ChemicalBook >> CAS DataBase List >>4-Acetylbenzonitrile

4-Acetylbenzonitrile

4-Acetylbenzonitrile structure

CAS No.: 1443-80-7

Chemical Name:: 4-Acetylbenzonitrile

Synonyms: 4-CYANOACETOPHENONE;p-Cyanacetophenon;4-AcetyL;AKOS 90467;P-CYANOACETOPHENONE;4-Cyano acetopheone;P-ACETYLBENZONITRILE;4-ACETYLBENZONITRILE;4'-caynoacetophenone;4'-Cyanoacetophenone

CBNumber:: CB6464660

Molecular Formula:: C9H7NO

Molecular Weight:: 145.16

MDL Number:: MFCD00001825

MOL File:: 1443-80-7.mol

MSDS File:: SDS

Last updated:2026-01-13 11:20:46

Product description	Number	Pack Size	Price
4-Acetylbenzonitrile 99%	154393	5g	$150
4-Acetylbenzonitrile 99%	154393	25g	$658
4'-Cyanoacetophenone >97.0%(GC)	C1141	10g	$30
4'-Cyanoacetophenone >97.0%(GC)	C1141	25g	$51
p-Cyanoacetophenone	C987505	1g	$85
More product size

Request For Quotation

4-Acetylbenzonitrile Properties

Melting point	56-59 °C(lit.)
Boiling point	95-96°C 14mm
Density	1.1555 (rough estimate)
vapor pressure	0.856Pa at 25℃
refractive index	1.4500 (estimate)
Flash point	95-96°C/14mm
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform
form	Crystalline Mass or Crystalline Powder and Chunks
color	Light yellow to yellow-beige
Water Solubility	Soluble in chloroform. Insoluble in water.
BRN	1932887
InChI	InChI=1S/C9H7NO/c1-7(11)9-4-2-8(6-10)3-5-9/h2-5H,1H3
InChIKey	NLPHXWGWBKZSJC-UHFFFAOYSA-N
SMILES	C(#N)C1=CC=C(C(C)=O)C=C1
LogP	1.531 at 25℃
CAS DataBase Reference	1443-80-7(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312

Precautionary statements

P264-P270-P280-P301+P312-P302+P352+P312-P362+P364

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xn,Xi

Risk Statements

22-36/37/38-20/21/22

Safety Statements

36-36/37/39-26-22

RIDADR

3276

WGK Germany

Hazard Note

Harmful/Irritant

HazardClass

6.1

PackingGroup

III

HS Code

29269090

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Oral

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
2		0

4-Acetylbenzonitrile price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	154393	4-Acetylbenzonitrile 99%	1443-80-7	5g	$150	2026-04-30	Buy
Sigma-Aldrich	154393	4-Acetylbenzonitrile 99%	1443-80-7	25g	$658	2026-04-30	Buy
TCI Chemical	C1141	4'-Cyanoacetophenone >97.0%(GC)	1443-80-7	10g	$30	2026-04-30	Buy
TCI Chemical	C1141	4'-Cyanoacetophenone >97.0%(GC)	1443-80-7	25g	$51	2026-04-30	Buy
TRC	C987505	p-Cyanoacetophenone	1443-80-7	1g	$85	2021-12-16	Buy

Product number	Packaging	Price	Buy
154393	5g	$150	Buy
154393	25g	$658	Buy
C1141	10g	$30	Buy
C1141	25g	$51	Buy
C987505	1g	$85	Buy

4-Acetylbenzonitrile Chemical Properties,Uses,Production

Chemical Properties

light yellow to yellow-beige crystalline mass or crystalline powder and chunks

Uses

4-Acetylbenzonitrile is used in the preparation of antimalarial isonitriles. It is also used for synthetic API such as anesthetic agents and anti-allergic agents.

Uses

4-Acetylbenzonitrile can be used in the preparation of antimalarial isonitriles.

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 1613, 1979 DOI: 10.1021/jo01324a006
Tetrahedron Letters, 28, p. 1345, 1987 DOI: 10.1016/S0040-4039(00)95366-8

General Description

The relaxation-assisted two-dimensional infrared (RA 2DIR) spectroscopy of 4-acetylbenzonitrile was analyzed.

Flammability and Explosibility

Not classified

Purification Methods

Recrystallise the nitrile from EtOH [Wagner et al. J Am Chem Soc 108 7727 1986]. [Beilstein 10 H 695, 10 III 3030.]

4-Acetylbenzonitrile synthesis

Synthesis of 4-Acetylbenzonitrile from 4-Ethynylbenzonitrile

4-Acetylbenzonitrile Preparation Products And Raw materials

Raw materials

4-Ethylbenzonitrile

Preparation Products

4-(1,2,3-THIADIAZOL-4-YL)BENZOIC ACID 4-(1,2,3-THIADIAZOL-4-YL)BENZOYL CHLORIDE 4-(1,2,3-THIADIAZOL-4-YL)BENZONITRILE N-methylacridine 1-[4-(aminomethyl)phenyl]ethan-1-ol

Benzonitrile, 4-(1-aminoethyl)- (S)-1-(4-CYANOPHENYL)ETHANAMINE 3-(4-CYANO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Ravuconazole (4-ethylphenyl)methanamine hydrochloride

4-CYANOPHENYLGLYOXAL HYDRATE 4-Cyanophenylglyoxal hydrate

1of3

4-Acetylbenzonitrile Suppliers

Global( 399)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	997	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88298848	info@edengenechem.com	China	2176	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Hebei Chuanghai Biotechnology Co., Ltd	58
Shaanxi Haibo Biotechnology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Changzhou Ansciep Chemical Co., Ltd.	58
Jinan Carbotang Biotech Co.,Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Changzhou Ditong Chemical Co.,Ltd	58

View Lastest Price from 4-Acetylbenzonitrile manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	4-Acetylbenzonitrile 1443-80-7	US $10.00 / kg	1kg	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2024-04-12	4-Acetylbenzonitrile 1443-80-7	US $0.00 / kg	1kg	99%	2000ton	Shaanxi Haibo Biotechnology Co., Ltd
2021-12-22	4-Acetylbenzonitrile 1443-80-7	US $10.00 / KG	1KG	98%	500ton/Month	Qiuxian Baitai New Material Co., LTD

4-Acetylbenzonitrile
1443-80-7
US $10.00 / kg
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Acetylbenzonitrile
1443-80-7
US $0.00 / kg
99%
Shaanxi Haibo Biotechnology Co., Ltd

4-Acetylbenzonitrile
1443-80-7
US $10.00 / KG
98%
Qiuxian Baitai New Material Co., LTD

4-Acetylbenzonitrile Spectrum

4-Acetylbenzonitrile(1443-80-7)MS 4-Acetylbenzonitrile(1443-80-7)¹HNMR 4-Acetylbenzonitrile(1443-80-7)¹³CNMR 4-Acetylbenzonitrile(1443-80-7)IR1 4-Acetylbenzonitrile(1443-80-7)IR2 4-Acetylbenzonitrile(1443-80-7)Raman

1443-80-7(4-Acetylbenzonitrile)Related Search:

4-(2-Bromoacetyl)benzonitrile Naroparcil 1,4-DIAMINO-2,3-DICYANO-9,10-ANTHRAQUINONE 4-Acetylbenzonitrile 4-CYANOBENZOPHENONE

M-ACETYLBENZONITRILE,3-Acetylbenzonitrile97%,3-acetylbenzonitrile,98%,3-ACETYLBENZONITRILE 4-ACETYLBENZONITRILE,P-ACETYLBENZONITRILE 2-ACETYLBENZONITRILE Benzonitrile 4-CYANO-4'-METHOXYBENZOPHENONE

4-[[6-METHOXY-2-(4-METHOXYPHENYL)-3-BENZOFURANYL]CARBONYL]BENZONITRILE 9-OXO-9H-THIOXANTHENE-3-CARBONITRILE-10,10-DIOXIDE 6-(4-CYANOPHENYL)-6-OXOHEXANENITRILE 4-CYANO-3'-METHOXYBENZOPHENONE 4'-CYANO-2,2,2-TRIFLUOROACETOPHENONE

6-CYANO-1-TETRALONE 4-CYANO-2'-METHOXYBENZOPHENONE 5-(4-CYANOPHENYL)-5-OXOVALERONITRILE

1of4

Benzonitrile,p-acetyl- Methylp-cyanophenylketone Paracyanoacetophenone 4-ACETYLBENZONITRILE AKOS 90467 P-ACETYLBENZONITRILE P-CYANOACETOPHENONE 4-ACETYLBENZONITRILE / 4-CYANOACETOPHENONE 4'-Cyanoacetophenone 4-Acetylbenzonitrile p-Cyanoacetophenone 4-Acetylbenzonitrile99% 4-Acetylbenzonitrile, 98+% 4-Acetylbenzonitrile, 98+% 5GR 1-Acetyl-4-benzonitrile p-Cyanophenyl Methyl Ketone 4'-Cyanoacetophenone, 4-Ethanoylbenzonitrile 4-Acetylbenzonitrile 99% 4-Acetylbenzonitrile, 97+% 4'-Cyanoacetophenonele 4-Cyanophenyl methyl ketone 4-Cyanophenylmethylketone Benzonitrile, p-acetyl- Benzonitrile,4-acetyl- 4-AcetyL 4'-caynoacetophenone 4'-Cyanoacetophenone > p-Cyanoacetophenone,99% p-Cyanacetophenon 4-CYANOACETOPHENONE 4-Cyano acetopheone Ixaconazole - Intermediate 11（p-cyanoacetophenone） 4-ACETYLBENZONITRILE (25GMS) 4'-Cyanoacetophenone Isavuconazole Impurity N15 4-Acetylbenzonitrile, 95% 1443-80-7 ARYL ISOCYANATE Building Blocks C8 to C9 Organic Building Blocks Nitrogen Compounds Cyanides/Nitriles Building Blocks for Liquid Crystals Benzonitriles (Building Blocks for Liquid Crystals) Building Blocks C8 to C9 Chemical Synthesis Cyanides/Nitriles Nitrogen Compounds Organic Building Blocks Benzonitriles (Building Blocks for Liquid Crystals) Building Blocks for Liquid Crystals Functional Materials Aromatic Nitriles