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(S)-(-)-1,1'-Bi-2-naphthol

(S)-(-)-1,1'-Bi-2-naphthol structure

CAS No.: 18531-99-2

Chemical Name:: (S)-(-)-1,1'-Bi-2-naphthol

Synonyms: (S)-BINOL;(S)-1,1'-BI-2-NAPHTHOL;(S)-(-)-BINOL;(R,S)-BINOL;S-BINAPHTHOL;1,1'-BINAPHTHYL-2,2'-DIOL;(-)-Binol;AKOS 90560;98.0%(T&BI-2-NAPHTHOL

CBNumber:: CB6380427

Molecular Formula:: C20H14O2

Molecular Weight:: 286.32

MDL Number:: MFCD00004068

MOL File:: 18531-99-2.mol

MSDS File:: SDS

Last updated:2023-12-24 21:24:35

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(S)-(-)-1,1'-Bi-2-naphthol Properties

Melting point	215-218 °C
alpha	-35.5 º (c=1, THF)
Boiling point	388.69°C (rough estimate)
Density	1 g/cm³
refractive index	-36.0 ° (C=1, THF)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	dioxane: 50 mg/mL, clear
form	Crystals or Crystalline Powder
pka	8.29±0.50(Predicted)
color	White to light gray
optical activity	[α]22/D 34°, c = 1 in THF
Merck	14,1226
BRN	3592999
CAS DataBase Reference	18531-99-2(CAS DataBase Reference)
FDA UNII	54OT5RRV4C

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P302+P352-P305+P351+P338

Hazard Codes

T,Xi

Risk Statements

25-36-36/37/38

Safety Statements

26-45-24/25-36

RIDADR

UN 2811 6.1/PG 3

WGK Germany

RTECS

DU3106100

TSCA

HazardClass

6.1

PackingGroup

III

HS Code

29072990

NFPA 704

	1
2		0

(S)-(-)-1,1'-Bi-2-naphthol price More Price(49)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	246956	(S)-(?)-1,1′-Bi(2-naphthol) 99%	18531-99-2	1g	$47	2024-03-01	Buy
Sigma-Aldrich	246956	(S)-(?)-1,1′-Bi(2-naphthol) 99%	18531-99-2	5g	$58.8	2024-03-01	Buy
TCI Chemical	B1100	(S)-(-)-1,1'-Bi-2-naphthol >98.0%(HPLC)(T)	18531-99-2	5g	$97	2024-03-01	Buy
TCI Chemical	B1100	(S)-(-)-1,1'-Bi-2-naphthol >98.0%(HPLC)(T)	18531-99-2	25g	$292	2024-03-01	Buy
Alfa Aesar	L08423	(S)-(-)-1,1'-Bi(2-naphthol), 99%	18531-99-2	1g	$61.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
246956	1g	$47	Buy
246956	5g	$58.8	Buy
B1100	5g	$97	Buy
B1100	25g	$292	Buy
L08423	1g	$61.65	Buy

(S)-(-)-1,1'-Bi-2-naphthol Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

(S)-BINOL ligand in combination with titanium(IV) isopropoxide, forms (S)-(-)-BINOL-Ti complex, which is an effective chiral catalyst for:

asymmetric addition of alkynylzinc to unactivated ketones
enantioselective ring-opening reaction of meso-stilbene oxide and cyclohexene oxide with anilines
asymmetric aryl transfers from triaryl(tetrahydrofuran)aluminum reagents to a wide variety of ketones

It can also react with zirconium(IV) isopropoxide isopropanol complex to form a chiral Lewis acid catalyst for the facile enantioselective allylation of aldehydes by allyltributyltin.

Uses

Chiral ligand.

Definition

ChEBI: (S)-(-)-1,1'-Bi-2-naphthol is a member of naphthols.

Purification Methods

Dissolve it in cold 2.5N NaOH, extract with CH2Cl2, and acidify with 5% HCl. Collect the white precipitate and recrystallise it from aqueous EtOH and dry it in a vacuum [Akimoto & Yamada Tetrahedron 27 5999 1971]. It is optically stable in dioxane-water (100o/24hours). Racemisation: 72% in 1.2N HCl at 100o/24hours and 68% in 0.67M KOH in BuOH at 118o/23hours [Kyba et al. J Am Chem Soc 95 2693 1973]. It has also been crystallised from *C6H6 (solubility is 1%) using Norite or aqueous EtOH after chromatography through silica gel, eluting with Me2CO/*C6H6. [Kyba et al. J Org Chem 42 4173 1977; see also Brussee & Jansen Tetrahedron Lett 24 3261 1983, Akimoto & Yamada Tetrahedron 27 5999 1971, Beilstein 6 IV 7020.]

(S)-(-)-1,1'-Bi-2-naphthol Preparation Products And Raw materials

Raw materials

Copper(II) chloride dihydrate Ethanol Toluene Phosphorus oxychloride Triethylamine

(R)-(+)-1-Phenylethylamine L-1-Phenylethylamine Iron chloride hexahydrate Tetrahydrofuran Benzene

Ethyl acetate Dichloromethane 2-Naphthol

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Preparation Products

(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

(S)-(-)-1,1'-Bi-2-naphthol Suppliers

Global( 464)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	6710	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7845	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shanghai Arbor Chemical Co., Ltd.	021-60451682	act@arborchemical.com	CHINA	906	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2169	58

Supplier	Advantage
Shanghai UCHEM Inc.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Shanghai Arbor Chemical Co., Ltd.	58
Jinan Carbotang Biotech Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Changzhou Ditong Chemical Co.,Ltd	58

View Lastest Price from (S)-(-)-1,1'-Bi-2-naphthol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-02-23	(S)-(-)-1,1'-bi-2-naphthol 18531-99-2	US $12.00-193.00 / g	1g	0.98	25kg	Shanghai UCHEM Inc.
2023-12-24	5-BROMO-2-FLUOROPHENYLACETIC ACID 18531-99-2	US $100.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-01-31	(S)-(-)-1,1'-Bi-2-naphthol 18531-99-2	US $100.00 / kg	1kg	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd

(S)-(-)-1,1'-bi-2-naphthol
18531-99-2
US $12.00-193.00 / g
0.98
Shanghai UCHEM Inc.

5-BROMO-2-FLUOROPHENYLACETIC ACID
18531-99-2
US $100.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

(S)-(-)-1,1'-Bi-2-naphthol
18531-99-2
US $100.00 / kg
99%
Hebei Mojin Biotechnology Co., Ltd

(S)-(-)-1,1'-Bi-2-naphthol Spectrum

(S)-(-)-1,1'-Bi-2-naphthol(18531-99-2)FT-IR (S)-(-)-1,1'-Bi-2-naphthol(18531-99-2)IR (S)-(-)-1,1'-Bi-2-naphthol(18531-99-2)Raman

18531-99-2((S)-(-)-1,1'-Bi-2-naphthol)Related Search:

ALPHA-NAPHTHOLBENZEIN p-Naphtholbenzein Solvent Red 43 (n)-1,1'-bi(2-naphthol),(+/-)-1,1A-Bi-2-naphthol,(±)-1,1'-Bi(2-naphthol),99%,(+/-)-1,1'-BI(2-NAPHTHOL),1,1'-BI-2-NAPHTHOL 1-Naphthol

Terbinafine Hydrochloride 2-Naphthol Phenmedipham (S)-(-)-1,1''-BI-2-NAPHTHOL 99 E.E+% (R)-(+)-1,1'-Bi-2-naphthol

5,5',6,6',7,7',8,8'-Octahydro-bi-2-naphthol,(R)-(+)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol,99% (S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol (R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol (-1,1'-Bi-2-Naphthol Deacetate (S)-1,1μ-Binaphthalene-2,2μ-diyl bis(trifluoromethanesulfonate), (S)-1,1μ-Bi(2-naphthol) bis(trifluoromethanesulfonate)

(S)-(-)-3,3'-Dibromo-1,1'-bi-2-naphthol,(S)-(-)-3,3'-Dibromo-1,1'-bi-2-naphthol,99% (S)-(-)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol,99% (S)-6,6'-DIMETHYL-1,1'-BI-2-NAPHTHOL,6,6'-Dimethyl-1,1'-bi-2-naphthol

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AKOS 90560 S-(-)-1,1'-Bi-2-naphthol,99%(S)-BINOL 1,1-Binaphthalene-2,2-diol, (1S)- S-BINOL/S-(-)-1.1''-BINAPHTHYL-2.2''-DIOL (S)-(-)-1,1'-Bi-2-naphtol S-(-)-2,2''-DIHYDROXY-1,1''-DINAPHTHYL (S)-BINOL (S)-1,1 -BI-2-NAPHTHOL ***REVERSE*** S-1,1-Bi-2-Naphtho (S)-[1,1']-Binaphth-2-ol, (S)-BINOL (-)-2,2μ-Dihydroxy-1,1μ-dinaphthyl, (S)-(-)-1,1μ-Binaphthalene-2,2μ-diol, (S)-BINOL [aS,(-)]-1,1'-Binaphthalene-2,2'-diol [aS,(-)]-2,2'-Dihydroxy-1,1'-binaphthalene [aS,(-)]-Dinaphthol (1S)-1,1'-Binaphthalene-2,2'-diol, (S)-BINOL (S)-(-)-1,1'-Bi-2-naphthol,99% （S）-(-)-1_Bi-3-naphthol (S)-(-)-1,1'-Bi-2-na (1S)-2,2'-Dihydroxy-[1,1']-binaphthyl (R)-(+)-2,2'-DIHYDROXY-1,1'-BINAPHTHYL (s)-(-)-1,1’-bi-2-nanphthol 1,1'-BI-2,2'-NAPHTHOLS [1,1']BINAPHTHALENYL-2,2'-DIOL (+/-)-1,1'-BINAPHTHALENE-2,2'-DIOL (S)-(-)-BINOL (S)-(-)-2,2'-Dihydroxy-1,1'-binaphthyl (S)-(-)-1,1''-BINAPHTHYL-2,2''-DIOL FOR SY (S)-1,1'-Binaphthalene-2,2'-diol, (S)-BINOL (S)-(-)-1,1'-Bi-2-naphthol S-(-)-2,2'-Dihydroxy-1,1'-binaphthyl AURORA KA-7212 BI-2-NAPHTHOL DI-B-NAPHTHOL (-)-2,2'-DIHYDROXY-1,1'-DINAPHTHYL (+)-2,2'-DIHYDROXY-1,1'-DINAPHTHYL (+/-)-2,2'-DIHYDROXY-1,1'-DINAPHTHYL 2,2'-DIHYDROXY-1,1'-DINAPHTHYL 2,2'-DINAPHTHOL (S)-(-)-1,1'-Bi-2-naphthol (S)-(-)-1,1'-Bi-2-naphthol, >=99.5% (S)-(-)-1,1'-Bi-2-phthol (S)-(-)-1,1'-Binaphthyl-2,2'-diol for synthesis (R)-(+)-2,2'-DIHYDROXY-1,1-BINAPHTHYL (R)-(+)-1,1'-BI(2,2'-NAPHTHOL) (R)-(+)-1,1'-BINAPHTHYL-2,2'-DIOL R(+)-1,1'-BINAPHTHALENE-2,2'-DIOL (R)-[1,1]-BINAPHTHALENYL-2,2'-DIOL (R)-(+)-1,1'-BIS(2-NAPHTHOL) S-(-)-2,2'-DIHYDROXY-1,1'-DINAPHTHYL (S)-(-)-2,2'-DIHYDROXY-1,1'-BINAPHTHYL (S)-(-)-2,2'-DIHYDROXY-1,1-BINAPHTHYL (S)-[1,1]-BINAPHTHALENYL-2,2'-DIOL (S)-(-)-1,1'-BINAPHTHYL-2,2'-DIOL (S)-[1,1'-BINAPHTHALENE]-2,2'-DIOL S(-)-1,1'-BINAPHTHALENE-2,2'-DIOL (S)-(-)-1,1'-BI(2,2'-NAPHTHOL) (S)-(-)-1,1'-BI-2-NAPHTHOL (S)-(+)-1,1'-BI-2-NAPHTHOL (S)-1,1-BI-2-NAPHTHOL 98.0%(T& (1S)-[1,1'-Binaphthalene]-2,2'-diol