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4-Fluoroacetophenone

CAS No.
403-42-9
Chemical Name:
4-Fluoroacetophenone
Synonyms
1-(4-Fluorophenyl)ethan-1-one;1-(4-FLUOROPHENYL)ETHANONE;4-Fluoracetophenon;P-FLUOROACETOPHENONE;4'-FLUOROACETOPHENONE;p-Fluoro;AKOS BBS-00003234;Fluoroacetophenone3;4-FLUOROCETOPHENONE;4-FLUOROACETOPHENONE
CBNumber:
CB6419110
Molecular Formula:
C8H7FO
Molecular Weight:
138.14
MDL Number:
MFCD00000354
MOL File:
403-42-9.mol
MSDS File:
SDS
Modify Date:2022-12-21 16:56:50

4-Fluoroacetophenone Properties

Melting point 4 °C
Boiling point 77-78 °C10 mm Hg(lit.)
Density 1.143 g/mL at 20 °C(lit.)
refractive index n20/D 1.511(lit.)
Flash point 160 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Ethyl Acetate
form Liquid
Specific Gravity 1.138
color Clear colorless to slightly yellow
BRN 386013
InChIKey ZDPAWHACYDRYIW-UHFFFAOYSA-N
CAS DataBase Reference 403-42-9(CAS DataBase Reference)
FDA UNII TVQ090602V
NIST Chemistry Reference Ethanone, 1-(4-fluorophenyl)-(403-42-9)
EPA Substance Registry System 4'-Fluoroacetophenone (403-42-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-23
WGK Germany  3
TSCA  T
HazardClass  IRRITANT
HS Code  29147090
NFPA 704
2
2 0

4-Fluoroacetophenone price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F3207 4′-Fluoroacetophenone 99% 403-42-9 25g $52.3 2023-01-07 Buy
Sigma-Aldrich F3207 4′-Fluoroacetophenone 99% 403-42-9 100g $90.9 2023-01-07 Buy
TCI Chemical F0261 4'-Fluoroacetophenone >98.0%(GC) 403-42-9 25g $19 2023-01-07 Buy
TCI Chemical F0261 4'-Fluoroacetophenone >98.0%(GC) 403-42-9 500g $167 2023-01-07 Buy
Alfa Aesar A13950 4'-Fluoroacetophenone, 99% 403-42-9 100g $72.2 2021-12-16 Buy
Product number Packaging Price Buy
F3207 25g $52.3 Buy
F3207 100g $90.9 Buy
F0261 25g $19 Buy
F0261 500g $167 Buy
A13950 100g $72.2 Buy

4-Fluoroacetophenone Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

4’-Fluoroacetophenone is an intermediate used for the synthetic preparation of various pharmaceutical good and agricultural products.

Uses

4’Fluoroacetophenone is an intermediate used for the synthetic preparation of various pharmaceutical good and agricultural products.

Uses

4-Fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis


General procedure: Oximes (1.0 mmol), Amberlyst-15 (0.02 g), FPA53-NO2(0.02 g), and solvent (1.5 mL) were introduced into a 25-cm-high, 90-mL autoclave with a glass tube inside equipped with magnetic stirrer (Scheme 2). Then the autoclave was charged with oxygen to 0.1 MPa. The reaction mixture was stirred at desirable temperature for special time. Progress of the reaction was monitored by thin-layer chromatography (TLC) or gas chromatography (GC). After the reaction, the resin (Amberlyst-15 and FPA53-NO2) was separated from the reaction mixture by filtration and extracted with 3 mL CH3CN (2 1.5 ml). The solvent was removed under reduced pressure. The residue was further purified by column chromatography on silica gel (300 mesh) with hexane/ethyl acetate to give the corresponding carbonyl compounds.

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View Lastest Price from 4-Fluoroacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Fluoroacetophenone pictures 2023-01-30 4-Fluoroacetophenone
403-42-9
US $3.00 / kg 1kg 99.5% 500mt Jinan Finer Chemical Co., Ltd
4-Fluoroacetophenone pictures 2023-01-30 4-Fluoroacetophenone
403-42-9
US $100.00 / KG 1KG 99% 10 ton Hanhong Medicine Technology (Hubei) Co., Ltd.
4'-Fluoroacetophenone pictures 2023-01-30 4'-Fluoroacetophenone
403-42-9
US $0.00-0.00 / kg 1kg 99% 100000kgs per Month Shanghai Qyubiotech Co., Ltd.
Acetophenone, 4'-fluoro- para-Fluoroacetophenone 4-FLUOROCETOPHENONE 4-FLUOROACETOPHENONE AKOS BBS-00003234 Fluoroacetophenone color less liq Fluoroacetophenone3 4'-Fluoroacetophenone 1-(4-Fluorophenyl)ethan-1-one 1-(4-Fluorophenyl)ethanone 4-Fluoroacetophenone,99% LABOTEST-BB LT01148215 p-Fluoro 4'-Fluoroacetophenone 99% Ethanone, 1-(4-fluorophenyl)- 1-(4-fluorophenyl)-ethanon 1-Acetyl-4-fluorobenzene 4-Acetylphenyl fluoride Methyl 4-fluorophenyl ketone 4-Acetylfluorobenzene 4-Fluorophenyl Methyl ketone 4-Fluorophenylethanal Methyl 4-fluorophenyl Of Fluoroacetophenone 1-(4-Fluorophenyl)ethan-1-one, 1-(4-Fluorophenyl)-1-oxoethane The fluorine acetophenone p-Fluorophenyl methyl ketone 4'-Fluoroacetophenone> 4'-Fluoroacetophenone, 99%, for synthesis Haloperidol Decanoate EP Impurity L Haloperidol Decanoate Impurity 12(Haloperidol Decanoate EP Impurity L) Lidocaine Pharmaceutical Drugs Bromperidol decanoate EP Impurity L TIANFU-CHEM 4-Fluoroacetophenone 4-Fluoroacetophenone pure, 98% P-FLUOROACETOPHENONE 4'-FLUOROACETOPHENONE 1-(4-Fluorophenyl)ethan-1-one 1-(4-FLUOROPHENYL)ETHANONE 4-Fluoracetophenon Haloperidol EP Impurity L Haloperidol Decanoate Impurity L 403-42-9 C7 to C8 Carbonyl Compounds Building Blocks Organic Building Blocks Ketones Adehydes, Acetals & Ketones Fluorine Compounds C7 to C8 Carbonyl Compounds Ketones Acetophenone series Benzenes Aromatic Acetophenones & Derivatives (substituted) Organics ketone Fluorobenzene bc0001