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FHPI HCL

CAS No.
350228-36-3
Chemical Name:
FHPI HCL
Synonyms
FHPI HCL;SB202190 HCL;SB 202190, HYDROCHLORIDE;SB 202190 monohydrochloride hydrate;SB 202190, Hydrochloride - CAS 350228-36-3 - Calbiochem;4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HCL;4-(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1h-imidazol-2-yl)phenol hydrochloride;4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-iMidazol-2-yl]phenol Monohydrochloride;4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HYDROCHLORIDE;4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol monohydrochloride hydrate
CBNumber:
CB6321057
Molecular Formula:
C20H15ClFN3O
Molecular Weight:
367.8
MDL Number:
MFCD01862621
MOL File:
Mol file
MSDS File:
SDS
Last updated:2023-06-08 09:02:49

FHPI HCL Properties

storage temp. -20°C
solubility DMSO: ≥12mg/mL
form solid
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37
WGK Germany  3
NFPA 704
0
2 0

FHPI HCL price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S7076 SB 202190 monohydrochloride hydrate ≥98% (HPLC) 350228-36-3 5mg $134 2024-03-01 Buy
Cayman Chemical 21201 SB 202190 (hydrochloride) ≥98% 350228-36-3 1mg $32 2024-03-01 Buy
Cayman Chemical 21201 SB 202190 (hydrochloride) ≥98% 350228-36-3 5mg $86 2024-03-01 Buy
Sigma-Aldrich S7076 SB 202190 monohydrochloride hydrate ≥98% (HPLC) 350228-36-3 25mg $545 2024-03-01 Buy
Cayman Chemical 21201 SB 202190 (hydrochloride) ≥98% 350228-36-3 10mg $122 2024-03-01 Buy
Product number Packaging Price Buy
S7076 5mg $134 Buy
21201 1mg $32 Buy
21201 5mg $86 Buy
S7076 25mg $545 Buy
21201 10mg $122 Buy

FHPI HCL Chemical Properties,Uses,Production

Uses

The water soluble form of SB 202190, a highly selective, potent inhibitor of p38 MAP kinase. SB-202190 is able to promote proliferation of C6 cells in lower concentration but induced apoptosis in higher levels. Studies show that SB202190 can protect neural function from ischemia/reperfusion injury and regulate the activation of Bcl-2 and Bax protein after ischemia/reperfusion in rat.

Uses

The water soluble form of SB 202190, a highly selective, potent inhibitor of p38 MAP kinase. SB-202190 is able to promote proliferation of C6 cells in lower concentration but induced apoptosis in high er levels. Studies show that SB202190 can protect neural function from ischemia/reperfusion injury and regulate the activation of Bcl-2 and Bax protein after ischemia/reperfusion in rat.

General Description

A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190 (Cat. No. 559388).

Biochem/physiol Actions

SB 202190 monohydrochloride hydrate mediates the phosphorylation of serine in the mutant p53 protein and modulates cell adhesion and prevents cell proliferation in breast cancer cell lines.

FHPI HCL Preparation Products And Raw materials

Raw materials

Preparation Products

FHPI HCL Suppliers

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94838 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 China 1494 55
SYN|thesis med chem P/L +86-021-50720296 service@synkinase.com China 266 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
SPIRO PHARMA eric_feng1954@126.com China 9254 55
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2317 55
SB202190 HCL SB 202190, HYDROCHLORIDE FHPI HCL 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-iMidazol-2-yl]phenol Monohydrochloride 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole monohydrochloride hydrate 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol monohydrochloride hydrate SB 202190 monohydrochloride hydrate 4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HCL 4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HYDROCHLORIDE SB 202190, Hydrochloride - CAS 350228-36-3 - Calbiochem 4-(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1h-imidazol-2-yl)phenol hydrochloride 350228-36-3 C20H15ClFN3O C20H14FN3OClH