ChemicalBook >> CAS DataBase List >>4'-Demethylepipodophyllotoxin

4'-Demethylepipodophyllotoxin

CAS No.
6559-91-7
Chemical Name:
4'-Demethylepipodophyllotoxin
Synonyms
4'-DMEP;Etoposide impurity E;Podophyllotoxin Derivate 1;Demethylpodophyllotoxin, 4'-;4'-Demethylepipodophyllotoxi;4’-Dmethylepipodophyllotoxin;4-DEMETHYL EPIPODOPHYLLOTOXIN;4 -DEMETHYL EIPODOPHYLLOTOXIN;Podophyllotoxin EP Impurity B;4'-Demethylepipodophyllotoxin
CBNumber:
CB6447599
Molecular Formula:
C21H20O8
Molecular Weight:
400.38
MDL Number:
MFCD00189421
MOL File:
6559-91-7.mol
Last updated:2025-04-17 18:22:24

4'-Demethylepipodophyllotoxin Properties

Melting point 246-248°C
Boiling point 626.5±55.0 °C(Predicted)
Density 1.446±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 9.94±0.40(Predicted)
color White to Off-White
FDA UNII X0S6I23X6L
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H350-H360
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
HS Code  29349990
NFPA 704
0
1 0

4'-Demethylepipodophyllotoxin price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR3362 Teniposide Related Compound A certified reference material, pharmaceutical secondary standard 6559-91-7 20MG $404 2024-03-01 Buy
Sigma-Aldrich 1643747 Teniposide Related Compound A United States Pharmacopeia (USP) Reference Standard 6559-91-7 10MG $952 2022-05-15 Buy
TCI Chemical D5653 4'-Demethylepipodophyllotoxin 6559-91-7 1G $41 2024-03-01 Buy
TCI Chemical D5653 4'-Demethylepipodophyllotoxin 6559-91-7 5G $187 2024-03-01 Buy
Cayman Chemical 28393 4''-Demethylepipodophyllotoxin 6559-91-7 1g $68 2024-03-01 Buy
Product number Packaging Price Buy
PHR3362 20MG $404 Buy
1643747 10MG $952 Buy
D5653 1G $41 Buy
D5653 5G $187 Buy
28393 1g $68 Buy

4'-Demethylepipodophyllotoxin Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

A potent inhibitor of microtubule assembly.

Definition

ChEBI: An organic heterotetracyclic compound that is the 9- epimer of 4'-demethylpodophyllotoxin.

in vivo

4'-Demethylepipodophyllotoxin (1 μg/mL, 200 μL, topical application, 24 weeks) reduces the tumor incidence, tumor volume, and the conversion efficiency of papillomas to squamous cell carcinomas in DMBA/TPA-induced mouse skin carcinogenesis model[1].

518-28-5
6559-91-7
Synthesis of 4'-Demethylepipodophyllotoxin from Podophyllotoxin

4'-Demethylepipodophyllotoxin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 354)Suppliers
Supplier Tel Email Country ProdList Advantage
Anhuyan (Hainan) Biotechnology Co., LTD
+8618163349544 mollylucking@foxmail.com China 2764 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-+86-371-66670886 info@dakenam.com China 19777 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21629 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29860 58
Biochempartner
0086-13720134139 candy@biochempartner.com CHINA 965 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58

View Lastest Price from 4'-Demethylepipodophyllotoxin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4'-Demethylepipodophyllotoxin pictures 2025-03-03 4'-Demethylepipodophyllotoxin
6559-91-7
US $0.00 / kg 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4'-Demethylepipodophyllotoxin pictures 2025-02-14 4'-Demethylepipodophyllotoxin
6559-91-7
US $0.00 / G/KG 1G/KG 99% 1000000KG Anhuyan (Hainan) Biotechnology Co., LTD
4'-Demethylepipodophyllotoxin pictures 2024-11-19 4'-Demethylepipodophyllotoxin
6559-91-7
US $138.00 / mg 99.61% 10g TargetMol Chemicals Inc.

4'-Demethylepipodophyllotoxin Spectrum

(5R)-5,8,8aβ,9-Tetrahydro-9α-hydroxy-5β-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aαH)-one (5R)-5β-(3,5-Dimethoxy-4-hydroxyphenyl)-7α-(hydroxymethyl)-8α-hydroxy-5,6,7,8-tetrahydronaphtho[2,3-d]-1,3-dioxole-6β-carboxylic acid 6,7-lactone (5R)-5β-(3,5-Dimethoxy-4-hydroxyphenyl)-9α-hydroxy-5,5aα,6,8,8aβ,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6-one (5R,5aα,8aβ)-5,8,8a,9-Tetrahydro-5β-(4-hydroxy-3,5-dimethoxyphenyl)-9α-hydroxyfuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one 4-Domethylpodophyllotoxin, 4'-demethyl-epi-Podophyllotoxin 4'-O-deMethylepipodophyllotoxin 4-DeMethyl Epipodophyllotoxin(DMEP) Demethylpodophyllotoxin, 4'- Podophyllotoxin Derivate 1 oxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5r-(5-alpha,5a-beta,8a-alpha,9-beta)) 4'-DMEP 4'-DEMETHYLEPIPODOPHYLLOTOXINE 4-DEMETHYL EPIPODOPHYLLOTOXIN Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR,9S)- 4 -DEMETHYL EIPODOPHYLLOTOXIN 4 -DEMETHYL EIPODOPHYLLOTOXIN 95% (5R,5aR,8aR,9S)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one 4'-Demethylepipodophyllotoxin ,98% (5R,5aR,8aR,9S)-9-Hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one Etoposide impurity E Etoposide Impurity 5 (Etoposide EP Impurity E) Podophyllotoxin p-Desmethyl 9-Epimer 4'-Demethylepipodophyllotoxi 4’-Dmethylepipodophyllotoxin 4'-Demethylepipodophyllotoxin USP/EP/BP Etoposide EP Impurity E (4'-Demethyl epi-Podophyllotoxin (DMEP)) (5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one Teniposide Related Compound A (4''-Demethylepipodophyllotoxin) (1643747) Teniposide USP Related Compound A Podophyllotoxin EP Impurity B 4'-Demethylepipodophyllotoxin 4'-Demethyl epi-Podophyllotoxin (DMEP) Podophyllotoxin EP Impurity B (4'-Demethyl Epi-Podophyllotoxin (Dmep)) 4''-Demethylepipodophyllotoxin 4''-Demethylepipodophyllotoxin, 10 mM in DMSO 6559-91-7 559-91-7 C21H20O8 phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors Miscellaneous Natural Products Plant Oils, Toxins, Phenolic Acids & Derivatives chemical reagent pharmaceutical intermediate SiChem