DIPHENOXYLATE HYDROCHLORIDE
- CAS No.
- 3810-80-8
- Chemical Name:
- DIPHENOXYLATE HYDROCHLORIDE
- Synonyms
- DIPHENOXYLATE HCL;r1132;DIPHENOXYLATE HYDROCHLORIDE;Diphenoxylate hydrochloride solution;Diphenoxylate for system suitability;Diphenoxylate Hydrochloride CII (200 mg);Diphenoxylate HCL (Subj To Narcotic Permit);DIPHENOXYLATE HYDROCHLORIDE METHANOL SOL UTION;DIPHENOXYLATE HYDROCHLORIDE ANTIPERISTAL TIC, ANTI;Diphenoxylate Hydrochloride (1.0 mg/ml in Methanol)
- CBNumber:
- CB6305387
- Molecular Formula:
- C30H33ClN2O2
- Molecular Weight:
- 489.05
- MDL Number:
- MFCD00058213
- MOL File:
- 3810-80-8.mol
| Melting point | 220.5-222° |
|---|---|
| storage temp. | -20°C |
| solubility | Very slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent). |
| form | Solid |
| color | White to Off-White |
| FDA UNII | W24OD7YW48 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H310+H330-H317-H334 |
| Precautionary statements | P262-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310 |
| RIDADR | 1544 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2933330000 |
DIPHENOXYLATE HYDROCHLORIDE price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1219008 | Diphenoxylate for system suitability | 3810-80-8 | 200mg | $581 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | CHM0152896 | DIPHENOXYLATE HYDROCHLORIDE 95.00% | 3810-80-8 | 5MG | $774.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0152896 | DIPHENOXYLATE HYDROCHLORIDE 95.00% | 3810-80-8 | 50MG | $1871.1 | 2021-12-16 | Buy |
| Chemtos | D-2506 | DiphenoxylateHCl | 3810-80-8 | 10mg | $1200 | 2021-12-16 | Buy |
DIPHENOXYLATE HYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Originator
Lomotil,Searle,US,1960
Uses
Antiperistaltic; antidiarrheal. Controlled substance (opiate).
Definition
ChEBI: The hydrochloride salt of diphenoxylate.
Manufacturing Process
A mixture of 23 parts of the ethyl ester of 4-phenylisonipecotic acid and 15
parts of 2,2-diphenyl-4-
omobutyronitrile in 19 parts of xylene is heated for
24 hours at 100-120°C and then cooled and filtered to remove the precipitate
of the hydro
omide of the ethyl ester of 4-phenylisonipecotic acid. The
filtrate is then extracted with dilute hydrochloric acid and the extract is
rendered alkaline by addition of concentrated aqueous potassium hydroxide
and extracted with ether. This ether extract is treated with gaseous hydrogen
chloride. The resulting precipitate is collected on a filter. The hydrochloride of
the ethyl ester of 2,2-diphenyl-4-(4'-carboxy-4'-phenyl-1'-
piperidino)butyronitrile thus obtained melts at about 220.5-222°C. See
meperidine hydrochloride for synthesis of 4-phenyl-isonipecotic acid ethyl
ester.
Therapeutic Function
Antidiarrheal
Veterinary Drugs and Treatments
Diphenoxylate is an opiate in combination with atropine in antidiarrheal products used primarily in dogs; it also has antitussive properties. Use in cats is controversial and many clinicians do not recommend its use in this species.
DIPHENOXYLATE HYDROCHLORIDE Preparation Products And Raw materials
DIPHENOXYLATE HYDROCHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Zhuhai Anzhe Biotechnology Co,Ltd. | 13570603050 | 793448631@qq.com | China | 3015 | 58 |
| Changzhou Xianglong Pharmaceutical Technology Co., LTD | 18661161657 | yaoxiangqiu2021@163.com | China | 10066 | 58 |
| Henan Yingtian Biotechnology Co. LTD | 18339993703 | 570581550@qq.com | China | 719 | 58 |
| guoyungurui | 18162595016 | 3287908757@qq.com | China | 10015 | 58 |
| Pushan Industry (Shaanxi) Co., Ltd | 029-81310890 18165209495 | 2929288192@qq.com | China | 2462 | 58 |
View Lastest Price from DIPHENOXYLATE HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-23 | :DIPHENOXYLATE HYDROCHLORIDE
3810-80-8
|
US $1.00 / KG | 1KG | 97%-99.9% | 100kg | Career Henan Chemical Co |
-
- :DIPHENOXYLATE HYDROCHLORIDE
3810-80-8
- US $1.00 / KG
- 97%-99.9%
- Career Henan Chemical Co
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