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1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE

CAS No.
61216-62-4
Chemical Name:
1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE
Synonyms
SAPE;1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE;2-Ammonioethyl ((R)-2-(((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl)oxy)-3-(stearoyloxy)propyl) phosphate;5Z,8Z,11Z,14Z-eicosatetraenoicacid,(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxooctadecyl)oxy]ethylester;5,8,11,14-Eicosatetraenoic acid, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxooctadecyl)oxy]ethyl ester, (5Z,8Z,11Z,14Z)-
CBNumber:
CB64666879
Molecular Formula:
C43H78NO8P
Molecular Weight:
768.07
MDL Number:
MFCD00674346
MOL File:
61216-62-4.mol
Last updated:2023-06-08 09:02:56

1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE Properties

Boiling point 776.1±70.0 °C(Predicted)
Density 1.013±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Ethanol:PBS (pH 7.2)(1:2): 1 mg/ml; Methanol: 10 mg/ml
pka 1.17±0.50(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H302-H315-H319-H331-H336-H351-H361d-H372-H412
Precautionary statements  P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
NFPA 704
3
0 0

1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25871 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE ≥95% 61216-62-4 5mg $113 2024-03-01 Buy
Cayman Chemical 25871 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE ≥95% 61216-62-4 10mg $200 2024-03-01 Buy
Cayman Chemical 25871 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE ≥95% 61216-62-4 25mg $438 2024-03-01 Buy
Product number Packaging Price Buy
25871 5mg $113 Buy
25871 10mg $200 Buy
25871 25mg $438 Buy

1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE Chemical Properties,Uses,Production

Description

1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE is a naturally-occurring phospholipid that is formed via the phosphatidylserine decarboxylation pathway in mammalian cells. It has been used in the generation of giant unilamellar vesicles for use in the study of biological membranes.

Uses

SAPE is used in the mRNA combination therapy for treatment of cancer.

Uses

18:0-20:4 PE maybe used in the preparation of liposomes.

Definition

ChEBI: 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion is a phosphatidylethanolamine 38:4 zwitterion obtained by transfer of a proton from the phosphate to the primary amino group of 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-icosatetraenoyl)-sn-glycero-3-phosphoethanolamine; major species at pH 7.3. It is a phosphatidylethanolamine 38:4 zwitterion and a 1-stearoyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion. It is a tautomer of a 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine.

1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE Preparation Products And Raw materials

Raw materials

Preparation Products

1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
Creative Enzymes
1-516-855-7709 info@creative-enzymes.com United States 8748 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3444 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Jinan Sanbao Biotechnology Co., Ltd. 13854185395; 13854185395 sanbaobiotech@126.com China 8269 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Sichuan Yiyan Pharmaceutical Research 19949968070 2904199885@qq.com China 915 58
1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PE 5,8,11,14-Eicosatetraenoic acid, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxooctadecyl)oxy]ethyl ester, (5Z,8Z,11Z,14Z)- SAPE 5Z,8Z,11Z,14Z-eicosatetraenoicacid,(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxooctadecyl)oxy]ethylester 2-Ammonioethyl ((R)-2-(((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl)oxy)-3-(stearoyloxy)propyl) phosphate 61216-62-4