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Pimobendan

Pimobendan
Pimobendan structure
CAS No.
74150-27-9
Chemical Name:
Pimobendan
Synonyms
Acardi;VetMedin;UD-CG 115;Pimobendam;PIMOBENDAN;UD-CG 115BS;Pimobendane;Pimobendanum;dl-Pimobendan;PiMobendan EP
CBNumber:
CB6472876
Molecular Formula:
C19H18N4O2
Formula Weight:
334.37
MOL File:
74150-27-9.mol

Pimobendan Properties

Melting point:
approximate 243℃ (dec.)
Density 
1.36
storage temp. 
2-8°C
solubility 
DMSO: soluble5mg/mL, clear (warmed)
form 
powder
pka
10.55±0.10(Predicted)
color 
white to beige
InChIKey
GLBJJMFZWDBELO-UHFFFAOYSA-N
CAS DataBase Reference
74150-27-9(CAS DataBase Reference)
FDA UNII
34AP3BBP9T
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310+P330
RIDADR  UN 2811 6.1 / PGIII
HS Code  2933995300

Pimobendan price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1333 Pimobendan for system suitability ≥98% (HPLC) 74150-27-9 10mg $98.6 2021-03-22 Buy
Sigma-Aldrich 1569315 Pimobendan for system suitability United States Pharmacopeia (USP) Reference Standard 74150-27-9 100mg $1120 2021-03-22 Buy
Cayman Chemical 26082 Pimobendan 74150-27-9 50mg $80 2021-03-22 Buy
Cayman Chemical 26082 Pimobendan 74150-27-9 100mg $151 2021-03-22 Buy
Sigma-Aldrich Y0000401 Pimobendan for system suitability European Pharmacopoeia (EP) Reference Standard 74150-27-9 y0000401 $190 2020-08-18 Buy

Pimobendan Chemical Properties,Uses,Production

Description

Pimobendan, a novel cardiotonic vasodilator, was introduced in Japan for the treatment of acute and mild to moderate chronic heart failure. It is a phosphodiesterase Ⅲ inhibitor and is able to enhance sensitization of myocardial contractile regulatory protein to calcium ions. The combination of these effects contribute to its inotropic activity. In patients with severe congestive heart failure, orally administered pimobendan improves cardiac index, stroke volume index, pulmonary wedge pressure, and systemic and pulmonary vascular resistance. Pimobendan is reported to be well tolerated and largely devoid of the proarrhythmic effects of classical phosphodiesterase Ill inhibitors. Studies also suggested that combination of the inotropic agent pimobendan with an ACE inhibitor such as enalapril may be superior to monotherapy for heart failure patients.

Chemical Properties

White Solid

Originator

Boehringer lngelhelm (Germany)

Uses

antiviral

Uses

Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.

Uses

Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM

brand name

Acardl

Veterinary Drugs and Treatments

Pimobendan is used to treat dogs with congestive heart failure secondary to dilated cardiomyopathy or chronic mitral valve insufficiency (CMVI).

Pimobendan Preparation Products And Raw materials

Raw materials

Preparation Products


Pimobendan Suppliers

Global( 224)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Ningbo Nuobai Pharmaceutical Co., Ltd.
0574-87684611
0574-87342797 Fisheryu@nbpharm.com China 14 58
Shaanxi Dideu Medichem Co. Ltd
15319487004
029-88380327 1015@dideu.com CHINA 4149 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
+86 (576) 8169-6105 sales@frappschem.com China 886 50
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
010-60279497 sales01@cooperate-pharm.com CHINA 1817 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29961 58
Tianjin Huiren Chemtech Co., Ltd
86-13672008665
86-22-23707858 huirentech@foxmail.com CHINA 110 58
GIHI CHEMICALS CO.,LIMITED
08657186217390
sales@gihichemicals.com CHINA 310 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58

View Lastest Price from Pimobendan manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-22 Pimobendan
74150-27-9
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2021-09-29 Pimobendan
74150-27-9
US $0.00 / Kg/Bag 1KG 98%-101%; EP/BP 100kgs WUHAN FORTUNA CHEMICAL CO., LTD
2021-09-14 Pimobendan
74150-27-9
US $3809.50 / KG 20g 99% 50kg Baoji Guokang Healthchem co.,ltd

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