Alliin
- CAS No.
- 556-27-4
- Chemical Name:
- Alliin
- Synonyms
- ALLIIN;ALLIIN(P);(±)-Alliin;ALLIIN hplc;L(+) ALLIIN;(+)-L-Alliin;L(+/-) ALLIIN;Alliin (25 mg);Alliin556-27-4;Alliin/ACSO/SAC
- CBNumber:
- CB6301738
- Molecular Formula:
- C6H11NO3S
- Molecular Weight:
- 177.22
- MDL Number:
- MFCD01311056
- MOL File:
- 556-27-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (+)-L-Alliin analytical standard | 72805 | 10mg | $333 |
| (+)-Alliin ≥98% | 14002 | 1mg | $42 |
| (+)-Alliin ≥98% | 14002 | 5mg | $183 |
| (+)-Alliin ≥98% | 14002 | 10mg | $321 |
| (+)-Alliin ≥98% | 14002 | 1mg | $38 |
| More product size | |||
| Melting point | 164-166° (effervescence) |
|---|---|
| alpha | D20 +63.5° (c = 2) |
| Boiling point | 416.1±45.0 °C(Predicted) |
| Density | 1.205 (estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | solid |
| pka | 1.88±0.10(Predicted) |
| color | White to off-white |
| Merck | 13,259 |
| Major Application | food and beverages |
| InChI | InChI=1/C6H11NO3S/c1-2-3-11(10)4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-,11-/s3 |
| InChIKey | XUHLIQGRKRUKPH-DYEAUMGKSA-N |
| SMILES | C(O)(=O)[C@H](C[S@](CC=C)=O)N |&1:3,5,r| |
| LogP | -0.478 (est) |
| CAS DataBase Reference | 556-27-4(CAS DataBase Reference) |
| FDA UNII | 7I4L2D0E9G |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-10 | |||||||||
| HS Code | 29309090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Alliin price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 72805 | (+)-L-Alliin analytical standard | 556-27-4 | 10mg | $333 | 2026-04-30 | Buy |
| Cayman Chemical | 14002 | (+)-Alliin ≥98% | 556-27-4 | 1mg | $42 | 2026-04-30 | Buy |
| Cayman Chemical | 14002 | (+)-Alliin ≥98% | 556-27-4 | 5mg | $183 | 2026-04-30 | Buy |
| Cayman Chemical | 14002 | (+)-Alliin ≥98% | 556-27-4 | 10mg | $321 | 2026-04-30 | Buy |
| Cayman Chemical | 14002 | (+)-Alliin ≥98% | 556-27-4 | 1mg | $38 | 2024-03-01 | Buy |
Alliin Chemical Properties,Uses,Production
Description
Alliin (S-allyl cysteine sulfoxide) is an organic sulfur-containing product derived from the amino acid cysteine. It is the precursor of thiosulfinates, which are responsible for the characteristic pungent flavours of Allium species. It is an L-alanine derivative in which one of the methyl hydrogens of L-alanine has been replaced by an (S)-allyl sulfinyl group. It has a role as a plant metabolite, an antioxidant, a cardioprotective agent, a neuroprotective agent and an antimicrobial agent. It is a non-proteinogenic alpha-amino acid, an L-cysteine derivative, an L-alanine derivative, a sulfoxide and an olefinic compound. It is a tautomer of an alliin zwitterion.
Chemical Properties
Colorless block crystals, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from garlic.
Occurrence
Alliin is a sulfoxide that is a natural constituent of fresh garlic. It is a derivative of the amino acid cysteine. When fresh garlic is chopped or crushed, the enzyme alliinase converts alliin into allicin, which is responsible for the aroma of fresh garlic. Garlic powder is not a source of alliin, nor is fresh garlic upon maceration since the enzymatic conversion to allicin takes place in the order of seconds. Alliin was the first natural product with both carbon- and sulfur-centered stereochemistry[1].
Uses
antibacterial, antioxidant
Definition
ChEBI: An L-alanine derivative in which one of the methyl hydrogens of L-alanine has been replaced by an (S)-allylsulfinyl group.
benefits
Different from allicin, which is quickly metabolized into diallyl disulfide and allyl mercaptan, alliin with bioavailability of 16.5% has nearly no first liver pass effect except that some are converted to diallyl disulfide. An extensive literature review discloses the nutraceutical and medicinal potential of alliin in several aspects. For example, alliin decreased fasting glucose levels and increased insulin levels to the same extent as glibenclamide, glyclazide or insulin in diabetic rats. Weeks’ administration of alliin modified the redox environment by decreasing reactive substances in organs and increasing the catalase and superoxide dismutase activities in nicotine-fed rats. Another study showed that alliin markedly depressed the increase of plasma and liver cholesterol levels in rats fed a hypercholesterolemic diet containing 10% hydrogenated coconut oil, 1% cholesterol and 0.2% cholic acid. Alliin was also found to possess anti-inflammatory activities for bowel diseases. These symptoms like diabetes, high radicals, hypercholesterolemia and inflammation are all associated with obesity and/or metabolic diseases. Supportively, a meta-analysis suggests that the single component intake of garlic may be effective for lowering plasma glucose concentration and body weight[1].
Synthesis
21593-77-1
556-27-4
General procedure for the synthesis of (R)-3-((S)-allyl sulfinyl)-2-aminopropionic acid from (R)-3-(allyl sulfinyl)-2-aminopropionic acid: Pure 2-PeCS (0.2 mol) obtained in step (2) was dissolved in 250 mL of distilled water, and 0.28 mol of a 30% hydrogen peroxide solution was added slowly with magnetic stirring, and the stirring was continued for 12 hours. After completion of the reaction, insoluble impurities in the solution were removed by filtration, followed by the addition of 2 L of anhydrous ethanol, and the mixture was allowed to stand at 4 °C for 6 h to induce the formation of 2-PeCSO crystals. The crystals were collected by filtration and dried at 40 °C to obtain 33.6 g of thioallyl cysteine sulfoxide (2-PeCSO). The 2-PeCSO crystals made in step (3) were dissolved in 150 mL of distilled water, heated to 50 °C and a pre-diluted acetone solution (consisting of 96 mL of distilled water with 492 mL of acetone) was slowly added at this temperature and subsequently cooled to room temperature. The mixture was allowed to stand at 4°C for 12 hours. Next, another diluted acetone solution (a mixture of 8.2 mL of distilled water with 112 mL of acetone) was added at 50°C, heat-filtered and cooled to room temperature. The solution was again allowed to stand at 4°C for 12 hours to promote crystallization. Finally, the solution was purified by thermal filtration, the crystals were collected and dried in 15 mL of distilled water to give about 3.3 g of (+)2-PeCSO in pure form.
target
PPAR | TNF-α | IL Receptor | NF-kB | SOD | NADPH-oxidase | ROS
References
[1] Baiqiang Zhai. “Hypoglycemic and hypolipidemic effect of S-allyl-cysteine sulfoxide (alliin) in DIO mice.” Scientific Reports (2018): 3527.
Alliin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 3015 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Hovane Phytochemicals Co., Ltd | +86-17340288373 | victor.liu@hovane.com | China | 33 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 477 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
View Lastest Price from Alliin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-20 | Alliin
556-27-4
|
US $44.00-165.00 / mg | 99.39% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | (S)-3-(Allylsulphinyl)-L-alanine
556-27-4
|
US $0.00 / KG | 1KG | 99% | 100 tons | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2026-01-30 | Alliin, Garlic Extract
556-27-4
|
US $0.00-0.00 / kg | 1kg | 2.2% - 30% | 1 ton | Hovane Phytochemicals Co., Ltd |
-
- Alliin
556-27-4
- US $44.00-165.00 / mg
- 99.39%
- TargetMol Chemicals Inc.
-
- (S)-3-(Allylsulphinyl)-L-alanine
556-27-4
- US $0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Alliin, Garlic Extract
556-27-4
- US $0.00-0.00 / kg
- 2.2% - 30%
- Hovane Phytochemicals Co., Ltd
