ChemicalBook >> CAS DataBase List >>R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE structure

CAS No.: 67287-39-2

Chemical Name:: R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

Synonyms: SKF 81297C;SKF-81297 HBr;R(+)-SKF-81297 HYDROBROMIDE;9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol:hydrobromide;(R)-6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide;R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

CBNumber:: CB6294186

Molecular Formula:: C16H17BrClNO2

Molecular Weight:: 370.67

MDL Number:: MFCD00671792

MOL File:: 67287-39-2.mol

Last updated:2023-06-30 15:45:59

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R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Properties

Melting point	>256°C (dec.)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	H₂O: 6 mg/mL
form	solid
color	white to off-white
FDA UNII	L86RFQ3NSD

SAFETY

Risk and Safety Statements

WGK Germany	3

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	15067	(±)-SKF 81297 (hydrobromide) ≥98%	67287-39-2	5mg	$97	2024-03-01	Buy
Cayman Chemical	15067	(±)-SKF 81297 (hydrobromide) ≥98%	67287-39-2	10mg	$145	2024-03-01	Buy
Cayman Chemical	15067	(±)-SKF 81297 (hydrobromide) ≥98%	67287-39-2	25mg	$218	2024-03-01	Buy
TRC	S550020	SKF81297C	67287-39-2	10mg	$100	2021-12-16	Buy
ApexBio Technology	B6744	SKF81297hydrobromide	67287-39-2	25mg	$247	2021-12-16	Buy

Product number	Packaging	Price	Buy
15067	5mg	$97	Buy
15067	10mg	$145	Buy
15067	25mg	$218	Buy
S550020	10mg	$100	Buy
B6744	25mg	$247	Buy

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties,Uses,Production

Uses

SKF 81297C is a dopamine D1 agonist (1).

Hazard

A poison.

Biological Activity

skf 81297 hydrobromide is a selective agonist of the dopamine d1-like receptor, with a ki value of 1.9 nm. the dopamine d1-like receptors, consisting of d1 and d5 subtypes, are a subfamily of dopamine receptors that mediate excitatory neurotransmission after binding the endogenous neurotransmitter dopamine. the dopamine d1-like receptors have been implicated in dopaminergic regulation of a variety of fundamental neurophysiologic processes including mood, motivation, cognitive function, as well as motor activity.1. neumeyer jl, kula ns, bergman j, baldessarini rj. receptor affinities of dopamine d1 receptor-selective novel phenylbenzazepines. european journal of pharmacology, 2003, 474(2-3): 137-140.2. undieh as. pharmacology of signaling induced by dopamine d(1)-like receptor activation. pharmacology & therapeutics, 2010, 128(1): 37-60.3. vermeulen rj, drukarch b, sahadat mc, et al. the dopamine d1 agonist skf 81297 and the dopamine d2 agonist ly 171555 act synergistically to stimulate motor behavior of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned parkinsonian rhesus monkeys. movement disorders, 1994, 9(6): 664-672.

storage

+4°C (desiccate)

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Suppliers

Global( 19)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
Shanghai Universal Biotech Co.,Ltd	18768175414	gaojun@univ-bio.com	China	24998	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Shanghai Tachizaki Biomedical Research Center	18014399201	sales@chemlab-tachizaki.com	China	2488	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
BOC Sciences	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
MedBioPharmaceutical Technology Inc	58
Energy Chemical	58
Changzhou Furuisi Biotechnology Co., Ltd	58
Shanghai Universal Biotech Co.,Ltd	58
TargetMol Chemicals Inc.	58
Shanghai Tachizaki Biomedical Research Center	58

67287-39-2(R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE)Related Search:

R(+)-6-CHLORO-7,8-DIHYDROXY-3-METHYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE (R)-6-CHLORO-2,3,4,5-TETRAHYDRO-1-(4-HYDROXYPHENYL)-1H-3-BENZAZEPINE-7,8-DIOL BROMIDE 1-PHENYL-2,3,4,5-TETRAHYDRO-1H-BENZAZEPINE (+/-)-SKF-38393 HYDROCHLORIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-OL R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE 2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol

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R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE R(+)-SKF-81297 HYDROBROMIDE (R)-6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide 9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol:hydrobromide SKF 81297C SKF-81297 HBr 67287-39-2