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Ethyl diethoxyphosphinylformate

CAS No.
1474-78-8
Chemical Name:
Ethyl diethoxyphosphinylformate
Synonyms
Foscarnet EP Impurity D;Foscarnet impurity D CRS;TRIETHYL PHOSPHONOFORMATE;Triethyl carboxyphosphonate;Triethyl phosphonomethanoate;Foscarnet Related CoMpound D;Diethyl carbethoxyphosphonate;TRIETHYL PHOSPHONOFORMATE 98%;ethyl diethyl-phosphonoformate;Ethyl diethoxyphospinylformate
CBNumber:
CB6423762
Molecular Formula:
C7H15O5P
Molecular Weight:
210.16
MDL Number:
MFCD00009108
MOL File:
1474-78-8.mol
Last updated:2023-04-23 13:52:06

Ethyl diethoxyphosphinylformate Properties

Boiling point 135 °C12 mm Hg(lit.)
Density 1.11 g/mL at 25 °C(lit.)
refractive index n20/D 1.423(lit.)
Flash point >230 °F
storage temp. Store below +30°C.
solubility Chloroform (Slightly), Methanol (Slightly)
color Colorless to Almost colorless
Specific Gravity 1.11
BRN 1781949
Stability Moisture Sensitive
CAS DataBase Reference 1474-78-8(CAS DataBase Reference)
FDA UNII TUX6M928ID
NIST Chemistry Reference Phosphinecarboxylic acid, diethoxy-, ethyl ester, oxide(1474-78-8)
EPA Substance Registry System Phosphinecarboxylic acid, diethoxy-, ethyl ester, oxide (1474-78-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P280g-P302+P352a-P321-P333+P313-P501a
Hazard Codes  Xi
Risk Statements  36/37/38-43
Safety Statements  24/25-36/37-26-37-24
WGK Germany  3
TSCA  Yes
HS Code  2931 39 90
NFPA 704
1
1 0

Ethyl diethoxyphosphinylformate price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2870 Foscarnet Related Compound D pharmaceutical secondary standard, certified reference material 1474-78-8 0.5ML $634 2024-03-01 Buy
Sigma-Aldrich 1283324 Foscarnet Related Compound D United States Pharmacopeia (USP) Reference Standard 1474-78-8 0.27ml $1140 2024-03-01 Buy
TCI Chemical E0400 Ethyl Diethoxyphosphinylformate 1474-78-8 25g $40 2024-03-01 Buy
Alfa Aesar B23367 Ethyl diethoxyphosphinylformate, 97+% 1474-78-8 100g $46.4 2021-12-16 Buy
Alfa Aesar B23367 Ethyl diethoxyphosphinylformate, 97+% 1474-78-8 25g $16.7 2021-12-16 Buy
Product number Packaging Price Buy
PHR2870 0.5ML $634 Buy
1283324 0.27ml $1140 Buy
E0400 25g $40 Buy
B23367 100g $46.4 Buy
B23367 25g $16.7 Buy

Ethyl diethoxyphosphinylformate Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

Diethyl (Ethoxycarbonyl)phosphonate is an impurity in the synthesis of Foscarnet (F727400), an inhibitor of viral DNA polymerase and reverse transcriptase. Foscarnet is used as an antiviral.

General Description

for synthesis

Purification Methods

Dissolve it in Et2O, shake this with H2O (to remove any trace of NaCl impurity), dry (Na2SO4), evaporate and distil it using an efficient fractionating column. [Nylén Chem Ber 57 1035 1924, Reetz et al. J Am Chem Soc 77 3813 1955, Monson Advanced Organic Synthesis Academic Press p 89 1972, Beilstein 3 II 103.]

Ethyl diethoxyphosphinylformate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 149)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 7836 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Shaanxi Dideu Medichem Co. Ltd
18192627656 1012@dideu.com China 3911 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9641 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
AFINE CHEMICALS LIMITED
0571-85134551 info@afinechem.com CHINA 15377 58

View Lastest Price from Ethyl diethoxyphosphinylformate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Triethyl Phosphonoformate   pictures 2020-03-16 Triethyl Phosphonoformate
1474-78-8
US $1.00-0.00 / KG 1KG 99% 20 tons Shaanxi Dideu Medichem Co. Ltd
Ethyl diethoxyphosphinylformate pictures 2020-01-01 Ethyl diethoxyphosphinylformate
1474-78-8
US $1.00 / ASSAYS 1ASSAYS 99% 500kg Career Henan Chemical Co
Diethyl carbethoxyphosphonate Diethyl ethoxycarbonylphosphonate Ethyl diethoxyphosphinecarboxylate oxide Formic acid, phosphono-, triethyl ester phosphinecarboxylicacid,diethoxy-,ethylester,oxide Triethyl carboxyphosphonate Triethyl phosphonomethanoate (ETHOXYCARBONYL)PHOSPHONIC ACID DIETHYL ESTER ETHYL DIETHOXYPHOSPHINYLFORMATE DIETHOXYPHOSPHINYLFORMIC ACID ETHYL ESTER TRIETHYL PHOSPHONOFORMATE TRIETHYL PHOSPHONOFORMATE 98% PhosphonoformicacidTriethylester Ethyl diethoxyphosphinylformate,98% TRIETHYL PHOSPHONOFORMATE (ETHYL DIETHOXYPHOSPHINILFORMATE) ethyl diethyl-phosphonoformate ETHYL DIETHOXYPHOSPHINYLFORMATE (TRIETHYL PHOSPHONOFORMATE) Foscarnet Related Compound D (0.27 mL) (O,O-diethyl ethoxycarbonylphosphonate) Diethoxyphosphinylformic Acid Ethyl Ester (Ethoxycarbonyl)phosphonic Acid Diethyl Ester Triethyl Phosphonoformate Foscarnet Related CoMpound D Ethyl diethoxyphospinylformate Foscarnet Related Compound D (O,O-diethyl ethoxycarbonylphosphonate) (1283324) Foscarnet EP Impurity D Phosphinecarboxylic acid, 1,1-diethoxy-, ethyl ester, 1-oxide Foscarnet impurity D CRS Foscarnet Sodium Impurity 4(Foscarnet Sodium EP Impurity D) Foscarnet Sodium EP Impurity D Foscarnet USP Related Compound D Foscarnet Sodium Hexahydrate EP Impurity D Foscarnet Sodium EP Impurity D (Foscarnet USP Related Compound D) 1474-78-8 C2H5O2POCOOC2H5 C7H15O5P Building Blocks Phosphorus Compounds Phosphonates/Phosphinates Organic Building Blocks Organic Building Blocks Phosphonates/Phosphinates Phosphorus Compounds