ANTI-GLUTAMATE DECARBOXYLASE, G65
- CAS No.
- Chemical Name:
- ANTI-GLUTAMATE DECARBOXYLASE, G65
- Synonyms
- Anti-GAD2;ANTI-GAD 65;Anti-MGC161605;Anti-MGC161607;ANTI-GAD 65, 5-22;ANTI-GAD 65, 514-530;Anti-Glutamate decarboxylase 2;ANTI-GLUTAMATE DECARBOXYLASE, 65;ANTI-GLUTAMATE DECARBOXYLASE, G65;ANTI-GLUTAMIC ACID DECARBOXYLASE 65
- CBNumber:
- CB6406646
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03455043
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319 |
Precautionary statements | P305+P351+P338 |
WGK Germany | 3 |
ANTI-GLUTAMATE DECARBOXYLASE, G65 price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SAB2500444 | Anti-GAD2/GAD65 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 100μG | $568 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA044637 | Anti-GAD2 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy | |
Sigma-Aldrich | G5038 | Anti-Glutamic Acid Decarboxylase 65 (5-22) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 0.2mL | $333.2 | 2024-03-01 | Buy | |
Sigma-Aldrich | G4913 | Anti-Glutamic Acid Decarboxylase 65 (514-530) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 0.2mL | $313.2 | 2024-03-01 | Buy | |
Sigma-Aldrich | G1166 | Monoclonal Anti-Glutamic Acid Decarboxylase 65 antibody produced in mouse clone GAD-6, purified immunoglobulin, buffered aqueous solution | 100μg | $817 | 2024-03-01 | Buy |
ANTI-GLUTAMATE DECARBOXYLASE, G65 Chemical Properties,Uses,Production
Uses
Anti-Glutamic Acid Decarboxylase 65 antibody produced in rabbit is suitable as a primary antibody for the determination of expression of GAD 65 isoform in putative P boutons in rat and mouse at a working dilution of 1:5000 and in lysates prepared from rat testis at different developmental ages and rat cerebellum by immunoblotting.
It is also suitable for immunohistochemistry at a working dilution of 1:500 using formalin-fixed, paraffin-embedded sections of rat pancreas and for microarray.
General Description
GAD is predominantly expressed in the central nervous system (CNS) and pancreatic islets. It is also expressed in testis, oviduct and ovary. GAD exists in two isofoms, GAD 65 and GAD 67. GAD65 is targeted to membranes and nerve endings.
Biochem/physiol Actions
Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L-glutamate to γ-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. It has been identified as an autoantigen in insulin-dependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS) and may serve as a marker in the early stages of IDDM. GAD 65 synthesizes transmitter GABA for vesicular release.
ANTI-GLUTAMATE DECARBOXYLASE, G65 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-GLUTAMATE DECARBOXYLASE, G65 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |