ChemicalBook >> CAS DataBase List >>4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

CAS No.
99010-64-7
Chemical Name:
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
Synonyms
cas 99010-64-7;Imiquimod USP RC C;Imiquimod Impurity-C;DesaMino ChloroiMiquiMod;1H-Imidazo[4,5-c]quinoline,;IMiquiMod Related CoMpound C;Imiquimod USP Related Compound C;4-Chloro-1-isobutyl-1H-imidazo[4,5-;1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(;4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
CBNumber:
CB6449735
Molecular Formula:
C14H14ClN3
Molecular Weight:
259.73
MDL Number:
MFCD06658174
MOL File:
99010-64-7.mol
Last updated:2024-01-09 10:21:27

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Properties

Melting point 139-140 °C(Solv: isopropanol (67-63-0))
Boiling point 427.5±48.0 °C(Predicted)
Density 1.29±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
pka 3.15±0.30(Predicted)
color White to Off-White
CAS DataBase Reference 99010-64-7(CAS DataBase Reference)
FDA UNII NJ5E4GY4NY

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2934990002

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1338346 Imiquimod Related Compound C United States Pharmacopeia (USP) Reference Standard 99010-64-7 25MG $1230 2022-05-15 Buy
Usbiological 446210 Desamino Chloroimiquimod 99010-64-7 5mg $460 2021-12-16 Buy
TRC D288295 DesaminoChloroimiquimod 99010-64-7 5mg $185 2021-12-16 Buy
AK Scientific S437 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 99010-64-7 10g $49 2021-12-16 Buy
AK Scientific S437 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 99010-64-7 25g $100 2021-12-16 Buy
Product number Packaging Price Buy
1338346 25MG $1230 Buy
446210 5mg $460 Buy
D288295 5mg $185 Buy
S437 10g $49 Buy
S437 25g $100 Buy

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Chemical Properties,Uses,Production

Description

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is a chemical product that has been used as a photosynthetic activator in weed science and pest control. It has been shown to significantly increase the growth rate of wheat, soybean, and oilseed crops. It is also effective at controlling weeds by inhibiting their ability to produce chlorophyll, thereby preventing them from photosynthesizing. 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline has also been shown to be an effective herbicide for agricultural use.

Uses

Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.

Synthesis

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is prepared by the reaction of 2-chloro-N4-(2-methylpropyl)quinoline-3,4-diamine and orthoformic acid triethyl ester. The specific synthesis steps are as follows:
A suspension of 2-chloro-N4 -(2-methylpropyl)-3,4-quinolinediamine (35 g) and triethylorthoformate (52.3 g, 2.5 eq) was heated at 145° C. for 10 h, during which time ethanol was removed by distillation. The resulting mixture was cooled to room temperature and the solid was removed by filtration. The solid was dissolved in hydrochloric acid (100 mL, 4N). The resulting solution was added to a solution of sodium hydroxide. The precipitate was filtered and washed with water to afford the product 4-chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline in 92% yield.
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline synthesis

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 172)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9352 55
Shanxi Naipu Import and Export Co.,Ltd
+86-13734021967 +8613734021967 kaia@neputrading.com China 1011 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135 sales@nbinno.com CHINA 925 58
Shanghai Arbor Chemical Co., Ltd.
021-60451682 act@arborchemical.com CHINA 906 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 7838 58

View Lastest Price from 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-chloro-1-(2-methylpropyl)-1h-imidazo(4,5-c)quinoline pictures 2022-04-14 4-chloro-1-(2-methylpropyl)-1h-imidazo(4,5-c)quinoline
99010-64-7
US $80.00 / bag 1bag 99 500 Shanxi Naipu Import and Export Co.,Ltd
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline pictures 2019-07-06 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
99010-64-7
US $1.00 / KG 1KG 90%-99.99% 1000kgs Career Henan Chemical Co
4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE 4-CHLORO-1-ISOBUTYL-1H-IMIDAZOBEN[4,5-C]QUINOLINE 1-[2-METHYLPROPYL]-1H-2-CHLOROIMIDAZO-[4,5-C]QUINOLINE 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(2-METHYLPROPYL) 4-Chloro-1-(2-methylpropyl)-1H-imidazo-(4,5c)quinolinone 2-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINONE 1H-Imidazo[4,5-c]quinoline, 4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE 1H-Imidazo[4,5-c]quinoline, -chloro-1-(2-methylpropyl)- 1H-Imidazo[4,5-c]quinolinone,2-chloro-1-(2-methylpropyl) Imiquimod Related Compound C (25 mg) (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline) 1-H-IMIDAZO[4,5-C]QUINOLINONE,4-CHLORO-1-(2-METHYL PROPYL) IMiquiMod Related CoMpound C DesaMino ChloroiMiquiMod 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline###4-Chloro-1-(2-methylpropyl)-1H-imidazole[4,5-c]quinoline 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-( 4-chloro-1-(2-methylpropyl)imidazo[4,5-c]quinoline Imiquimod USP Related Compound C 4-Chloro-1-isobutyl-1H-imidazo[4,5- Imiquimod USP RC C Imiquimod Impurity 3 (Imiquimod Related Compound C) Imiquimod Impurity-C Imiquimod Related Compound C (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline) (1338346) 4-CHLORO-1-ISOBUTYL-1H-IMIDAZO (4,5'D)QUINOLINE cas 99010-64-7 99010-64-7 C14H14ClN3 Quinolines, Quinazolines and derivatives Intermediates of Imiquimod API intermediates