ChemicalBook >> CAS DataBase List >>Piroctone olamine
Piroctone olamine
- CAS No.
- 68890-66-4
- Chemical Name:
- Piroctone olamine
- Synonyms
- OCTOPIROX;OCTO;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one;PIROCTONE OLEAMINE;LGB-PO;octopiroxolamine;PIROCTONE OLAMINE;Piorctone Olamine;PiroCLone olaMine;Pirotone Oleamine
- CBNumber:
- CB6433396
- Molecular Formula:
- C16H30N2O3
- Molecular Weight:
- 298.43
- MDL Number:
- MFCD01690792
- MOL File:
- 68890-66-4.mol
Last updated:2024-04-19 20:05:26
| Melting point | 134.0 to 138.0 °C |
|---|---|
| Boiling point | 135-235℃[at 101 325 Pa] |
| Density | 1.1[at 20℃] |
| vapor pressure | 0-0Pa at 20-25℃ |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly, Sonicated), Methanol (Slightly) |
| pka | 5.9-7.4[at 20 ℃] |
| color | White to Off-White |
| Water Solubility | 400-50000mg/L at 20-25℃ |
| Merck | 14,7502 |
| InChI | InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2 |
| InChIKey | BTSZTGGZJQFALU-UHFFFAOYSA-N |
| SMILES | C(N)CO.C(C1=CC(C)=CC(=O)N1O)C(C)CC(C)(C)C |
| LogP | 1.05-3.86 at 20-25℃ |
| CAS DataBase Reference | 68890-66-4(CAS DataBase Reference) |
| EWG's Food Scores | 1-2 |
| FDA UNII | A4V5C6R9FB |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318-H412 | |||||||||
| Precautionary statements | P273-P280-P302+P352-P305+P351+P338+P310 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UU7786150 | |||||||||
| HS Code | 2933399090 | |||||||||
| NFPA 704 |
|
Piroctone olamine price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 51872 | Piroctone olamine analytical standard | 68890-66-4 | 100mg | $142 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1544406 | Piroctone olamine United States Pharmacopeia (USP) Reference Standard | 68890-66-4 | 200mg | $436 | 2024-03-01 | Buy |
| TCI Chemical | P2178 | Piroctone Olamine >97.0%(HPLC)(T) | 68890-66-4 | 1g | $141 | 2024-03-01 | Buy |
| TCI Chemical | P2178 | Piroctone Olamine >97.0%(HPLC)(T) | 68890-66-4 | 5g | $471 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR2187 | Piroctone Olamine Pharmaceutical Secondary Standard; Certified Reference Material | 68890-66-4 | 500mg | $689 | 2024-03-01 | Buy |
Piroctone olamine Chemical Properties,Uses,Production
Description
Piroctone olamine (INN; also known as piroctone ethanolamine; brand name Octopirox) is a compound sometimes used in the treatment of fungal infections.Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone.
Appearance
White or slightly yellow crystalline powder.
Solubility
Freely soluble in 10% ethanol in water; soluble in solution containing surfactants in water or in 1%-10% ethanol; slightly soluble in water and in oil. The solubility in water varies by pH value, and is a litter larger in neutral or weak basic solution than in acid solution.
Toxicity
Acute toxicity : Acute oral LD50 –rat 8100mg/kg, practically nontoxic.
Subchronic toxicity : NOEL: 100mg//kg/d (rat, orally, 3 months).
Chronic toxicity and carcinogencity : Negative.
Mutagenicity : Negative.
Irritation to skin and eye : Very low.
Uses
Piroctone Olamine is an anti-dandruff agent used in shampoo formulations.
Uses
Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. Recently was shown, that piroctone olamine could induce apoptosis and possessed a significant in vivo effect against myeloma.
Definition
ChEBI: An organoammonium salt that is the ethanolamine salt of piroctone.
brand name
Octopirox (Hoechst AG, Germany).
Side effects
It should be kept in mind that shampoos with Piroctone Olamine should not be used more than twice a week, unlike other daily-use shampoos that don't have this ingredient. One of the biggest side effects of Piroctone Olamine is that it can cause irritation and itchiness on the head.
Synthesis of Piroctone olamine from Monoethanolamine and 4-Methyl-6-(2,4,4-trimethylpentyl)-2H-pyran-2-one
Piroctone olamine Preparation Products And Raw materials
Global( 486)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
| EAST STAR BIOTECH (SUZHOU) CO., LTD. | +8617706846989 | marketing@eaststarbio.com | China | 48 | 58 |
| Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd. | +86-18616643091 +86-18616643091 | info@rochipharma.com | China | 246 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19639 | 58 |
| BLiT (Hefei)Chemical Co.,Ltd | +86-551-62622640 | sales@blitchem.com | China | 291 | 58 |
| Wuhan Boyuan Import & Export Co., LTD | +8615175982296 | Mike@whby-chem.com | China | 974 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 | sales@ichemie.com | China | 985 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 | hbjbtech@163.com | China | 1000 | 58 |
| Shandong Juchuang Chemical Co., LTD | +86-18885615001 +86-18885615001 | admin@juchuangchem.com | China | 387 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@airuikechemical.com | China | 994 | 58 |
View Lastest Price from Piroctone olamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-19 | Piroctone olamine
68890-66-4
|
US $6.00 / KG | 1KG | More than 99% | 2000KG/MONTH | Hebei Saisier Technology Co., LTD | |
 |
2024-04-19 | Piroctone olamine
68890-66-4
|
US $0.00 / KG | 1KG | 99% | 1000 TONS | BLiT (Hefei)Chemical Co.,Ltd | |
 |
2024-04-19 | Piroctone olamine
68890-66-4
|
US $0.00 / Kg/Drum | 1KG | 99% | 200mt/year | Jinan Finer Chemical Co., Ltd |
-
- Piroctone olamine
68890-66-4
- US $6.00 / KG
- More than 99%
- Hebei Saisier Technology Co., LTD
-
- Piroctone olamine
68890-66-4
- US $0.00 / KG
- 99%
- BLiT (Hefei)Chemical Co.,Ltd
-
- Piroctone olamine
68890-66-4
- US $0.00 / Kg/Drum
- 99%
- Jinan Finer Chemical Co., Ltd
68890-66-4(Piroctone olamine)Related Search:
2(1H)-Pyridinone,1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-,compd.with2-aminoethanol(1:1)
4,4-trimethylpentyl)-1-hydroxy-4-methyl-6-(compd.with2-2(1h)-pyridinon
octopiroxolamine
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1h)-pyridinoncompd.with2-aminoethanol(1:1)
Hydroxyl pyrazole ketones
1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)
-one compound with 2-aminoethanol (1:1)
Ethanolamine salt (1:1)
1-hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine salt
PIROCTONE OLAMINE
Piroctone olamine (OCTO)
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
Piorctone Olamine
1-HYDROXY-4-METHYL-6-(2,4,4-TRIMETHYLPENTYL)2(1H)-PYRIDONE.
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-on, Verbindung mit 2-Aminoethanol (1:1)
1-hydroxy-4-Methyl-6-(2,4,4-triMethylpentyl)pyridin-2(1H)-one-2-aMinoethanol (1:1)
Pyridine-aMino ethanol
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone·2-aminoethanol
2-Aminoethanol/1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone,(1:1)
Piroctone Olamine (200 mg)
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanolammonium salt
PiroCLone olaMine
Piroctone olamine Solution, 100ppm
PIROCTONE OLAMINE 98.0+%
LGB-PO
4-methyl-1-oxido-6-(2,4,4-trimethylpentyl)-2-pyridinone
Piroctone olamine/octopirox
Piroctone Olamine >
Piroctone ethanolamine
2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compd.with 2-aminoethanol (1:1)OTHER CA INDEX NAMES:Ethanol, 2-amino-, compd. with1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone (1:1)
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone Ethanolamine
Sinobio Anti Dangdruff Piroctone Olamine Oct for Shampoo CAS?68890-66-4?Octopirox
Piroctone Olamine (1544406)
OCTOPIROX
PIROCTONE OLEAMINE
OCTO
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one
Jarguard OCT Piroctone Oleamine
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one 2-aminoethanol salt
Pirotone Oleamine
HYDROXYPYRIDINONE（OCT）
Piroctone olamine analytical standard, ≥99%
1-HYDROXY-4-METHYL6-(2,4,4-TRI METHYL
PHENYL)-2-PYRIDONE MONO ETHANOL
AMINE(PIROCTONE OLAMINE)
Piroctone Olamine (PO
1-hydroxy-4-methyl-6- (2,4,4-trimethylpentyl)pyridin-2-one (Piroctone olamine)
Piroctone ethanolamine salt
HYDROXYPYRIDINONE（OCT）/Piroctone olamine
68890-66-4
68890-64-4
951-78-4
C14H23NO2C2H7NOC16H30N2O3
C14H23NO2C2H7NO
C14H23NO2C2H7NOC16H30
bacteriostatic and fungistatic
ARAMINE
OLED materials,pharm chemical,electronic