Anti-Runt-related transcription factor 2 isoform 2
- CAS No.
- Chemical Name:
- Anti-Runt-related transcription factor 2 isoform 2
- Synonyms
- Anti-PN;Anti-CCD;Anti-PLF;Anti-AML3;Anti-OSF2;Anti-CCD1;Anti-CBFA1;Anti-POSTN;Anti-PEA2aA;Anti-PEBP2aA
- CBNumber:
- CB62898582
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD07370486
- MOL File:
- Mol file
Anti-Runt-related transcription factor 2 isoform 2 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4300696 | Anti-Postn antibody produced in rabbit affinity isolated antibody | 100μg | $511 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA012306 | Anti-POSTN antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB2101847 | Anti-POSTN antibody produced in rabbit affinity isolated antibody | 100μL | $503 | 2023-06-20 | Buy |
Anti-Runt-related transcription factor 2 isoform 2 Chemical Properties,Uses,Production
Uses
Anti-POSTN antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
Uses
Anti-POSTN antibody produced in rabbit has been used in western blot.
General Description
Periostin (POSTN) gene with 23 exons spanning 36 kb is mapped to chromosome 13q13.3. The gene codes for periostin, a matricellular protein that belongs to the family of non-structural matrix proteins. Periostin structure contains a signal peptide, four fasciclin-like domains (FAS1) with vitamin K-dependent γ-carboxyglutamic acid (Gla) residues, and hydrophilic C-terminal region with the heparin-binding site. The protein is mainly expressed in the periosteum, periodontal ligament, heart valves, and tendons. The antibody detects endogenous level of total periostin protein.
Biochem/physiol Actions
Periostin (POSTN) facilitates extracellular matrix structure and organization. It acts as a collagen chaperone and regulates type I collagen fibrillogenesis. POSTN is implicated in early stages of bone formation, tissue repair, and cell recruitment and adhesion. This protein is essential for cancer stem cell maintenance and metastasis. Increased expression of POSTN has been observed in various types of cancers including prostate, breast, lung, pancreatic, ovarian, and colorectal cancer. Hence, the postn levels can be used as a prognostic biomarker for these cancers.
Anti-Runt-related transcription factor 2 isoform 2 Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-Runt-related transcription factor 2 isoform 2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |