Purine
- CAS No.
- 120-73-0
- Chemical Name:
- Purine
- Synonyms
- 9H-PURINE;1H-Purine;7H-Purine;X 128;PURINE;NSC 753;Isopurine;Purine 98%;Purine,99%;Purine,>98%
- CBNumber:
- CB6447322
- Molecular Formula:
- C5H4N4
- Molecular Weight:
- 120.11
- MDL Number:
- MFCD00079221
- MOL File:
- 120-73-0.mol
- MSDS File:
- SDS
| Melting point | 214-217 °C (lit.) |
|---|---|
| Boiling point | 214.09°C (rough estimate) |
| Density | 1.3106 (rough estimate) |
| refractive index | 1.7380 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Crystals |
| pka | 2.3(at 20℃) |
| color | White |
| Water Solubility | 400 g/L (20 ºC) |
| Merck | 7942 |
| BRN | 3200 |
| CAS DataBase Reference | 120-73-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NCI Dictionary of Cancer Terms | purine |
| FDA UNII | W60KTZ3IZY |
| NIST Chemistry Reference | 9H-Purine(120-73-0) |
| EPA Substance Registry System | Purine (120-73-0) |
| UNSPSC Code | 12352005 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| WGK Germany | 3 | |||||||||
| RTECS | UO7450000 | |||||||||
| HS Code | 29335995 | |||||||||
| Toxicity | LD50 intraperitoneal in rat: 800mg/kg | |||||||||
| NFPA 704 |
|
Purine price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P55805 | Purine 98% | 120-73-0 | 1g | $206 | 2024-03-01 | Buy |
| Alfa Aesar | J60999 | Purine, 98% | 120-73-0 | 1g | $227 | 2024-03-01 | Buy |
| TRC | P840288 | Purine | 120-73-0 | 50mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | C6588 | Purine | 120-73-0 | 100mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-W008627 | Purine >98.0% | 120-73-0 | 1g | $65 | 2021-12-16 | Buy |
Purine Chemical Properties,Uses,Production
Chemical Properties
very slightly yellow to cream crystalline powder
Uses
Purine can undergo direct C-H functionalization in the presence of palladium catalyst to form various biologically important products.
Uses
Organic synthesis, metabolism, and biochemi- cal research. (2) One of a number of basic compounds found in living matter and having a purine-type molecular structure.
Uses
Purine can be used human immunogenic epitopes of H,K, and E human endogenous retroviruses.
Definition
purine: An organic nitrogenous base(see formula), sparingly soluble inwater, that gives rise to a group ofbiologically important derivatives,notably adenine and guanine,which occur in nucleotides and nucleicacids (DNA and RNA).
Definition
A simple nitrogenous organic molecule with a double ring structure. Members of the purine group include adenine and guanine, which are constituents of the nucleic acids, and certain plant alkaloids, such as caffeine and theobromine.
Definition
ChEBI: The 9H-tautomer of purine.
Biosynthesis
Basically, the same pathway is found in all organisms capable of purine biosynthesis de novo. The initial substrate is the highly phosphorylated sugar 5-phosphoribosyl-α-1-pyrophosphate (PRPP). An amino group is transferred from glutamine to PRPP catalyzed by the enzyme glutamine PRPP amidotransferase. After that, it takes four reactions to complete the imidazole ring and an additional five reactions to synthesize the pyrimidine moiety and thereby to complete the purine molecule. In some bacteria (e.g., B. subtilis and Escherichia coli), the third step is also catalyzed by a second enzyme (purT) that uses formate instead of a tetrahydrofolic acid derivative as formyl donor. The sixth step has been found to be a two-step reaction, which in some organisms is catalyzed by a single enzyme. The end product of the de novo purine biosynthetic pathway is IMP. After the formation of IMP, purine synthesis splits into two separate pathways leading to the synthesis of AMP and GMP. The control point for feedback inhibition by purine nucleotides and activation by PRPP is on the activity of the first enzyme of the pathway glutamine PRPP amidotransferase. The branching from IMP is regulated by ATP and GTP to ensure a proper balance between ATP and GTP.
General Description
Purine is a heterocyclic organic compound constituting a pyrimidine ring fused to an imidazole ring.
Purification Methods
It crystallises from toluene or EtOH, and sublimes at 100-150o/0.1mm or 160o/10-4mm. The picrate has m 207-209o after crystallisation from 20volumes of H2O. [Beilstein 26 H 354, 26 III/IV 1736.]
Purine Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22787 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9641 | 58 |
