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1-Hydroxy-2-naphthoic acid

CAS No.
86-48-6
Chemical Name:
1-Hydroxy-2-naphthoic acid
Synonyms
NSC 3717;Xinafoic acid.;RARECHEM AL BE 0359;2-Carboxy-1-naphthol;1-Hydroxy-2-naphthoi;LABOTEST-BB LT00452757;1-Hydroxy-2-phthoic acid;hydroxy-2-naphthoic acid;1-Hydroxy-2-naphthoicaci;1-hydroxy-β-naphthoic acid
CBNumber:
CB6317591
Molecular Formula:
C11H8O3
Molecular Weight:
188.18
MDL Number:
MFCD00003960
MOL File:
86-48-6.mol
MSDS File:
SDS
Last updated:2023-11-01 14:00:35

1-Hydroxy-2-naphthoic acid Properties

Melting point 195-200 °C (dec.) (lit.)
Boiling point 283.17°C (rough estimate)
Density 1.2100 (rough estimate)
refractive index 1.6310 (estimate)
Flash point 150 °C
storage temp. Sealed in dry,Room Temperature
solubility alcohol: freely soluble
form Powder or Crystals
pka 3.02±0.30(Predicted)
color White to slightly pink to tan
Water Solubility SOLUBLE IN HOT WATER
Merck 14,4834
BRN 974438
InChIKey SJJCQDRGABAVBB-UHFFFAOYSA-N
LogP 3.196 (est)
CAS DataBase Reference 86-48-6(CAS DataBase Reference)
FDA UNII U8LZ3R07L8
EPA Substance Registry System 1-Hydroxy-2-naphthoic acid (86-48-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39-37
WGK Germany  3
TSCA  Yes
HS Code  29182910
NFPA 704
0
2 0

1-Hydroxy-2-naphthoic acid price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 109630 1-Hydroxy-2-naphthoic acid ≥97.0% 86-48-6 5g $34.1 2024-03-01 Buy
Sigma-Aldrich 109630 1-Hydroxy-2-naphthoic acid ≥97.0% 86-48-6 100g $59.5 2024-03-01 Buy
TCI Chemical H0279 1-Hydroxy-2-naphthoic Acid >98.0%(HPLC)(T) 86-48-6 25g $32 2024-03-01 Buy
TCI Chemical H0279 1-Hydroxy-2-naphthoic Acid >98.0%(HPLC)(T) 86-48-6 500g $322 2024-03-01 Buy
TCI Chemical H0279 1-Hydroxy-2-naphthoic Acid >98.0%(HPLC)(T) 86-48-6 100g $97 2024-03-01 Buy
Product number Packaging Price Buy
109630 5g $34.1 Buy
109630 100g $59.5 Buy
H0279 25g $32 Buy
H0279 500g $322 Buy
H0279 100g $97 Buy

1-Hydroxy-2-naphthoic acid Chemical Properties,Uses,Production

Chemical Properties

beige to brown-grey powder. 1-Hydroxy-2-naphthoic acid [86-48-6], C11H8O3, Mr 188.17, mp 200℃, is only sparingly soluble in hot water but readily soluble in alkali and ethanol. It couples with diazo compounds in the 4-position and, with excess, in the 4,7-positions. It is sulfonated by oleum to give the 4-sulfonic and then the 4,7-disulfonic acids. Halogenation occurs in the 4-position, and nitrosation gives 2-nitroso-1-naphthol.

Uses

Metabolite from phenanthrene degradation. 1-Hydroxy-2-naphthoic acid is used as an intermediate for azo and triphenylmethane dyes and, more recently, for color-film dyes.

Uses

It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Definition

ChEBI: 1-hydroxy-2-naphthoic acid is a naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms. It has a role as a bacterial xenobiotic metabolite and a fungal xenobiotic metabolite. It is a naphthoic acid, a member of naphthols and a hydroxy monocarboxylic acid. It is functionally related to a 2-naphthoic acid. It is a conjugate acid of a 1-hydroxy-2-naphthoate.

Preparation

Treatment of the dried sodium salt of 1-naphthol with carbon dioxide at 135℃ under pressure gives an 80 % yield of product.

General Description

1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones.

Purification Methods

Successively crystallise the acid from EtOH/water, diethyl ether and acetonitrile, with filtration through a column of charcoal and Celite. [Tong & Glesmann J Am Chem Soc 79 583 1957, Beilstein 10 H 331, 10 IV 1194.]

90-15-3
86-48-6
Synthesis of 1-Hydroxy-2-naphthoic acid from 1-Naphthol
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View Lastest Price from 1-Hydroxy-2-naphthoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Hydroxy-2-naphthoic acid pictures 2023-10-14 1-Hydroxy-2-naphthoic acid
86-48-6
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
1-Hydroxy-2-naphthoic acid pictures 2023-09-06 1-Hydroxy-2-naphthoic acid
86-48-6
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
1-Hydroxy-2-naphthoic acid pictures 2023-08-04 1-Hydroxy-2-naphthoic acid
86-48-6
US $20.00 / kg 1kg 99.99% 50000tons Henan Bao Enluo International TradeCo.,LTD
LABOTEST-BB LT00452757 RARECHEM AL BE 0359 Salmeterol Hydroxynaphthoic Acid Impurity (USP) ALPHA-HYDROXYNAPHTHOIC ACID 1-NAPHTHOL-2-CARBOXYLIC ACID 1-HYDROXY-2-NAPHTHOIC ACID 1-HYDROXY-NAPHTHALENE-2-CARBONIC ACID 1-Hydroxy-2-phthoic acid 1-Hydroxy-naphthalene-2-carboxylic acid for synthesis 1-hydroxy-β-naphthoic acid 2-Naphthalenecarboxylic acid, 1-hydroxy- 1-HYDROXYNAPHTHALENE-2-CARBOXYLIC ACID (1-HYDROXY-2-NAPHTHOIC ACID) 1-Hydroxy-2-naphthoic acid, 98+% 2-Carboxy-1-naphthol Hydroxynaphthalene-2-carboxylic acid Naphthol-2-carboxylic acid 1-Hydroxy-2-naphthoic acid,99% 1-Hydroxynaphthalene-2-carboxylic acid, 2-Carboxy-1-hydroxynaphthalene 1-Hydroxy-2-naphthoic acid, 99% 100GR 1-Hydroxy-2-naphthoic acid, 99% 5GR NSC 3717 Xinafoic acid. 1-Hydroxy-2-naphthoic acid >=97.0% 1-hydroxy-2-naphthalenecarboxylicaci 1-hydroxy-2-Naphthalenecarboxylicacid hydroxy-2-naphthoic acid Salmeterol Hydroxynaphthoic Acid Impurity 1-Hydroxy-2-naphthoic acid, 97%, for synthesis 1-Hydroxy-2-naphthoicAcid> 1-Hydroxy-2-naphthoicaci 1-Hydroxy-2-naphthoic acid ISO 9001:2015 REACH 1-Hydroxy-2-naphthoi 86-48-6 84-48-6 HOC10H6COOH C11H7O3 Organic Building Blocks Building Blocks Carboxylic Acids Carbonyl Compounds C11 to C12 CARBOXYLIC ACID Aromatics Intermediates of Dyes and Pigments bc0001