ChemicalBook >> CAS DataBase List >>(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one

CAS No.
1700622-07-6
Chemical Name:
(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
Synonyms
Ezetimibe-9;Ezetimibe Impuriry I;(3R,4S)-1-(4-fluorophenyl);3?-(4-Methylphenyl)ezetimibe;4”DeFluoro-4”methyl-Ezetimibe;4-Desfluoro-4-methyl Ezetimibe;(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one;2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-hydroxy-3-(4-methylphenyl)propyl]-4-(4-hydroxyphenyl)-, (3R,4S)-;(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one? (Ezetimibe Impurity);Ezetimibe impuriry 11/ 4”DeFluoro-4”methyl-Ezetimibe/(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
CBNumber:
CB63128952
Molecular Formula:
C25H24FNO3
Molecular Weight:
405.46
MDL Number:
MFCD28358893
MOL File:
1700622-07-6.mol
Last updated:2023-04-23 13:52:06

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Properties

Melting point 161-164°C
Boiling point 663.6±55.0 °C(Predicted)
Density 1.271±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 9.72±0.30(Predicted)
color Off-White to Pale Beige
Stability Hygroscopic

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D228860 4”DeFluoro-4”methyl-Ezetimibe 1700622-07-6 5mg $180 2021-12-16 Buy
Product number Packaging Price Buy
D228860 5mg $180 Buy

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Chemical Properties,Uses,Production

Uses

4”DeFluoro-4”methyl-ezetimibe is a derivative of Ezetimibe (E975000), which is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Suppliers

Global( 42)Suppliers
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Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
BOC Sciences
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Hangzhou Huarong Pharm Co., Ltd.
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Aceschem Inc.
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China National Standard Pharmaceutical Corporation Limited
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Shanghai Payne Pharmaceutical Technology Co.Ltd
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Beijing Comparison Pharmaceutical Technology Co., Ltd 010-52878169 15701683040 sales@bjcomparison.com China 4673 58
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Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15185 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one 4-Desfluoro-4-methyl Ezetimibe 3?-(4-Methylphenyl)ezetimibe 2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-hydroxy-3-(4-methylphenyl)propyl]-4-(4-hydroxyphenyl)-, (3R,4S)- 4”DeFluoro-4”methyl-Ezetimibe Ezetimibe-9 (3R,4S)-1-(4-fluorophenyl) Ezetimibe impuriry 11/ 4”DeFluoro-4”methyl-Ezetimibe/(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe Impuriry I (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one? (Ezetimibe Impurity) 1700622-07-6