ChemicalBook >> CAS DataBase List >>GGTI-298
GGTI-298
- CAS No.
- 180977-44-0
- Chemical Name:
- GGTI-298
- Synonyms
- CS-2228;GGTI-298;GGTI298 (GGTI-298;GGTI-298 free base;GGTI298 (CF3CO2H)salt;GGTI-298 trifluoroacetate salt;N-4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-NAPHTHYLBENZOYL-(L)-LEUCINE METHYL ESTER, TFA;L-Leucine, N-[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester;N-[[4-(2-(R)-AMINO-3-MERCAPTOPROPYL)AMINO]-2-NAPHTHYLBENZOYL]LEUCINE METHYL ESTER TRIFLUOROACETATE SALT;N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-(1-naphthalenyl)benzoyl]-L-leucinemethylestertrifluoroacetatesalt
- CBNumber:
- CB6450528
- Molecular Formula:
- C27H33N3O3S
- Molecular Weight:
- 479.63
- MDL Number:
- MFCD06409252
- MOL File:
- Mol file
Last updated:2023-07-12 17:07:59
Melting point | 99.5-100 °C |
---|---|
Boiling point | 673.7±55.0 °C(Predicted) |
Density | 1.190±0.06 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | DMSO: 22 mg/mL |
form | solid |
pka | 9.83±0.10(Predicted) |
color | off-white |
FDA UNII | ELA97V8Q7P |
GGTI-298 price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Tocris | 2430 | GGTI298 ≥95%(HPLC) | 180977-44-0 | 1 | $212 | 2021-12-16 | Buy |
Usbiological | 255374 | GGTI 298 | 180977-44-0 | 1mg | $460 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611699 | GGTI298 | 180977-44-0 | 5mg | $555.9 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0001112 | GGTI-298 95.00% | 180977-44-0 | 0.25MG | $599.45 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611699 | GGTI298 | 180977-44-0 | 1mg | $306 | 2021-12-16 | Buy |
GGTI-298 Chemical Properties,Uses,Production
Uses
GGTI 298 is a CAAX peptidomimetic that selectively inhibits geranylgeranyltransferase I (GGTase I). It has been shown to arrest human tumor cells and induce apoptosis.
Definition
ChEBI: (2S)-2-[[[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)phenyl]-oxomethyl]amino]-4-methylpentanoic acid methyl ester is a leucine derivative.
GGTI-298 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 71)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30256 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50001 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
ATK CHEMICAL COMPANY LIMITED | 60 |
BOC Sciences | 58 |
TargetMol Chemicals Inc. | 58 |
Career Henan Chemica Co | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 58 |
InvivoChem | 58 |
GIHI CHEMICALS CO.,LIMITED | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
VDM Biochemicals | 64 |
Sigma-Aldrich | 80 |
GGTI-298
N-[[4-(2-(R)-AMINO-3-MERCAPTOPROPYL)AMINO]-2-NAPHTHYLBENZOYL]LEUCINE METHYL ESTER TRIFLUOROACETATE SALT
N-4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-NAPHTHYLBENZOYL-(L)-LEUCINE METHYL ESTER, TFA
GGTI-298 trifluoroacetate salt
N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt
N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-(1-naphthalenyl)benzoyl]-L-leucinemethylestertrifluoroacetatesalt
GGTI298 (CF3CO2H)salt
CS-2228
GGTI298
(GGTI-298
methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate,2,2,2-trifluoroacetic acid
L-Leucine, N-[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester
GGTI-298 free base
180977-44-0
C27H33N3O3SC2HF3O2
C27H33N3O3SCF3CO2H
A cell-permeable, prodrug form of the GGTase I inhibitor GGTI-297.