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13(R)-HODE

CAS No.
10219-69-9
Chemical Name:
13(R)-HODE
Synonyms
13(R)-HODE;Coriolic acid;13(R) HODE,13(R)HODE;HNICUWMFWZBIFP-PIHGWCCBSA-N;13(R)-hydroxy-9,11-octadienoic acid;13R-HYDROXY-9Z,11E-OCTADECADIENOIC ACID;(R-(E,Z))-13-Hydroxy-9,11-octadecadienoic acid;(R,9Z,11E)-13-Hydroxy-9,11-octadecadienoic acid;9,11-Octadecadienoic acid, 13-hydroxy-, (R-(E,Z))-;9,11-Octadecadienoic acid, 13-hydroxy-, (9Z,11E,13R)-
CBNumber:
CB6395450
Molecular Formula:
C18H32O3
Molecular Weight:
296.44
MDL Number:
MFCD00084834
MOL File:
10219-69-9.mol
Last updated:2023-07-14 17:48:47

13(R)-HODE Properties

Boiling point 422.7±20.0 °C(Predicted)
Density 0.970±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka 4.78±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

13(R)-HODE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 38605 13(R)-HODE ≥98% 10219-69-9 25μg $81 2024-03-01 Buy
Cayman Chemical 38605 13(R)-HODE ≥98% 10219-69-9 50μg $137 2024-03-01 Buy
Cayman Chemical 38605 13(R)-HODE ≥98% 10219-69-9 100μg $238 2024-03-01 Buy
Cayman Chemical 38605 13(R)-HODE ≥98% 10219-69-9 250μg $553 2024-03-01 Buy
American Custom Chemicals Corporation CCH0004495 13R-HYDROXY-9Z,11E-OCTADECADIENOIC ACID 95.00% 10219-69-9 5MG $502.62 2021-12-16 Buy
Product number Packaging Price Buy
38605 25μg $81 Buy
38605 50μg $137 Buy
38605 100μg $238 Buy
38605 250μg $553 Buy
CCH0004495 5MG $502.62 Buy

13(R)-HODE Chemical Properties,Uses,Production

Description

13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.1 13(R)-HODE is a weak (IC50 = 2.7 μM) inhibitor of U-46619-induced platelet aggregation.2

Definition

ChEBI: 13(R)-HODE is a 13-HODE in which the stereocentre at position 13 has S-configuration. It is a conjugate acid of a 13(R)-HODE(1-).

References

1. Baer, A.N., Costello, P.B., and Green, F.A. Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells Biochim. Biophys. Acta 1085(1),45-52(1991).
2. Lagarde, M., Boutillon, M.M., Guichardant, M., et al. Further studies on the anti-thromboxane A2 activity of monohydroxylated fatty acids Biochem. Pharmacol. 38,1863-1864(1989).

13(R)-HODE Preparation Products And Raw materials

Raw materials

Preparation Products

13(R)-HODE Suppliers

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13(R)-HODE 13R-HYDROXY-9Z,11E-OCTADECADIENOIC ACID (R,9Z,11E)-13-Hydroxy-9,11-octadecadienoic acid Coriolic acid (R-(E,Z))-13-Hydroxy-9,11-octadecadienoic acid 9,11-Octadecadienoic acid, 13-hydroxy-, (R-(E,Z))- 13(R)-hydroxy-9,11-octadienoic acid HNICUWMFWZBIFP-PIHGWCCBSA-N 9,11-Octadecadienoic acid, 13-hydroxy-, (9Z,11E,13R)- 13(R) HODE,13(R)HODE 10219-69-9