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2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE

2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE
2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE structure
CAS No.
182004-65-5
Chemical Name:
2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE
Synonyms
IN1281;KB-R7943;KB-R7943 MESYLATE;KB-R7943 - CAS 182004-65-5 - Calbiochem;2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE;S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate;4-((4-Nitrobenzyl)oxy)phenethyl carbaMiMidothioate Methanesulfonate;S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate >2-(2-(4-(4-NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA, METHANE SULFONATE;S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate
CBNumber:
CB6422033
Molecular Formula:
C17H21N3O6S2
Formula Weight:
427.5
MOL File:
182004-65-5.mol

2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE Properties

storage temp. 
Inert atmosphere,2-8°C
form 
White crystalline solid

2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich K4144 KB-R7943 ≥98% (HPLC), powder 182004-65-5 5 mg $122 2021-12-16 Buy
Sigma-Aldrich 420336-M KB-R7943 - CAS 182004-65-5 - Calbiochem 182004-65-5 5mg-m $147 2021-12-16 Buy
Sigma-Aldrich 420336-M KB-R7943 - CAS 182004-65-5 - Calbiochem 182004-65-5 5 mg $147 2021-12-16 Buy
Sigma-Aldrich K4144 KB-R7943 ≥98% (HPLC), powder 182004-65-5 25 mg $487 2021-12-16 Buy
TCI Chemical N0966 S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate >98.0%(HPLC) 182004-65-5 10mg $137 2021-12-16 Buy

2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE Chemical Properties,Uses,Production

Uses

KB-R7943 Mesylate is a selective inhibitor of the reverse mode of Na+/Ca2+ exchange in cells expressing NCX1.

General Description

A cell-permeable inhibitor of the influx/reverse mode of the Na+/Ca2+ exchanger (NCX) (IC50 = 4.3 μM for NCX1, 4.7 μM for NCX2, and 1.4 μM for NCX3). Directly modulates Na+/Mg2+ exchange in a Ca2+-dependent manner. Reported ot offer neuronal and cardio-protection against ischemic injury. Also inhibits nicotinic acetylcholine receptors and NMDA receptor channels (IC50<10 μM).

Biological Activity

Potent, selective inhibitor of the reverse mode of the Na + /Ca 2+ exchanger (IC 50 = 0.7 mM). Does not affect Na + -dependent transport systems, Na + channels or ionotropic glutamate receptors.

Biochem/physiol Actions

Target IC50: 4.3 μM, 4.7 μM, and 1.4 μM for NCX1,NCX2, and NCX3, respectively

2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE Preparation Products And Raw materials

Raw materials

Preparation Products


2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE Suppliers

Global( 96)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hefei Hirisun Pharmatech Co., Ltd
86-15056975894
86-0551-62678551 shawn@hirisunpharm.com CHINA 9927 58
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26782 60
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
career henan chemical co
15093356674 0371-55982848
0086-371-86658258 factory@coreychem.com CHINA 29863 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19231 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
0551-65418697 sales@tnjchem.com CHINA 37441 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
13588875226 86-571-88216897、88216896
86-571-88216895 sales@hzclap.com CHINA 6469 58
Finetech Industry Limited
86 27 87465837
86 27 87772287 info@finetechnology-ind.com CHINA 9373 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132148 58
Hefei Hirisun Pharmatech Co., Ltd. 15056975894 0551-62678551
0551-62678551 sales@hirisunpharm.com China 654 55

View Lastest Price from 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-02-01 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE
182004-65-5
US $1.00 / KG 1KG 99% 200kgs Career Henan Chemical Co

182004-65-5(2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE)Related Search:


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  • 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE
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  • S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate >
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  • 182004-65-5
  • C16H17N3O3SCH3SO3H
  • C17H21N3O6S2
  • C16H17N3O3SCH4O3S
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  • Signalling
  • Ion transporter and other ion channel
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