"Desloratadine Citrate Disodium"
- CAS No.
- Chemical Name:
- "Desloratadine Citrate Disodium"
- Synonyms
- CBNumber:
- CB63060757
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Melting point | 150-151°C |
---|---|
storage temp. | -20°C Freezer |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
form | Solid |
color | White to Beige |
ATC code | R06AX27 |
"Desloratadine Citrate Disodium" Chemical Properties,Uses,Production
Uses
Desloratadine (Loratadine EP Impurity D; Loratadine USP Related Compound A) is an active metabolite of Loratadine (L469575) and used as an oral non-sedating antihistamine to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria (1,2,3).
Clinical Use
Antihistamine:
Symptomatic relief of allergy such as hay fever,
urticaria
Drug interactions
Potentially hazardous interactions with other drugs
Antivirals: concentration possibly increased by
ritonavir.
Metabolism
Desloratadine is the primary active metabolite of loratadine. Approximately 40% of the dose is excreted in the urine and 42% in the faeces over a 10 day period and mainly in the form of conjugated metabolites. Approximately 27% of the dose is eliminated in the urine during the first 24 hours. Less than 1% of the active substance is excreted unchanged in the active form, as desloratadine.
"Desloratadine Citrate Disodium" Preparation Products And Raw materials
Raw materials
Preparation Products
"Desloratadine Citrate Disodium" Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hefei Enruite Pharmaceutical Co., Ltd. | 0551-65318475 | 115795874@qq.com | China | 4 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 13675144456 | sean.lv@synzest.com | China | 10787 | 58 |
Shaanxi Dideu Medichem Co. Ltd | 029-81124267 15229202216 | 1073@dideu.com | China | 10010 | 58 |
Supplier | Advantage |
---|---|
Hefei Enruite Pharmaceutical Co., Ltd. | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 58 |
Shaanxi Dideu Medichem Co. Ltd | 58 |