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Sitagliptin Impurity 10

Sitagliptin Impurity 10 structure

CAS No.: 1253056-01-7

Chemical Name:: Sitagliptin Impurity 10

Synonyms: Sitagliptin-8;3-Hydroxy Sitagliptin;Sitagliptin Impurity 09;Sitagliptin phosphate impurity 6;Sitagliptin Hydroxy Amide Impurity;1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluo;1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone;1-Butanone, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-;3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;(R/S)-3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one

CBNumber:: CB63360062

Molecular Formula:: C16H14F6N4O2

Molecular Weight:: 408.3

MDL Number:: MFCD30747641

MOL File:: 1253056-01-7.mol

Last updated:2023-05-15 10:44:02

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Sitagliptin Impurity 10 Properties

Boiling point	542.2±60.0 °C(Predicted)
Density	1.61±0.1 g/cm3(Predicted)
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	13.69±0.20(Predicted)
color	White to Off-White

Sitagliptin Impurity 10 Chemical Properties,Uses,Production

Uses

1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin Impurity 10 Preparation Products And Raw materials

Raw materials

Preparation Products

Sitagliptin Impurity 10 Suppliers

Global( 40)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3149	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	021-58123769 18678586262	info@paynepharm.com	China	1354	58
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	6818	65
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-52878169 15701683040	sales@bjcomparison.com	China	4662	58
ChemStrong Scientific Co.,Ltd	0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632	sales@reading-chemicals.com	China	15185	58

Supplier	Advantage
Standardpharm Co. Ltd.	58
Hangzhou Huarong Pharm Co., Ltd.	58
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	58
Daicel Chiral Technologies (China)CO.,LTD	65
BOC Sciences	65
Beijing Comparison Pharmaceutical Technology Co., Ltd	58
ChemStrong Scientific Co.,Ltd	56
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58

1253056-01-7(Sitagliptin Impurity 10)Related Search:

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1of4

Sitagliptin-8 Sitagliptin Hydroxy Amide Impurity Sitagliptin impurity 41/Sitagliptin Hydroxy Amide Impurity/3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one 3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one 1-Butanone, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)- (R/S)-3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluo Sitagliptin phosphate impurity 6 Sitagliptin Impurity 09 3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one? (Sitagliptin Impurity） 3-Hydroxy Sitagliptin 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone 1253056-01-7