Tilmicosin | 108050-54-0

Tilmicosin Properties

Melting point	>97°C (dec.)
alpha	D23 +12.75° (c = 0.010004 in CHCl3, 5 cm)
Boiling point	926.6±65.0 °C(Predicted)
Density	1.18±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Acetone (Slightly), DMSO (Slightly), Methanol (Sparingly)
pka	pKa (66% DMF): 7.4, 8.5(at 25℃)
color	White to Off-White
InChIKey	JTSDBFGMPLKDCD-XVFHVFLVSA-N
FDA 21 CFR	556.735; 558.618; 558.4
FDA UNII	XL4103X2E3
EPA Substance Registry System	Tilmicosin (108050-54-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
WGK Germany	3
HS Code	29419090

Tilmicosin price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	33864	Tilmicosin VETRANAL?, analytical standard, mix of isomers	108050-54-0	100mg	$119	2024-03-01	Buy
Sigma-Aldrich	1667370	Tilmicosin United States Pharmacopeia (USP) Reference Standard	108050-54-0	250mg	$436	2024-03-01	Buy
Usbiological	257406	Tilmicosin	108050-54-0	500mg	$531	2021-12-16	Buy
TRC	T440500	Tilmicosin,85%	108050-54-0	50mg	$70	2021-12-16	Buy
AK Scientific	A574	Tilmicosin,mixtureofisomers	108050-54-0	1g	$312	2021-12-16	Buy

Product number	Packaging	Price	Buy
33864	100mg	$119	Buy
1667370	250mg	$436	Buy
257406	500mg	$531	Buy
T440500	50mg	$70	Buy
A574	1g	$312	Buy

Tilmicosin Chemical Properties,Uses,Production

Brief introduction

Tilmicosin is a relatively novel semi-synthetic macrolide antibiotics derived from tylosin for being applied to livestock and poultry. The chemical name is 4A-O-de (2, 6-dideoxy-methyl-3-C--L-ribose-pyran-hexyl)-20-deoxy-20-(3,5-dimethyl-1-piperidinyl)-[20 (cis: trans)] tylosin. Molecule formula is C46H80N2O13 and the molecular weight of 869.15.
Tilmicosin has a similar antibacterial spectrum as tylosin but has enhanced effect on the anti-Pasteurella multocida and hemolytic pasteurella. It was successfully developed in 1980s and initially used with a code of EL-870. Common trade names include Pulmotil © Micotil ©, preparations include tilmicosin soluble powder, premix (20%) preparation, and injection. In 1990 it was approved in most European countries; it was approved in the US in 1992, and included in USP. China also has some domestic enterprises approved for production of tilmicosin.
Because of its special antibacterial activity and pharmacokinetic characteristics, the drug has been approved for clinical prevention and treatment of infectious diseases for cattle, goats, sheep, cows, pigs, and chickens. It is especially applied to the treatment of respiratory diseases of livestock, such as cattle Actinobacillus pleuropneumonia, Pasteurella disease, chicken mycoplasmosis and mastitis of lactating animals.
The above information is edited by the Chemicalbook of Dai Xiongfeng.

Chemical Properties

It is white or white powder with humidity: ≤5.0%.

Uses

It can be used as anti-bacterial.
It is mainly used for the treatment of infection caused by pleuropneumonia, Actinobacillus, Pasteurella and mycoplasma.

Chemical Properties

White Solid

Uses

Tilmicosin is a semi-synthetic antibiotic derived from desmycosin (tylosin B), a minor co-metabolite of tylosin. Tilmicosin is produced by reductive amination of desmycosin. Desmycosin itself is prepared by the partial hydrolysis of tylosin with the loss of the mycarosyl sugar. The piperidinyl group at C20 of tilmicosin provides a wider spectrum of antibiotic action, in particular good protection against Pasteurella in livestock.

Uses

A Macrolide antibiotic.

Uses

Macrolide antibiotic structurally related to tylosin. Antibacterial

Veterinary Drugs and Treatments

Tilmicosin is indicated for the treatment of bovine or ovine respiratory diseases (BRD) caused by Mannheimia (Pasturella) haemolytica.

Tilmicosin Preparation Products And Raw materials

Raw materials

Preparation Products

Tilmicosin Suppliers

Global( 418)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
shandong perfect biotechnology co.ltd	+86-53169958659; +8618596095638	sales@sdperfect.com	China	294	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	sarah@tnjone.com	China	893	58
Henan Suikang Pharmaceutical Co.,Ltd.	+8618239973690	sales@suikangpharm.com	China	178	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hubei XinRunde Chemical Co., Ltd.	+8615102730682	bruce@xrdchem.cn	CHINA	566	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
shandong perfect biotechnology co.ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Nantong Guangyuan Chemicl Co,Ltd	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Henan Suikang Pharmaceutical Co.,Ltd.	58
Henan Tianfu Chemical Co.,Ltd.	55
Hubei XinRunde Chemical Co., Ltd.	55
career henan chemical co	58

View Lastest Price from Tilmicosin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-26	Tilmicosin 108050-54-0	US $0.00 / kg	25kg	＞85%	10tons	Henan Suikang Pharmaceutical Co.,Ltd.
2024-04-16	Tilmicosin 108050-54-0	US $0.00-0.00 / kg	1kg	85%	1000kg	Hebei ZB Gamay Biological Technology Co.,Ltd
2024-03-27	Tilmicosin 108050-54-0	US $0.00 / KG	1KG	99%	2000KG	Shaanxi TNJONE Pharmaceutical Co., Ltd

Tilmicosin
108050-54-0
US $0.00 / kg
＞85%
Henan Suikang Pharmaceutical Co.,Ltd.

Tilmicosin
108050-54-0
US $0.00-0.00 / kg
85%
Hebei ZB Gamay Biological Technology Co.,Ltd

Tilmicosin
108050-54-0
US $0.00 / KG
99%
Shaanxi TNJONE Pharmaceutical Co., Ltd

Tilmicosin Spectrum

Tilmicosin(108050-54-0)MS

108050-54-0(Tilmicosin)Related Search:

TILMICOSIN PHOSPHATE Dacthal Dimethyl ether Dimethyl carbonate ETHANE

N,N-Dimethylformamide Dimethyl disulfide Dimethyl fumarate Dimethyl sulfoxide Dimethyl sulfate

Dimethyl phthalate Tilorone dihydrochloride Tilmicosin phosphate 8,10-DODECADIEN-1-OL Tilmicosin (FDA)

Tylosin ISO-PROPYL-UNDECYLENATE (R)-3-METHYL-4-TETRAHYDROPYRANYLOXYBUTYLAMINE

1of4

4'-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)tyrosine [antibiotic] Tilmicosin,20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin Tilmicosin (250 mg) Herba Dianthi Superbi (11Z,13Z)-6-{[4-(diMethylaMino)-3,5-dihydroxy-6-Methyloxan-2-yl]oxy}-7-[2-(3,5-diMethylpiperidin-1-yl)ethyl]-16-ethyl-4-hydroxy-15-{[(5-hydroxy-3,4-diMethoxy-6-Methyloxan-2-yl)oxy]Methyl}-5,9,13-triMethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione 20-Deoxy-20-(3,5-diMethylpiperidin-1-yl)-desMycosin, EL-870 Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]- 20%Tilmicosin Tilmicosin Base 20-DEOXO-20-(3,5-DIMETHYL-1-PIPERIDINYL)DESMYCOSIN Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-.alpha.-L-ribo-hexopyranosyl)-20-deoxo-20-(3R,5S)-3,5-dimethyl-1-piperidinyl- TILMICOSIN Tilmicosin, Vetranal 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin Antibiotic EL 870 EL 870 LY 177370 Micotil Micotil 300 4A-O-De(2,6-dideoxy-3-C-methyl-a-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin Stmicco Tilmicosin Solution, 1000ppm Tilmicosin CAS 108050-54-0 Tilmicosin,85% Qumai extract 6-[[4-(dimethylamino)-3,5-dihydroxy-6-methyl-2-oxanyl]oxy]-7-[2-(3,5-dimethyl-1-piperidinyl)ethyl]-16-ethyl-4-hydroxy-15-[(5-hydroxy-3,4-dimethoxy-6-methyl-2-oxanyl)oxymethyl]-5,9,13-trimethyl-1-oxacy Tilmicosin Standard(mixture of isomers) (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-4-(Dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-(2-((3R,5S)-3,5-dimethylpiperidin-1-yl)ethyl)-16-ethyl-4-hydroxy-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-5,9,13-trimethyloxacyclohexadeca-11,13-diene-2,10-dione Tilmicosin USP/EP/BP Dianthi extract TilmicosinQ: What is Tilmicosin Q: What is the CAS Number of Tilmicosin Q: What is the storage condition of Tilmicosin Q: What are the applications of Tilmicosin Tilmicosin (API) Tilmicosin (1667370) pulmotil Tilmicosine Dianthi Herba Timicosin Timicoxin 108050-54-0 08050-54-0 C46H80N2O13 API Pharmaceutical intermediate Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents Active Pharmaceutical Ingredients