ChemicalBook >> CAS DataBase List >>BAY-885
BAY-885
- CAS No.
- 2307249-33-6
- Chemical Name:
- BAY-885
- Synonyms
- BAY-885;BAY-885 USP/EP/BP;BAY 885,ERK,inhibit,Extracellular signal regulated kinases,Inhibitor,BAY885,BAY-885;[2-amino-4-(trifluoromethoxy)phenyl]-{4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl}methanone;Methanone, [2-amino-4-(trifluoromethoxy)phenyl][4-[7-(4-methyl-1-piperazinyl)pyrido[3,2-d]pyrimidin-4-yl]-1-piperidinyl]-
- CBNumber:
- CB64667614
- Molecular Formula:
- C25H28F3N7O2
- Molecular Weight:
- 515.53
- MDL Number:
- MFCD32067879
- MOL File:
- 2307249-33-6.mol
Last updated:2023-09-20 16:43:00
| Boiling point | 685.0±55.0 °C(Predicted) |
|---|---|
| Density | 1.362±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility |
DMSO:23.33(Max Conc. mg/mL);45.25(Max Conc. mM) Ethanol:8.0(Max Conc. mg/mL);15.52(Max Conc. mM) |
| form | A solid |
| pka | 7.06±0.42(Predicted) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
BAY-885 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb611265 | BAY-885 >98% | 2307249-33-6 | 10mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611265 | BAY-885 >98% | 2307249-33-6 | 25mg | $1802 | 2021-12-16 | Buy |
| ChemScene | CS-0043294 | BAY885 99.15% | 2307249-33-6 | 50mg | $2600 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611265 | BAY-885 >98% | 2307249-33-6 | 50mg | $2691.1 | 2021-12-16 | Buy |
| ChemScene | CS-0043294 | BAY885 99.15% | 2307249-33-6 | 100mg | $3600 | 2021-12-16 | Buy |
BAY-885 Chemical Properties,Uses,Production
Use
BAY-885 is a highly potent and selective ERK5 inhibitor.
In vitro
BAY-885 shows potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and has no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM), thereby ruling out potential effects as a general inhibitor of transcription or translation.
BAY-885 Preparation Products And Raw materials
Raw materials
Preparation Products
BAY-885 Suppliers
Global( 33)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29067 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4121 | 55 | |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
BAY-885
[2-amino-4-(trifluoromethoxy)phenyl]-{4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl}methanone
Methanone, [2-amino-4-(trifluoromethoxy)phenyl][4-[7-(4-methyl-1-piperazinyl)pyrido[3,2-d]pyrimidin-4-yl]-1-piperidinyl]-
BAY-885 USP/EP/BP
BAY 885,ERK,inhibit,Extracellular signal regulated kinases,Inhibitor,BAY885,BAY-885
2307249-33-6
C25H28F3N7O2