of nitrogen when burned. In a spill, immediate steps should be taken to limit its spread to the environment. Can easily penetrate the soil and contaminate groundwater or nearby streams. Used to make other chemicals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4-Nitrotoluene may react violently with sodium, tetranitromethane, strong oxidizing agents , sulfuric acid and other acids.


Toxic by inhalation, ingestion, skin absorption. Methemoglobinemia. Questionable carcinogen.

Health Hazard

INHALATION, INGESTION, OR SKIN: Headache, flushed face, dizziness, dyspnea (difficult breathing), cyanosis, nausea, vomiting, muscular weakness, rapid pulse and respiration, irritability, and convulsions.

Fire Hazard

Special Hazards of Combustion Products: Yields toxic oxides of nitrogen when burning.

Safety Profile

A poison. Moderately toxic by ingestion, inhalation, and intraperitoneal routes. Mildly toxic by skin contact. Mutation data reported. Combustible when exposed to heat or flame. To fight fire, use CO2, dry chemical, foam. The residue from vacuum distillation may explode spontaneously. Reacts with sodmm to form an ignitable product. Violent reaction with concentrated sulfuric acid (above 16O°C), sulfuric acid + sulfur trioxide (above 52°C). Mixtures with tetranitromethane are sensitive high explosives. May explode on standing. It has been involved in plant scale explosions. When heated to decomposition it emits toxic fumes of NOx. See also other methylnitrobenzene entries and NITRO COMPOUNDS OF AROMATIC HYDROCARBONS.

Potential Exposure

The nitrotoluenes are used in the production of toluidines and other dye intermediates. All isomers are used in manufacture of agriculture and rubber chemicals and in various dyes.

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.


UN1664 Nitrotoluenes, (o-; m-; p-), Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Purification Methods

Dry it in air, then dry it in a vacuum desiccator over H2SO4. [Wright & Grilliom J Am Chem Soc 108 2340 1986, Beilstein 5 IV 848.]


Decomposes on contact with strong oxidizers; strong acids; reducing agents; strong bases; ammonia, amines producing toxic fumes, causing fire and explosion hazard. Heat above 190C may cause explosive decomposition. Attacks some plastics, rubbers, and coatings.

Waste Disposal

Controlled incineration-care must be taken to maintain complete combustion at all times. Incineration of large quantities may require scrubbers to control the emission of nitrogen oxides.

4-Nitrotoluene Preparation Products And Raw materials

Raw materials

Preparation Products

4-Nitrotoluene Suppliers

Global( 187)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hebei Guanlang Biotechnology Co., Ltd.
+86-0311-66562153 whatsapp +8615203118427
+86-0311-66562153 CHINA 407 50
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 CHINA 1367 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114 CHINA 6374 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24001 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930501651 CHINA 925 58
career henan chemical co
+86-371-86658258 CHINA 20331 58
Hebei Chisure Biotechnology Co., Ltd.
+8613292893290 CHINA 1020 58
Dalian Idery Biotechnology Co., Ltd. 0411-62696576/0411-66160116/15141125520
0411-66160116 China 87 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96519 76

View Lastest Price from 4-Nitrotoluene manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 4-Nitrotoluene
US $1.00 / kg 1kg 99% as request career henan chemical co
2018-07-27 4-Nitrotoluene
US $10.00 / KG 10G 99% 500kg/month Hebei Chisure Biotechnology Co., Ltd.
2018-08-13 4-Nitrotoluene
US $10.00 / KG 1KG 99% 100 MT per month Hebei Guanlang Biotechnology Co., Ltd.

4-Nitrotoluene Spectrum

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