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(-)-BICUCULLINE METHOCHLORIDE

(-)-BICUCULLINE METHOCHLORIDE Structure
(-)-BICUCULLINE METHOCHLORIDE structure
CAS No.
53552-05-9
Chemical Name:
(-)-BICUCULLINE METHOCHLORIDE
Synonyms
l-Bicuculline methochloride;(-)-BICUCULLINE METHOCHLORIDE;(?)-Bicuculline methochloride;(-)-Bicuculline methylchloride;( ) Bicuculline methochloride,()Bicuculline methochloride;[R-(R,S)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride;[R-(R*,S*)]-5-(6,8-DIHYDRO-8-OXOFURO[3,4-E]-1,3-BENZODIOXOL-6-YL)-5,6,7,8-TETRAHYDRO-6,6-DIMETHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLINIUM CHLORIDE;1,3-Dioxolo[4,5-g]isoquinolinium,5-[(6S)-6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-,chloride (1:1), (5R)-
CBNumber:
CB6373056
Molecular Formula:
C21H20ClNO6
Molecular Weight:
417.84
MDL Number:
MFCD00078981
MOL File:
53552-05-9.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:59
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(-)-BICUCULLINE METHOCHLORIDE Properties

storage temp. Store at RT
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form Powder
Water Solubility Soluble to 100 mM in water
FDA UNII I3UNE1K4AF

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS09,GHS06
Signal word  Danger
Hazard statements  H300-H400-H331-H311
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501-P273-P391-P501
NFPA 704
0
4 0

(-)-BICUCULLINE METHOCHLORIDE price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27802 (−)-Bicuculline methochloride 53552-05-9 10mg $115 2024-03-01 Buy
Cayman Chemical 27802 (−)-Bicuculline methochloride 53552-05-9 50mg $410 2024-03-01 Buy
Cayman Chemical 27802 (−)-Bicuculline methochloride 53552-05-9 5mg $64 2024-03-01 Buy
Cayman Chemical 27802 (−)-Bicuculline methochloride 53552-05-9 25mg $252 2024-03-01 Buy
TRC B382510 (-)-BicucullineMethochloride 53552-05-9 5mg $225 2021-12-16 Buy
Product number Packaging Price Buy
27802 10mg $115 Buy
27802 50mg $410 Buy
27802 5mg $64 Buy
27802 25mg $252 Buy
B382510 5mg $225 Buy

(-)-BICUCULLINE METHOCHLORIDE Chemical Properties,Uses,Production

Uses

(-)-Bicuculline Methochloride is a GABA receptor inhibitor. Convulsant.

Biological Activity

Methochloride salt of (+)-bicuculline ([R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one ). Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.

target

GABA Receptor

(-)-BICUCULLINE METHOCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-BICUCULLINE METHOCHLORIDE Suppliers

Global( 59)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Ascent Scientific 4401179829988 customerservice@ascentscientific.co.uk United Kingdom 279 60
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 7059 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 27322 60
Shanghai ChengShao Biological Technology Co., Ltd. 021-61847300 13341622919 shcss01@163.com China 4809 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 400-400-400-9004166 18616739031 3007523370@qq.com China 52712 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
InvivoChem 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Ascent Scientific 60
Wuhan ChemFaces Biochemical Co., Ltd. 55
EMMX Biotechnology LLC 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai ChengShao Biological Technology Co., Ltd. 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58

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[R-(R*,S*)]-5-(6,8-DIHYDRO-8-OXOFURO[3,4-E]-1,3-BENZODIOXOL-6-YL)-5,6,7,8-TETRAHYDRO-6,6-DIMETHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLINIUM CHLORIDE (-)-BICUCULLINE METHOCHLORIDE [R-(R,S)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride l-Bicuculline methochloride 1,3-Dioxolo[4,5-g]isoquinolinium,5-[(6S)-6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-,chloride (1:1), (5R)- (?)-Bicuculline methochloride ( ) Bicuculline methochloride,()Bicuculline methochloride (-)-Bicuculline methylchloride 53552-05-9 C21H20NO6Cl GABA/Glycine receptor GABA