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ChemicalBook >> CAS DataBase List >>S(-)-BAY K 8644

S(-)-BAY K 8644

S(-)-BAY K 8644 Structure
S(-)-BAY K 8644 structure
CAS No.
98625-26-4
Chemical Name:
S(-)-BAY K 8644
Synonyms
R-5417;BAY-r-5417;S(-)-BAY K 8644;Bay-K-8644 ((S)-(-)-);S(-)-BAY K 8644 CA2+ CHANNEL ACTIVATO;Bay-K-8644 (S)-(-)-[(S)-(-)-Bay-K-8644;Ca channels,Inhibitor,(S) ( ) Bay K 8644,inhibit,(S)()BayK8644,Calcium Channel,Ca2+ channels;methyl (-)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]pyridine-3-carboxylate;Methyl (S)-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate;(4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethyl)phenyl)-3-pyridinecarboxylicacidmethylester
CBNumber:
CB6448884
Molecular Formula:
C16H15F3N2O4
Molecular Weight:
356.3
MDL Number:
MFCD00153769
MOL File:
98625-26-4.mol
Last updated:2023-09-04 15:51:00
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S(-)-BAY K 8644 Properties

storage temp. 2-8°C
solubility H2O: slightly soluble
form solid
color yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26-36
WGK Germany  3
HS Code  2933399990
NFPA 704
0
2 0

S(-)-BAY K 8644 price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B133 (S)-(?)-Bay K8644 ≥98% (HPLC), solid 98625-26-4 1mg $229 2024-03-01 Buy
Sigma-Aldrich B133 (S)-(?)-Bay K8644 ≥98% (HPLC), solid 98625-26-4 5mg $905 2024-03-01 Buy
Cayman Chemical 19988 (S)-(?)-Bay K8644 ≥98% 98625-26-4 500μg $32 2024-03-01 Buy
Cayman Chemical 19988 (S)-(?)-Bay K8644 ≥98% 98625-26-4 1mg $61 2024-03-01 Buy
Cayman Chemical 19988 (S)-(?)-Bay K8644 ≥98% 98625-26-4 5mg $214 2024-03-01 Buy
Product number Packaging Price Buy
B133 1mg $229 Buy
B133 5mg $905 Buy
19988 500μg $32 Buy
19988 1mg $61 Buy
19988 5mg $214 Buy

S(-)-BAY K 8644 Chemical Properties,Uses,Production

Uses

(S)-(-)-Bay K8644 has been used as a L-type calcium channel (LTCC) agonist in the suprachiasmatic nucleus (SCN) slices. It has also been used as a LTCC agonist to induce arrhythmia?in rats.

Definition

ChEBI: (S)-Bay-K-8644 is a methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate in which the 4-position has (S)-configuration. It is an enantiomer of a (R)-Bay-K-8644.

General Description

(S)-(-)-Bay K8644, a dihydropyridine compound is a Ca2+?channel activator. It is an enantiomer of Bay K 8644.

Biological Activity

L-type Ca 2+ -channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo . Enantiomer of (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ).

Biochem/physiol Actions

(S)-(-)-Bay K8644 enhances Ca2+ current, whereas the (+)-Bay K 8644 is a weak Ca2+ channel antagonist. Bay K 8644 is lipophilic and it effectively scavenges superoxide anions.

storage

Store at +4°C

S(-)-BAY K 8644 Preparation Products And Raw materials

Raw materials

Preparation Products

S(-)-BAY K 8644 Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189 mychess007@163.com China 1994 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
InvivoChem 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
MedChemexpress LLC 58
ShangHai KenEn Chemical Technology Co., Ltd. 55
Sigma-Aldrich 80
EMMX Biotechnology LLC 60

S(-)-BAY K 8644 Spectrum

S(-)-BAY K 8644(98625-26-4)1HNMR

98625-26-4(S(-)-BAY K 8644)Related Search:

3-[o-(alpha,alpha,alpha-trifluorotolyl)]propionic acid 2-methyl-1-nitropropane Phenibut BAY K-8644 (+/-),(+/-)-BAY K 8644,(RS)-BAY K 8644,(+/-)-BAY K8644 CALCIUM SLOW CHANNEL 3-[(2-TRIFLUOROMETHYL)PHENYL]-1-PROPENE
3-(2-TRIFLUOROMETHYL-PHENYL)-PROPAN-1-OL 1-NITRO-2-METHYL-BUTANE o-(trifluoromethyl)phenethylamine METHYL (R)-3-PHENYLBUTYRATE S(-)-BAY K 8644
4-AMINO-3-PHENYL-1-BUTANOL 3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE METHYL 4-NITROBUTYRATE BETA-(NITROMETHYL)-BENZENEPROPANOIC ACID R(+)-BAY K 8644 CA2(+) CHANNEL BLOCKE,(+/-)-BAY K 8644, 0 TO 5 °C,R(+)-BAY K 8644 98% 0 C,R(+)-BAY K 8644
BAY K-8644 (+/-),(+/-)-BAY K 8644 (+/-) CAGED BAY K 8644 R(+)-BAY K 8644, CALCIUM CHANNEL

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S(-)-BAY K 8644 (4S)-1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[(2-TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER S(-)-BAY K 8644 CA2+ CHANNEL ACTIVATO (4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethyl)phenyl)-3-pyridinecarboxylicacidmethylester s-(-)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester [4S,(-)]-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethylphenyl)pyridine-3-carboxylic acid methyl ester BAY-r-5417 R-5417 Bay-K-8644 ((S)-(-)-) methyl (-)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]pyridine-3-carboxylate 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-, methyl ester, (4S)- Bay-K-8644 (S)-(-)-[(S)-(-)-Bay-K-8644 Ca channels,Inhibitor,(S) ( ) Bay K 8644,inhibit,(S)()BayK8644,Calcium Channel,Ca2+ channels Methyl (S)-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate 98625-26-4 C16H15F3N2O4 BioChemical Cell Signaling and Neuroscience Cell Biology Calcium Channel Modulators Inhibitors and Activators Ion Channels Voltage-gated Ion Channels Calcium channel