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SS5020

SS5020 structure

CAS No.: 1334310-70-1

Chemical Name:: SS5020

Synonyms: SS5020;2-Propenoic acid, 3-[4-[(7-hydroxy-2-oxo-3-phenyl-2H-1-benzopyran-4-yl)methyl]phenyl]-, (2E)-

CBNumber:: CB63345566

Molecular Formula:: C25H18O5

Molecular Weight:: 398.41

MDL Number:: MFCD30481307

MOL File:: 1334310-70-1.mol

Last updated:2023-03-31 09:12:58

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SS5020 Properties

Boiling point	679.5±55.0 °C(Predicted)
Density	1.375±0.06 g/cm3(Predicted)
pka	4.50±0.10(Predicted)

SS5020 Chemical Properties,Uses,Production

Description

SS5020 is a a new benzopyran antiestrogen. Unlike tamoxifen (TAM), SS5020 exhibits no genotoxic activity to damage DNA. Furthermore, SS5020 does not present significant uterotrophic potential in rats; in contrast, the structurally related compounds, TAM, toremifene, raloxifene (RAL) and SP500263 all have uterotrophic activity. At the human equivalent molar dose of TAM (0.33 or 1.0 mg/kg), SS5020 had much stronger antitumor potential than those same antiestrogens against 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in rats.

SS5020 Preparation Products And Raw materials

Raw materials

Preparation Products

SS5020 2-Propenoic acid, 3-[4-[(7-hydroxy-2-oxo-3-phenyl-2H-1-benzopyran-4-yl)methyl]phenyl]-, (2E)- 1334310-70-1