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4-Trifluoromethylphenol

Preparation method Chemical Characteristics Uses
4-Trifluoromethylphenol
4-Trifluoromethylphenol structure
CAS No.
402-45-9
Chemical Name:
4-Trifluoromethylphenol
Synonyms
TFMPO;TRIFLUORO-PARA-CRESOL;Fluoxetine Impurity 4;4-HYDROXYBENZOTRIFLUORI;4-trifluorotoluolphenol;p-TrifluoroMethylphenyl;α,α,α-Trifluoro-p-cresol;4-HYDROXYBENZOTRIFLUORIDE;4-(TRIFLUOROMETHYL)PHENOL;P-(TRIFLUOROMETHYL)PHENOL
CBNumber:
CB6371577
Molecular Formula:
C7H5F3O
Formula Weight:
162.11
MOL File:
402-45-9.mol

4-Trifluoromethylphenol Properties

Melting point:
45-47 °C(lit.)
Boiling point:
71.5-72 °C (8 mmHg)
Density 
1.3226 (estimate)
Flash point:
183 °F
storage temp. 
0-6°C
form 
Crystals
pka
pK1:8.675 (25°C)
color 
White to yellow-brown
BRN 
1637019
CAS DataBase Reference
402-45-9(CAS DataBase Reference)
NIST Chemistry Reference
p-Hydroxybenzotrifluoride(402-45-9)
EPA Substance Registry System
Phenol, 4-(trifluoromethyl)-(402-45-9)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,Xi
Risk Statements  22-37/38-41-36/37/38
Safety Statements  26-39-24/25
RIDADR  UN 2926 4.1/PG 2
WGK Germany  3
Hazard Note  Irritant/Keep Cold
PackingGroup 
HS Code  29081000
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H228 Flammable solid Flammable solids Category 1
Category 2
Danger
Warning
P210, P240,P241, P280, P370+P378
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4-Trifluoromethylphenol price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 178470 4-(Trifluoromethyl)phenol 97% 402-45-9 1g $26.1 2018-11-13 Buy
Sigma-Aldrich 178470 4-(Trifluoromethyl)phenol 97% 402-45-9 5g $81.2 2018-11-13 Buy
TCI Chemical H0644 4-Hydroxybenzotrifluoride >98.0%(GC)(T) 402-45-9 5g $93 2018-11-22 Buy
TCI Chemical H0644 4-Hydroxybenzotrifluoride >98.0%(GC)(T) 402-45-9 25g $278 2018-11-22 Buy
Sigma-Aldrich 178470 4-(Trifluoromethyl)phenol 97% 402-45-9 25g $293 2018-11-13 Buy

4-Trifluoromethylphenol Chemical Properties,Uses,Production

Preparation method

Chlorosilane and bromotrifluoromethane at-59℃form trifluoromethylsilane. Trifluoromethylsilane and benzoquinone in the presence of catalyst form 4-triethylsiloxy-4-trifluoromethyl-2,5-cyclohexadien-1-ketone which is reduced by zinc powder to p-trifluoromethylphenol with a yield of 71%. This method avoids the use of  hydrofluoric acid in the traditional process but  should be carried out under anhydrous conditions.If there were water trifluoromethyl silane would rapidly become silanol under the effect of water and alkali. The catalyst used in the reaction is alkali of which the strength has nothing to do with the catalytic activity. By now the role of catalyst is still unknown but the reaction can not proceed without catalyst.

Chemical Characteristics

Off-white crystal

Uses

For intermediate of medicine and pesticide.

Chemical Properties

White to yellowish-brown crystals

Uses

Intermediates of Liquid Crystals

4-Trifluoromethylphenol Preparation Products And Raw materials

Raw materials

Preparation Products


4-Trifluoromethylphenol Suppliers

Global( 305)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Fluoropharm Co., Ltd.
+8613336034509
sales@fluoropharm.com CHINA 735 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24192 60
Anhui Royal Chemical Co., Ltd.
+86-025-86736275
dana.jiang@royal-chem.com CHINA 488 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 27142 58
Qingdao Hongjin Trading Co., Ltd.
0532-83657313
hjt@hong-jin.com CHINA 220 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23967 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6370 58
Standardpharm Co. Ltd.
0714-3992388
yxzy@std-med.net CHINA 13064 58

View Lastest Price from 4-Trifluoromethylphenol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-02 4-Trifluoromethylphenol
402-45-9
US $100.00 / KG 1KG 99% Customized career henan chemical co

4-Trifluoromethylphenol Spectrum


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