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ROTENONE

ROTENONE
ROTENONE structure
CAS No.
83-79-4
Chemical Name:
ROTENONE
Synonyms
CUBE;nekoe;Nusyn;canex;Cubor;Deril;ent133;Extrax;gerane;Haiari
CBNumber:
CB6397762
Molecular Formula:
C23H22O6
Formula Weight:
394.41718
MOL File:
83-79-4.mol

ROTENONE Properties

Melting point:
159-164 °C(lit.)
Boiling point:
210-220 °C0.5 mm Hg(lit.)
alpha 
-115 º (C=1.4 IN CHLOROFORM)
Density 
1.1917 (rough estimate)
refractive index 
1.4593 (estimate)
storage temp. 
Store at RT
form 
White to off-white solid
Water Solubility 
15 mg l-1 (100 °C)
Merck 
14,8271
BRN 
6773081
Stability:
Stable, but light and air sensitive. Combustible. Incompatible with oxidizing agents, especially in the presence of alkalies.
NIST Chemistry Reference
Rotenone(83-79-4)
EPA Substance Registry System
[1]Benzopyrano[3, 4-b]furo[2,3-h][1]benzopyran- 6(6aH)-one, 1,2,12,12a-tetrahydro-8,9- dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)-(83-79-4)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H315-H319-H335-H410
Precautionary statements  P261-P273-P301+P310-P305+P351+P338-P501-P280-P301+P310+P330-P337+P313-P391
Hazard Codes  T,N
Risk Statements  25-36/37/38-50/53
Safety Statements  22-24/25-36-45-60-61
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  DJ2800000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29329990
Toxicity LD50 i.p. in mice: 2.8 mg/kg (Fukami); in rats (mg/kg): 132 orally; 6 i.v. (Soloway)

ROTENONE price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 45656 Rotenone PESTANAL , analytical standard 83-79-4 250mg $20.3 2018-11-13 Buy
Sigma-Aldrich 557368 Rotenone 83-79-4 1gm $86 2018-11-20 Buy
Cayman Chemical 13995 Rotenone ≥95% 83-79-4 5g $98 2018-11-13 Buy
Cayman Chemical 13995 Rotenone ≥95% 83-79-4 1g $49 2018-11-13 Buy
Sigma-Aldrich R8875 Rotenone ≥95% 83-79-4 1g $83.4 2018-11-13 Buy

ROTENONE Chemical Properties,Uses,Production

Chemical Properties

white or off-white powder

Chemical Properties

Rotenone is a colorless to red odorless crystal- line solid; a white crystalline solid when pure; oxidation will cause yellowing to bright red coloring. Odorless.

Uses

Rotenone is used for the control of aphids, thrips, suckers and other insects in fruit and vegetable cultivation. It is also used for control in buildings, for the control of lice, ticks and warble fly on animals and as a piscicide for the management of fish populations.

Uses

acaricide, ectoparasiticide, antineoplastic, mitochondrial poison

Uses

Rotenone is an broad spectrum insecticide that occurs naturally in seeds and stems of several plants.

Uses

Pesticide.

Definition

ChEBI: A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy group (the 2R,6aS,12aS-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of Derris elliptica).

General Description

Colorless to brownish crystals or a white to brownish-white crystalline powder. Has neither odor nor taste.

Air & Water Reactions

ROTENONE decomposes upon exposure to light or air. Insoluble in water.

Reactivity Profile

ROTENONE is readily oxidized in the presence of alkalis. ROTENONE is incompatible with oxidizers. .

Hazard

Toxic by ingestion, overexposure can be fatal, irritant to skin, eyes and upper respiratory tract. Central nervous system impairment. Ques- tionable carcinogen.

Fire Hazard

Flash point data for ROTENONE are not available; however, ROTENONE is probably combustible.

Agricultural Uses

Insecticide, Acaracide, Veterinary medicine: The use of rotenone as a pesticide to kill invasive fish species is currently the only allowable use of this pesticide. Rotenone is a selective, nonspecific botanical insecticide with some acaricidal properties, and has been used in agriculture to control insects on vine fruit, flowers and vegetables. Registered for use in the U.S.A U.S. EPA restricted Use Pesticide (RUP) due to acute inhalation, acute oral, and aquatic toxicity. Agricultural and residential uses and all food uses were voluntarily cancelled in 2006[83]. In 2006, registrants requested voluntarily cancellation of all livestock, residential and home owner uses, domestic pet uses, and all other uses except for pesticide uses. In 2011 the use of this pesticide chemical was linked to Parkinson’s disease. Not listed for use in EU countries.

Trade name

ACME® Rotenone; AROL GORDON DUST®; BARBASCO®; BONIDE CUKE AND MELON DUST®; CENOL GARDEN DUST®; CHEM FISH®; CHEM-MITE®; CUBE®; CUBE EXTRACT®; CUBEPULVER®; CUBEROL®; CUBE ROOT®; CUBOR®; CUREX FLEA DUSTER®; DACTINOL®; DERIL®; DERRIN®; DERRIS®; DRI-KIL®; ENT-133®; EXTRAX®; FISH-TOX®; GREEN CROSS WARBLE POWDER®; HAIARI®; LIQUID DERRIS®; MEXIDE®; NICOULINE®; NOXFIRE®; NOXFISH®; PARADERIL®; POWDER AND ROOT®; PRENTOX®; PRO-NOX FISH®; RO-KO®; RONONE®; ROTACIDE®; ROTEFIVE®; ROTEFOUR®; ROTESSENOL®; SINID®; TOX-R®; TUBATOXIN®

Biological Activity

Mitochondrial electron transport chain inhibitor (IC 50 = 1.7 - 2.2 μ M at complex I). Inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC 50 = 3.4 nM). Commonly used pesticide and induces Parkinsonism in animal models. Cell-permeable and brain penetrant.

Potential Exposure

A potential danger to those involved in extraction from derris root, formulation or application of this insecticide. Rotenone is used as a pharmaceutical and veterinary drug.

Metabolic pathway

By hepatic microsomal incubations from rainbow trout with 14C-rotenone, three major and several minor metabolites of rotenone are observed, the major ones being identified as rotenolone and two epimeric forms of 6' ,7' -dihydroxyrotenone.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2588 Pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Degradation

Rotenone is racemised in base to less insecticidal compounds and it is decomposed on exposure to light and air (PM). Photochemical degradation in methanol of seven rotenoids isolated from Tephrosa villosa (Krupadanam et al., 1978) resulted generally in much decomposition but rotenone was relatively stable under the conditions used. When the compound was used as an insecticidal spray it was converted by light and air into dehydro-rotenone (2) and rotenonone (3). These structures are shown in Scheme 1.

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explo- sions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, and alkalies.

Waste Disposal

Rotenone is decomposed by light and alkali to less insecticidal products. It is readily detoxified by the action of light and air. It is also detoxified by heating; 2 hours @ 100 ? C results in 76% decomposition. Oxidation products are probably nontoxic. Incineration has been recommended as a disposal procedure. Burial with lime would also present minimal danger to the environ- ment . In accordance with 40CFR165, follow recommen- dations for the disposal of pesticides and pesticide containers. Must be disposed properly by following pack- age label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

ROTENONE Preparation Products And Raw materials

Raw materials

Preparation Products


ROTENONE Suppliers

Global( 177)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24191 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2258 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 12231 58
Kono Chem Co., Ltd
+86-132 8924 6953(Whatsapp/Wechat)
+86-29-86107037 info@konochemical.com CHINA 2997 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35440 58

View Lastest Price from ROTENONE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-23 ROTENONE
83-79-4
US $250.00-230.00 / G 50G 95% Customized career henan chemical co

ROTENONE Spectrum


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