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(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE

CAS No.
74588-78-6
Chemical Name:
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
Synonyms
D-6413;CS-888;D-64131;D 64131; D64131;D-64131(sc-203908);(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE;Methanone,(5-methoxy-1H-indol-2-yl)phenyl-;tubulin-inhibitory,D64131,Inhibitor,D-64131,G2/M,antiproliferative,inhibit,Microtubule/Tubulin,phase,carcinoma,antimitotic,activity,cytotoxicity,D 64131,astrocytoma
CBNumber:
CB6390031
Molecular Formula:
C16H13NO2
Molecular Weight:
251.28
MDL Number:
MFCD04039791
MOL File:
74588-78-6.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:13

(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE Properties

Melting point 162 °C
Boiling point 455.2±25.0 °C(Predicted)
Density 1.231±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Soluble in DMSO
form Crystalline solid
pka 14.81±0.30(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J65995 D-64131 74588-78-6 10mg $154 2021-12-16 Buy
Cayman Chemical 22944 D-64131 ≥98% 74588-78-6 5mg $97 2024-03-01 Buy
Cayman Chemical 22944 D-64131 ≥98% 74588-78-6 10mg $175 2024-03-01 Buy
Cayman Chemical 22944 D-64131 ≥98% 74588-78-6 25mg $385 2024-03-01 Buy
Cayman Chemical 22944 D-64131 ≥98% 74588-78-6 50mg $577 2024-03-01 Buy
Product number Packaging Price Buy
J65995 10mg $154 Buy
22944 5mg $97 Buy
22944 10mg $175 Buy
22944 25mg $385 Buy
22944 50mg $577 Buy

(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE Chemical Properties,Uses,Production

Uses

Novel inhibitor of tubulin polymerization

Definition

ChEBI: (5-methoxy-1H-indol-2-yl)-phenylmethanone is a N-acylindole.

Biological Activity

Novel inhibitor of tubulin polymerization; cytotoxic and inhibits tumor cell proliferation in vitro (IC 50 = 74 nM). Prevents growth of tumor models in mice following oral administration in vivo .

References

1. beckers t, reissmann t, schmidt m et al. 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors. cancer res. 2002 jun 1;62(11):3113-9.

(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 72)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69

View Lastest Price from (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE pictures 2021-01-06 (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
74588-78-6
US $1.00 / g 1g 85.0-99.8% 20tons Career Henan Chemica Co
D-64131 (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE D-6413 D-64131(sc-203908) CS-888 D 64131; D64131 Methanone,(5-methoxy-1H-indol-2-yl)phenyl- tubulin-inhibitory,D64131,Inhibitor,D-64131,G2/M,antiproliferative,inhibit,Microtubule/Tubulin,phase,carcinoma,antimitotic,activity,cytotoxicity,D 64131,astrocytoma 74588-78-6 Inhibitors Caspases/Apoptosis