ChemicalBook >> CAS DataBase List >>D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL

CAS No.
716-61-0
Chemical Name:
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
Synonyms
(1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL;ChloromycinbaseL-base;levoamine;Chloromycin base;L-BASE (AMINODIOL);chloramphenicolbase;D(-)Threo-1-(4-nitro;Chloramphenicol impurity D;Chloramphenicol Impurity 1;Aminonitrophenolpropanediol
CBNumber:
CB6452870
Molecular Formula:
C9H12N2O4
Molecular Weight:
212.2
MDL Number:
MFCD00078126
MOL File:
716-61-0.mol
MSDS File:
SDS
Last updated:2023-09-27 18:11:14

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Properties

Melting point 163-165 °C(lit.)
Boiling point 352.03°C (rough estimate)
Density 1.3136 (rough estimate)
refractive index -30.5 ° (C=1, 6mol/L HCl)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
Water Solubility almost transparency in hot Water
solubility DMSO (Slightly), Methanol (Slightly)
pka 10.98±0.45(Predicted)
form Powder
color Light yellow
optical activity [α]25/D 30°, c = 1 in 6 M HCl
InChIKey OCYJXSUPZMNXEN-RKDXNWHRSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn,T
Risk Statements  22-36/37/38-45
Safety Statements  26-45-53-22
RIDADR  UN 3259 8/PG 3
WGK Germany  3
RTECS  TY3100000
HS Code  29221990
NFPA 704
0
2 0

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A70704 (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 99% 716-61-0 10g $107 2024-03-01 Buy
Sigma-Aldrich A70704 (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 99% 716-61-0 25g $146 2024-03-01 Buy
TCI Chemical A1017 D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol >98.0%(T) 716-61-0 25g $79 2024-03-01 Buy
TCI Chemical A1017 D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol >98.0%(T) 716-61-0 500g $689 2024-03-01 Buy
TRC A622680 D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 716-61-0 50g $240 2021-12-16 Buy
Product number Packaging Price Buy
A70704 10g $107 Buy
A70704 25g $146 Buy
A1017 25g $79 Buy
A1017 500g $689 Buy
A622680 50g $240 Buy

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Chemical Properties,Uses,Production

Chemical Properties

light yellow powder

Uses

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol may be used in the preparation of (1R,2R)-(-)-2-dimethylamino-1-(4-nitrophenyl)-1,3-propanediol via N,N-dimethylation. It may also be used as a starting material to synthesize (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propylisothioeyanate [(R,R)-DANI].

Uses

D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chloramphenicol (C325030), a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuel ae.

Uses

Chloramphenicol base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol and is a degradation product commonly encountered with commercial production of chloramphenicol. Chloramphenicol base has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol.

Definition

ChEBI: A diol that is propane 1,3-diol bearing additional amino and 4-nitrophenyl substituents at positions 2 and 1 respectively.

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 221)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5993 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58

View Lastest Price from D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ChloromycinbaseL-base pictures 2023-09-27 ChloromycinbaseL-base
716-61-0
US $10.00-3.00 / kg 1kg 0.99 15 tons Hebei Yanxi Chemical Co., Ltd.
ChloromycinbaseL-base pictures 2023-09-06 ChloromycinbaseL-base
716-61-0
US $0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
D(-)Threo-1-(4-nitrophenyl)-2-amino-1,3-propanediol pictures 2023-05-04 D(-)Threo-1-(4-nitrophenyl)-2-amino-1,3-propanediol
716-61-0
US $48.00-40.00 / KG 1KG 99% 200tons Guangzhou Sunton Biotechnology Co., Ltd.
(1R,2R)-1-(4-Nitrophenyl)-2-aminopropane-1,3-diol [1R,2R,(-)]-2-Amino-1-(p-nitrophenyl)-1,3-propanediol (1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol,96% (1R,2R)-()-2-Amino-1-(4-nitrophenyl)-1,3-propanediol,D-()-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base (1R,2R)-2-AMino-1-(4-nitrophenyl)propane-1,3-diol, 96% 5GR (1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol 99% (1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol, 96%, 96% (1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol hydrochloride L-BASE (AMINODIOL) D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol (1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol≥ 99% (by Assay) d-threo-(-)-2-amino-1-(p-nitrophenyl)-1,3-propanediol levoamine Chloromycin base 2-amino-1-(p-nitrophenyl)-3-propanediod-threo-(-)- chloramphenicolbase Chloramphenicol base, D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL D(-)THREO-1-(4-NITRO-PHENYL)-2-AMINO-1,3-PROPANEDIOL CHLORAMPHENICOL-WATER SOLUBLE (1R,2R)-2-AMINO-1-(4-NITROPHENOL)PROPANE-1,3-DIOL (1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL CHLORAMPHENICOL BASE CRYSTALLINE (1R,2R)-(-)-2-AMINO-1-ITROPHENYL)-1,3-PR OPANEDIOL,99% D(-)Threo-1-(4-nitro-phenyl)-2 1,3-Propanediol, 2-amino-1-(4-nitrophenyl)-, (1R,2R)- D-THREO-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANE (1R,2R)-(-)-2-AMINO-1-NITROPHENYL)-1,3-PROPANEDIOL D-(-)threo-2-amino-1-(p-nitrophenyl)propane-1,3-diol (R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol D-(-)-THREO-2-AMINO-1-(4-NITRO (1R,2R)-(-)-2-Amino-1-(4-nitrophenyL (1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol nitrate Chloramphenicol impurity D (D)-(-)-threo-2-Amino-1-(4-nitrophe Chloramphenicol Impurity 1 (D-(-)-Threo-2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol) D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol > Chloramphenicol Impurity 1 D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL USP/EP/BP D(-)Threo-1-(4-nitro (1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-aminium (1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL ChloromycinbaseL-base D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol/D-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Aminonitrophenolpropanediol D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol, ≥ 98.0% 716-61-0 C9H12O4N2 HOCH2CHNH2CHC6H4NO2OH C9H13N2O4 AMINE Amino Alcohols Asymmetric Synthesis Organic Building Blocks Optical Resolution Chiral Building Blocks for Resolution of Acids Amino Alcohols (Chiral)